Biochemistry News and Research

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New method detects potentially disease-causing forms of proteins using fluorescence

A new method uses fluorescence to detect potentially disease-causing forms of proteins as they unravel due to stress or mutations.

14 Feb 2019

Study discovers new therapy for aggressive blood cancer

Acute myeloid leukemia is the most common form of acute leukemia. It is characterized by an increase of malignant myeloid progenitor cells at the expense of mature blood cells.

13 Feb 2019

Cell membrane complexes may be new target for drugs to kill cancer cells

Old molecules and new complexes: researchers at Hollings Cancer Center at the Medical University of South Carolina have discovered cell membrane complexes called ceramidosomes that may be a new target for drugs to kill cancer cells.

13 Feb 2019

Marine snail venom reveals clues to developing faster-acting insulin for diabetic patients

Although moderately mobile, marine cone snails have perfected several strategies to capture prey. Some fish-hunting species release venom into the surrounding water.

12 Feb 2019

Newly discovered genetic disorder opens way for future diabetes drugs

Knowledge of a newly discovered genetic disorder, which means that a person cannot produce the protein TXNIP (thioredoxin interacting protein) in their cells, can open for the development of new diabetes drugs.

12 Feb 2019

Frequency of heteroresistance has been greatly underestimated, study finds

When antibiotics are used to treat bacteria susceptible to them, the treatment usually works. Nevertheless, the antibiotic chosen is sometimes ineffective. One of the reasons for this is heteroresistance, a phenomenon explored in depth by Uppsala and Emory University researchers in a new study.

12 Feb 2019

Research sheds light on how motor enzyme can promote genome integrity

Approximately one per cent of each organism's genome encodes helicases. Helicases are mostly known as motor enzymes that can unwrap double-stranded DNA by use of energy.

11 Feb 2019

Researchers identify genes that make Staphyloccocus bacteria resistant to treatment

A Rutgers-led team has discovered two genes that make some strains of harmful Staphyloccocus bacteria resistant to treatment by copper, a potent and frequently used antibacterial agent.

11 Feb 2019

When genomic sequencing fails to diagnose a rare disease

Routine sequencing has given unprecedented insight into the genetics of rare diseases, but genomics fails to diagnose up to half of patients who are tested. That's the problem German scientists tackled in a recent study in the journal Molecular & Cellular Proteomics.

11 Feb 2019

Metabolic plasticity helps metastatic cancer cells survive hostile environments

When metastatic cancer cells need to avoid a threat, they simply reprogram themselves. Rice University scientists are beginning to get a handle on how they survive hostile environments.

8 Feb 2019

Mutations in folliculin gene affect embryo implantation

New information is unfolding on the genetic controls of an early turning point in pregnancy. As the tiny, dividing cell mass, the blastocyst, travels from the oviduct and lodges in the wall of the uterus, the cells must exit their pre-implantation state and be ready for post-implantation development.

7 Feb 2019

Largest description of ST3GAL5 deficiency combined using data from 104 individuals

Researchers have combined the largest description of ST3GAL5 deficiency using detailed natural history data from 104 individuals of Amish ancestry born between 1986 and 2017 with a definite or probable diagnosis of ST3GAL5 deficiency.

6 Feb 2019

Cannabinoid compounds may reduce viability of colon cancer cells

Medical marijuana has gained attention in recent years for its potential to relieve pain and short-term anxiety and depression. Now, Penn State College of Medicine researchers say some cannabinoid compounds may actually inhibit the growth of colon cancer cells in the lab.

6 Feb 2019

Drug treating breast cancer may be effective in treating lung and ovarian cancer

Two new papers, published simultaneously in Nature Communications and led by researchers at McGill University, offer promise that a drug currently used to treat estrogen positive breast cancer may be effective in treating two different types of cancer, one rare and one common form.

5 Feb 2019

Newly launched CINECA enables researchers to access clinical research data

Registered researchers will have rapid access to an "unprecedented scale" of clinical research data through the new Common Infrastructure for National Cohorts in Europe, Canada and Africa, launched today.

4 Feb 2019

OU researcher and collaborators are developing new strategies for early intervention of Lupus

A University of Oklahoma researcher, Si Wu, and collaborators from the Oklahoma Medical Research Foundation and Indiana University, are developing new strategies leading to diagnosis and early intervention of Lupus, an autoimmune disease that may affect up to 1.5 million Americans.

1 Feb 2019

Researchers call for industry standards to help improve high-throughput genomic sequencing

Researchers from the George Washington University, the U.S. Food and Drug Administration, and industry leaders published in PLOS Biology, describing a standardized communication method for researchers performing high-throughput sequencing called BioCompute.

31 Jan 2019

FSU study breaks new ground in the battle against malignant pediatric brain cancers

Scientists are making important progress in the battle against a class of devilishly complex human pediatric brain cancers thanks to a new study from a team of Florida State University students and faculty.

30 Jan 2019

New drug compounds show promise in treating acute myeloid leukemia

Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one of the most lethal cancers. About 19,520 news cases are diagnosed a year, and about 10,670 people a year die from it, according to the American Cancer Society.

29 Jan 2019

New study solves mystery behind how proteins interact with cell membrane

Trillions of cells -- all different shapes and sizes -- form a human body's structure. Surrounding each cell is a membrane, jointly acting as hostess and security -- welcoming certain information into the cell while making sure its components don't spill out into the body's void.

25 Jan 2019

Biochemistry News and Research

New method detects potentially disease-causing forms of proteins using fluorescence

Study discovers new therapy for aggressive blood cancer

Cell membrane complexes may be new target for drugs to kill cancer cells

Marine snail venom reveals clues to developing faster-acting insulin for diabetic patients

Newly discovered genetic disorder opens way for future diabetes drugs

Frequency of heteroresistance has been greatly underestimated, study finds

Research sheds light on how motor enzyme can promote genome integrity

Researchers identify genes that make Staphyloccocus bacteria resistant to treatment

When genomic sequencing fails to diagnose a rare disease

Metabolic plasticity helps metastatic cancer cells survive hostile environments

Mutations in folliculin gene affect embryo implantation

Largest description of ST3GAL5 deficiency combined using data from 104 individuals

Cannabinoid compounds may reduce viability of colon cancer cells

Drug treating breast cancer may be effective in treating lung and ovarian cancer

Newly launched CINECA enables researchers to access clinical research data

OU researcher and collaborators are developing new strategies for early intervention of Lupus

Researchers call for industry standards to help improve high-throughput genomic sequencing

FSU study breaks new ground in the battle against malignant pediatric brain cancers

New drug compounds show promise in treating acute myeloid leukemia

New study solves mystery behind how proteins interact with cell membrane

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