Vascular News and Research

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Study may pave the way for mechano-medical approaches to treating abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) is a complex and life-threatening vascular disease with high incidence worldwide. Termed the silent killer, most AAAs are asymptomatic, often going undetected until rupture, and involve a poorly understood set of mechanical and biochemical events.

28 Jan 2022

New atlas characterizes immune cells that play a role in hemorrhagic stroke

In work that will enhance the study of such disparate diseases as stroke and dementia, researchers at UC San Francisco have catalogued all the cells that form the blood vessels of the human brain, along with their locations and the genes transcribed in each.

28 Jan 2022

Updated analysis helps clarify the relationship between alcohol consumption and epilepsy

Epilepsy, a common neurological disorder associated with stigma, psychiatric comorbidities, and rising healthcare costs, affects approximately 50 million people globally. A common risk factor associated with the development of epilepsy and seizures is alcohol consumption.

28 Jan 2022

Higher social determinants of health burden linked to increase in obesity

Cumulative social disadvantage, as denoted by higher social determinants of health (SDOH) burden, is associated with a higher likelihood of obesity independent of clinical and demographic factors, according to a new study in Obesity, The Obesity Society's (TOS) flagship journal.

27 Jan 2022

Following heart-healthy lifestyle behaviors can support good brain health

The same risk factors that contribute to making heart disease the leading cause of death worldwide also impact the rising global prevalence of brain disease, including stroke, Alzheimer's disease and dementia, according to the American Heart Association's Heart Disease and Stroke Statistics - 2022 Update, published today in the Association's flagship, peer-reviewed journal Circulation.

27 Jan 2022

Breast cancer drug shows promise in treating young infants with PIK3CA-related overgrowth spectrum

PIK3CA-related overgrowth spectrum (PROS) is a group of rare, incurable disorders caused by mutations in the PIK3CA gene that result in the malformation and overgrowth of various parts of the body.

26 Jan 2022

AI system can analyze eye scans to identify patients at high risk of heart attack

Scientists have developed an artificial intelligence (AI) system that can analyze eye scans taken during a routine visit to an optician or eye clinic and identify patients at a high risk of a heart attack.

25 Jan 2022

Peptide-enhanced antibody therapy may help treat breast cancer metastasis to bone

A moderate amount of a peptide-enhanced, biological cancer drug goes a long way in treating breast cancers that metastasize to the bone.

24 Jan 2022

Blood proteins could be potential targets for future drugs to slow aging process

Two blood proteins have been shown by scientists to influence how long and healthy a life we live, research suggests.

24 Jan 2022

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)."

24 Jan 2022

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Researchers published a study exploring the possibilities of predisposing men for a life-threatening disease course of COVID-19.

24 Jan 2022

Study examines how elimination of race-based adjustments in kidney function estimates impacts clinical trials

Considerable controversy surrounds race-based algorithms in medicine - such as an adjustment for Black race in equations that estimate individuals' kidney function. A new study in CJASN has examined the impact of changes to these equations on the inclusion of Black participants in kidney disease–related clinical trials, and on the results of such trials.

24 Jan 2022

Genetic marker linked to higher risk of death in COVID-19 patients

A new study discusses the importance of single nucleotide polymorphisms in the Rab46 gene as a marker of adverse outcomes in high-risk COVID-19 patients.

23 Jan 2022

New MRI technology to expand imaging access for patients with implanted medical devices and obesity

New MRI technology, developed by Siemens in collaboration with researchers at The Ohio State University College of Medicine and College of Engineering, will expand imaging access for patients with implanted medical devices, severe obesity and claustrophobia.

21 Jan 2022

Patients likely to experience inappropriate shocks from defibrillators without firmware update

A case study of a patient who experienced inappropriate shocks from her defibrillator is presented in Heart Rhythm Case Reports, an official journal of the Heart Rhythm Society, published by Elsevier.

20 Jan 2022

Could heart rate be a risk factor for dementia?

In this interview, we speak to Dr. Yume Imahori about her latest research which looks at whether heart rate could be used as an early risk factor for dementia.

20 Jan 2022

'Retinal age gap' can be an independent predictor of increased mortality risk

The difference between the biological age of the retina, the light sensitive layers of nerve tissue at the back of the eye, and a person's real (chronological) age, is linked to their risk of death, finds research published online in the British Journal of Ophthalmology.

19 Jan 2022

Study provides insights into how SARS-CoV-2 impacts the brain

Some patients who develop new cognitive symptoms after a mild bout of COVID have abnormalities in their cerebrospinal fluid similar to those found in people with other infectious diseases.

18 Jan 2022

Subcutaneous nanotherapy can make immunomodulation more effective in people with type 1 diabetes

Individuals living with type 1 diabetes must carefully follow prescribed insulin regimens every day, receiving injections of the hormone via syringe, insulin pump or some other device. And without viable long-term treatments, this course of treatment is a lifelong sentence.

18 Jan 2022

Study: Nearly 30% of people with blinding retinal disease can safely stop eye injection therapy

In a preliminary study of 106 people with "wet" age-related macular degeneration, Johns Hopkins Medicine researchers report that as many as a third of those with the blinding retinal disease may someday be able to safely stop eye injection therapy without further vision loss.

18 Jan 2022

Vascular News and Research

Study may pave the way for mechano-medical approaches to treating abdominal aortic aneurysm

New atlas characterizes immune cells that play a role in hemorrhagic stroke

Updated analysis helps clarify the relationship between alcohol consumption and epilepsy

Higher social determinants of health burden linked to increase in obesity

Following heart-healthy lifestyle behaviors can support good brain health

Breast cancer drug shows promise in treating young infants with PIK3CA-related overgrowth spectrum

AI system can analyze eye scans to identify patients at high risk of heart attack

Peptide-enhanced antibody therapy may help treat breast cancer metastasis to bone

Blood proteins could be potential targets for future drugs to slow aging process

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Study examines how elimination of race-based adjustments in kidney function estimates impacts clinical trials

Genetic marker linked to higher risk of death in COVID-19 patients

New MRI technology to expand imaging access for patients with implanted medical devices and obesity

Patients likely to experience inappropriate shocks from defibrillators without firmware update

Could heart rate be a risk factor for dementia?

'Retinal age gap' can be an independent predictor of increased mortality risk

Study provides insights into how SARS-CoV-2 impacts the brain

Subcutaneous nanotherapy can make immunomodulation more effective in people with type 1 diabetes

Study: Nearly 30% of people with blinding retinal disease can safely stop eye injection therapy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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