Research News and Research

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Chronic stress may speed up the onset of skin cancer

Does stress speed up the onset of skin cancer? The answer, in mice anyway, appears to be "yes." Scientists at the Johns Hopkins Kimmel Cancer Center say that chronic stress may speed up the process in those at high-risk for the disease.

8 Dec 2004

Wide angle X-ray scattering (WAXS) could help produce lead drugs for disease therapy

Structural changes in proteins can now be seen in increased detail, using a new application of an existing technique. The application, developed at the U.S. Department of Energy's Argonne National Laboratory, could help produce lead drugs for disease therapy.

8 Dec 2004

Need to correct racial disparities in health

The number of lives saved by medical advances over the last 10 years is far outdistanced by the number of lives lost to racial disparities in health status, according to a Virginia Commonwealth University family medicine and public health physician.

8 Dec 2004

Study of safety issues surrounding the medical use of cannabis has just been launched

A first-of-its-kind study of safety issues surrounding the medical use of cannabis has just been launched. Known as the COMPASS study (Cannabis for the management of pain: assessment of safety study), the research initiative will follow 1400 chronic pain patients, 350 of whom use cannabis as part of their pain management strategy, for a one-year period.

8 Dec 2004

Shorter hospice enrollment was linked to elevated depression among family caregivers

Delayed enrollment in hospice can result in increased depression among family members after the death of their loved one, according to a study by Yale researchers published in the American Journal of Psychiatry.

8 Dec 2004

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

An international consortium of scientists lead by Dr. James Paulson of The Scripps Research Institute has created a technology that will advance our understanding of the role of complex sugar chains (glycans or carbohydrates) that decorate the surface of cells in the body.

8 Dec 2004

Greater risk of heart attack associated with Vioxx than Celebrex

In the first epidemiological study designed and executed specifically to determine the heart-attack risk associated with COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex), researchers at the University of Pennsylvania School of Medicine found a greater risk of heart attack associated with Vioxx than Celebrex, although neither of the two drugs showed a statistically significant elevated risk of heart attack relative to people who did not use the drugs.

8 Dec 2004

Helping to heal complications from spinal cord injury

A London scientist has received a major grant to help improve the quality of life for individuals with spinal cord injuries.

8 Dec 2004

Study supports the use of the internal mammary artery in coronary artery bypass grafting

Long-term follow up with heart bypass patients treated in Veterans Affairs hospitals shows that 85 percent of left internal mammary artery grafts and 61 percent of vein grafts remain open (patent) after 10 years, and that these grafts are more likely to offer long-term success when they are attached to larger arteries on the heart, according to a new study in the Dec. 7, 2004 issue of the Journal of the American College of Cardiology.

8 Dec 2004

New malaria enzyme laid bare with help of computer calculations

Using only computers, a research team at Uppsala University in Sweden has managed to reveal both the structure and the function of a newly discovered enzyme from the most dangerous malaria parasite, Plasmodium falciparum.

8 Dec 2004

Lilly launches publicly available clinical trial registry

Eli Lilly and Company today will announce the launch of its publicly available clinical trial registry, www.lillytrials.com, which will post the results from all Phase I through Phase IV clinical trials of Lilly's marketed products.

8 Dec 2004

HHS purchases 1.2 million doses of GSK's Fluarix flu vaccine

HHS Secretary Tommy G. Thompson has announced that the Food and Drug Administration authorized the use of GlaxoSmithKline influenza vaccine, Fluarix, in the United States under an Investigational New Drug application.

8 Dec 2004

Trimming fat overcomes one of the major obstacles to drug design

Biochemists at Ohio State University and their colleagues have overcome one of the major obstacles to drug design, by trimming some of the fat from a molecular sponge that scientists use to study proteins.

8 Dec 2004

Teen-agers suffering from bulimia may also be struggling with a chronic form of depression

Teen-agers suffering from bulimia may in fact be fighting a two-front war, coping with the effects of a devastating eating disorder while struggling with a chronic form of depression, reveals research by Texas A&M University psychologist Marisol Perez

8 Dec 2004

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

"All cancers are marked by some form of DNA replication gone awry, so a basic understanding of DNA replication is of paramount importance to those designing cancer-fighting drugs,"

8 Dec 2004

Resveratrol antioxidant found in red wine may benefit heart tissue

New research on rat heart cells suggests that a well-known antioxidant found in red wine, called resveratrol, may benefit heart tissue by limiting the effects of a condition called cardiac fibrosis.

8 Dec 2004

Defect in one of nature's oldest proteins may be an underlying cause in human miscarriages

University of Rochester scientists studying a vital protein called Serum Response Factor (SRF) in mice have learned new and unexpected facts about SRF's role in early cardiovascular development, and how a defect in this gene may be an underlying cause in human miscarriages.

8 Dec 2004

Thiazolidinedione (TZD) class of anti-diabetic drugs may be a potential targeted therapy for myeloma patients

In laboratory tests on multiple myeloma cells, University of Rochester researchers found that this type of cancer expresses a protein that makes it an easy target for an existing class of diabetes drugs. After more investigation, they hope the discovery will lead to a new, targeted therapy for myeloma patients.

8 Dec 2004

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Using hairlike microelectrodes and computer analysis, neurobiologists at Duke University Medical Center have demonstrated that they can see the detailed instant-to-instant electrical "brainscape" of neural activity across a living brain.

8 Dec 2004

Patients and GPs agree on out of hours care

New research published today (Wednesday 8 December 2004) by DPP: Developing Patient Partnerships shows that high quality care and good access to health professionals are key concerns for both patients and GPs.

8 Dec 2004

Research News and Research

Chronic stress may speed up the onset of skin cancer

Wide angle X-ray scattering (WAXS) could help produce lead drugs for disease therapy

Need to correct racial disparities in health

Study of safety issues surrounding the medical use of cannabis has just been launched

Shorter hospice enrollment was linked to elevated depression among family caregivers

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

Greater risk of heart attack associated with Vioxx than Celebrex

Helping to heal complications from spinal cord injury

Study supports the use of the internal mammary artery in coronary artery bypass grafting

New malaria enzyme laid bare with help of computer calculations

Lilly launches publicly available clinical trial registry

HHS purchases 1.2 million doses of GSK's Fluarix flu vaccine

Trimming fat overcomes one of the major obstacles to drug design

Teen-agers suffering from bulimia may also be struggling with a chronic form of depression

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

Resveratrol antioxidant found in red wine may benefit heart tissue

Defect in one of nature's oldest proteins may be an underlying cause in human miscarriages

Thiazolidinedione (TZD) class of anti-diabetic drugs may be a potential targeted therapy for myeloma patients

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Patients and GPs agree on out of hours care

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