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Scientists discover linchpin protein that drives mitochondria's calcium machinery

Mitochondria, those battery-pack organelles that fuel the energy of almost every living cell, have an insatiable appetite for calcium. Whether in a dish or a living organism, the mitochondria of most organisms eagerly absorb this chemical compound.

20 Jun 2011

New insight into progressive supranuclear palsy

There are new genetic clues on risk factors and biological causes of a rare neurodegenerative disease called progressive supranuclear palsy (PSP), according to a new study from an international genetics team led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

20 Jun 2011

Short warm-ups permit greater cycling performance

Coaches, physiologists and athletes alike will attest to the importance of warming up before athletic competition. Warming up increases muscle temperature, accelerates oxygen uptake kinetics and increases anaerobic metabolism, all of which enhance performance.

18 Jun 2011

Patients still being enrolled in clinical trial for new peripheral vascular disease treatment

The first three patients to undergo an investigational surgical procedure for peripheral vascular disease that involves the patient's own stem cells continue to do well, reports the University of Louisville surgeon who is the principal investigator.

18 Jun 2011

Sunshine enters Adva-27a cancer research and development agreement with The Jewish General Hospital

Sunshine Biopharma, Inc. a development stage pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it has executed an agreement with The Jewish General Hospital, one of McGill University's Hospital Centers, to conduct the necessary research and development to advance Sunshine's lead compound, Adva-27a, through the various stages of preclinical studies and Phase I clinical trials.

17 Jun 2011

Precisely mapped allosteric binding site will facilitate design of drugs with minimal side effects

Structural biologists at Cold Spring Harbor Laboratory (CSHL) have obtained a precise molecular map of the binding site for an allosteric inhibitor in a subtype of the NMDA (N-methyl-D-aspartate) receptor, which is commonly expressed in brain cells.

17 Jun 2011

Innovative adult stem cell approach could help eliminate obesity

Innovative adult stem cell research by scientists at The University of Texas Health Science Center at Houston could aid efforts to apply the brakes to stem cells that produce the type of fat ringing the waists of millions. Research appeared today online ahead of the print issue of Cell Stem Cell.

17 Jun 2011

Snack-based diet can increase risk of obesity

A high-fat diet can be bad for your health. However, a snack-based "cafeteria"-style diet of highly palatable, energy-dense foods is even worse, according to new research.

17 Jun 2011

UTHealth receives $1M FEMA grant to examine link between Ad-36 infection, obesity

Researchers at The University of Texas Health Science Center at Houston (UTHealth) have been awarded nearly $1 million to investigate Adenovirus-36 (Ad-36) infection as a novel risk factor for obesity.

17 Jun 2011

Scientists uncover how immune system responds to invading anthrax bacteria

Scientists at the University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have uncovered how the body's immune system launches its survival response to the notorious and deadly bacterium anthrax.

17 Jun 2011

Anxiety hinders detection during search for multiple objects

A person scanning baggage or X-rays stands a better chance of seeing everything they're searching for if they aren't feeling anxious, according to a new laboratory experiment.

17 Jun 2011

New weapon in the fight against cancer

A cancer diagnosis is not necessarily a death sentence. There are now quite a number of possibilities to treat cancer. In addition to radiotherapy and chemotherapy, so-called radionuclide treatment has also become an important component in the fight against the mutated cells. It involves injecting radioactive elements, so-called nuclides, into the patient's circulatory system.

17 Jun 2011

First genetic, biochemical tests for Idiopathic Infantile Hypercalcemia

A breakthrough in genetic research has uncovered the defect behind a rare hereditary children's disease that inhibits the body's ability to break down vitamin D. This discovery has led researchers to develop the first genetic and biochemical tests that positively identify the disease.

17 Jun 2011

New Australian drug shows positive response in patients with multiple myeloma blood cancer

Australian monoclonal antibody company, Immune System Therapeutics Limited (IST), today announced it would double patient recruitment in its Phase II trial for a breakthrough antibody treatment for terminal blood cancer.

16 Jun 2011

Researchers reveal why anti-androgen therapy may fail in men with prostate cancer

Cancer is crafty. When one avenue driving its growth is blocked by drugs targeting that path, the malignancy often creates a detour, finding an alternative route to get around the roadblock.

16 Jun 2011

University of Houston chemist develops two different materials against E. coli

A University of Houston (UH) chemist who is developing materials for detecting and repelling E. coli has published papers in two high-impact journals this month.

16 Jun 2011

DiagnoCure receives new U.S. patent for PCA3 prostate cancer biomarker portfolio

DiagnoCure, Inc., a life sciences company commercializing high‐value cancer diagnostic tests and delivering laboratory services, today reported the issuance of a new U.S. patent, which represents a significant addition to DiagnoCure's PCA3 prostate cancer biomarker portfolio.

16 Jun 2011

Platelet Derived Growth Factor Receptor-beta plays key role in onset of obesity

A new study from Mount Sinai School of Medicine has found that a cellular signaling pathway governs the differentiation of cells into fat tissue or smooth muscle, which lines the vascular system. Engaging this signaling pathway and its capacity to govern cell differentiation has important implications in preventing obesity and cardiovascular disease.

16 Jun 2011

Cambridge Biomedical, Neogenix partner to develop ELISA assays for pancreatic and colorectal cancer

Neogenix Oncology, Inc. is pleased to announce it has signed an agreement with Cambridge Biomedical, Inc, based in Boston, MA, for the development of its pancreatic and colorectal cancer diagnostic serum ELISA assays.

16 Jun 2011

ISSCR honors UCSF cancer scientist with 2011 Outstanding Young Investigator Award

UCSF's Robert Blelloch, MD, PhD, has received the 2011 Outstanding Young Investigator Award from the International Society for Stem Cell Research, for his pioneering research on the role of molecular tools known as microRNAs in embryonic stem cells and cancer.

16 Jun 2011

Laboratory News and Research

Scientists discover linchpin protein that drives mitochondria's calcium machinery

New insight into progressive supranuclear palsy

Short warm-ups permit greater cycling performance

Patients still being enrolled in clinical trial for new peripheral vascular disease treatment

Sunshine enters Adva-27a cancer research and development agreement with The Jewish General Hospital

Precisely mapped allosteric binding site will facilitate design of drugs with minimal side effects

Innovative adult stem cell approach could help eliminate obesity

Snack-based diet can increase risk of obesity

UTHealth receives $1M FEMA grant to examine link between Ad-36 infection, obesity

Scientists uncover how immune system responds to invading anthrax bacteria

Anxiety hinders detection during search for multiple objects

New weapon in the fight against cancer

First genetic, biochemical tests for Idiopathic Infantile Hypercalcemia

New Australian drug shows positive response in patients with multiple myeloma blood cancer

Researchers reveal why anti-androgen therapy may fail in men with prostate cancer

University of Houston chemist develops two different materials against E. coli

DiagnoCure receives new U.S. patent for PCA3 prostate cancer biomarker portfolio

Platelet Derived Growth Factor Receptor-beta plays key role in onset of obesity

Cambridge Biomedical, Neogenix partner to develop ELISA assays for pancreatic and colorectal cancer

ISSCR honors UCSF cancer scientist with 2011 Outstanding Young Investigator Award

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