Laboratory News and Research

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Research roundup: Use of high-deductible plans limits some E.R. visits; older folks not as sick as they used to be

One-third of US workers now have high-deductible health plans, and those numbers are expected to grow in 2014 as implementation of the Affordable Care Act continues. There is concern that high-deductible health plans might cause enrollees of low socioeconomic status to forgo emergency care as a result of burdensome out-of-pocket costs.

12 Aug 2013

Dopamine responses to alcohol ingestion may serve as marker of vulnerability to AUDs

There are two traits closely associated with the development of alcohol use disorders (AUDs). One is a lower subjective intoxication response, also known as a low level of response to alcohol.

12 Aug 2013

Shape and meaning: A study explores how brain encodes visual objects

Opening our eyes and seeing the world before us, full of objects, is a simple action we may take for granted. Yet our brain is constantly carrying out a huge analysis only to let us see a flower, a pen, the face of our children.

12 Aug 2013

Neuroscientists discover protein associated with Alzheimer's Disease

A team of neuroscientists has identified a modification to a protein in laboratory mice linked to conditions associated with Alzheimer's Disease. Their findings, which appear in the journal Nature Neuroscience, also point to a potential therapeutic intervention for alleviating memory-related disorders.

12 Aug 2013

Cigarette taxation reduces alcohol consumption among vulnerable groups

Tobacco use is the leading cause of preventable death and disability in the U.S., while heavy drinking ranks as the third leading cause of preventable death. Cigarette taxation has been recognized as one of the most significant policy instruments to reduce smoking.

12 Aug 2013

Specialized endocytocis play a crucial role in shaping cells themselves

The process cells use to 'swallow' up nutrients, hormones and other signals from their environment - called endocytosis - can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found.

12 Aug 2013

The Estate of Charles Meixner awards $3M to Autism Speaks to discover treatments for ASD

Autism Speaks, the world's leading autism science and advocacy organization, today announced that the estate of Charles Meixner has donated $3 million to support Autism Speaks' Translational Research Initiative in the hopes of accelerating the discovery of treatments for autism spectrum disorder (ASD).

12 Aug 2013

Tubingen researchers resolve how a plant steroid hormone makes plants grow

If one wants to better understand how plants grow, one must analyse the chemistry of life in its molecular detail. Michael Hothorn from the Friedrich-Miescher-Laboratory of the Max Planck Society in T-bingen and his team are doing just that. Their latest work now reveals that a plant membrane receptor requires a helper protein to sense a growth-promoting steroid hormone and to transduce this signal across the cell membrane.

9 Aug 2013

Research suggests blocking DNA repair complex helps fight therapy-resistant leukemia

New research posted online by the Nature journal Leukemia suggests blocking part of a DNA repair complex that helps some types of leukemia resist treatment can increase the effectiveness of chemotherapy and enhance survival.

9 Aug 2013

Study: Immune-regulating molecules can trigger lymphomas

A small group of immune-regulating molecules, when overproduced even moderately, can trigger the blood cancers known as lymphomas, according to a new study led by scientists from The Scripps Research Institute (TSRI).

9 Aug 2013

Children born by Caesarean section more vulnerable to allergies

Children who came into the world by Caesarean section are more often affected by allergies than those born in the natural way. The reason for this may be that they have a less diverse gut microbiota, according to a study by universities in Sweden and Scotland.

9 Aug 2013

New reagent kits for intracellular staining from Beckman Coulter Life Sciences

PerFix-Expose1 and PerFix-nc1, innovative new reagent kits for intracellular staining from Beckman Coulter Life Sciences, minimize sample manipulation for a streamlined workflow that delivers high quality results. Developed for use on Beckman Coulter’s Gallios1 and Navios2 series flow cytometers and compatible with all Beckman Coulter Life Sciences’ fluorochromes, the kits enable a clear focus on the cytoplasmic and nuclear compartments of the cell.

8 Aug 2013

High mobility group (HMG) genes and cancer: an interview with Dr. Linda Resar, Johns Hopkins University School of Medicine

High mobility group A genes are highly expressed in all aggressive cancers studied to date. These genes encode the high mobility group A (HMGA) proteins. In other words, these genes provide the genetic “code” necessary to produce HMGA proteins.

8 Aug 2013

Findings could lead to development of therapeutic agents for age-related diseases

Scientists at Sanford-Burnham Medical Research Institute have identified a key factor that regulates the autophagy process, a kind of cleansing mechanism for cells in which waste material and cellular debris is gobbled up to protect cells from damage, and in turn, modulates aging.

8 Aug 2013

Cognitive decline with age is natural part of life, OSU researchers find

If you forget where you put your car keys and you can't seem to remember things as well as you used to, the problem may well be with the GluN2B subunits in your NMDA receptors.

8 Aug 2013

Intervention program to disruptive kids can prevent substance use in adolescence

Delivering a two-year intervention programme to disruptive kindergarten children could help prevent substance use in adolescence, according to a new study published in the British Journal of Psychiatry.

8 Aug 2013

TSRI scientists decode important molecular signal that guides development of neocortex

Scientists at The Scripps Research Institute have decoded an important molecular signal that guides the development of a key region of the brain known as the neocortex. The largest and most recently evolved region of the brain, the neocortex is particularly well developed in humans and is responsible for sensory processing, long-term memory, reasoning, complex muscle actions, consciousness and other functions.

8 Aug 2013

Laboratory News and Research

Research roundup: Use of high-deductible plans limits some E.R. visits; older folks not as sick as they used to be

Dopamine responses to alcohol ingestion may serve as marker of vulnerability to AUDs

Shape and meaning: A study explores how brain encodes visual objects

Neuroscientists discover protein associated with Alzheimer's Disease

Cigarette taxation reduces alcohol consumption among vulnerable groups

Specialized endocytocis play a crucial role in shaping cells themselves

The Estate of Charles Meixner awards $3M to Autism Speaks to discover treatments for ASD

Tubingen researchers resolve how a plant steroid hormone makes plants grow

Research suggests blocking DNA repair complex helps fight therapy-resistant leukemia

Study: Immune-regulating molecules can trigger lymphomas

Children born by Caesarean section more vulnerable to allergies

New reagent kits for intracellular staining from Beckman Coulter Life Sciences

High mobility group (HMG) genes and cancer: an interview with Dr. Linda Resar, Johns Hopkins University School of Medicine

Findings could lead to development of therapeutic agents for age-related diseases

Cognitive decline with age is natural part of life, OSU researchers find

Intervention program to disruptive kids can prevent substance use in adolescence

TSRI scientists decode important molecular signal that guides development of neocortex

High-tech laser technique offers control of gene therapy and genetic engineering method

Scientists identify important molecular signal that guides development of brain

Cancer-linked mitosis: an interview with Professor Scott Kern, Johns Hopkins University School of Medicine

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