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Researchers find better way to purify liver cells made from induced pluripotent stem cells

A research team including developmental biologist Stephen A. Duncan, D. Phil., SmartState Chair of Regenerative Medicine at the Medical University of South Carolina, has found a better way to purify liver cells made from induced pluripotent stem cells (iPSCs).

30 Aug 2016

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

In microseconds, every light ray that enters the eye triggers an explosion of coordinated cellular events.

29 Aug 2016

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researchers at the National Center for Advancing Translational Sciences recently identified compounds that potentially can be used to inhibit Zika virus replication and reduce its ability to kill brain cells.

29 Aug 2016

Studying mutant peptides may help detect weaknesses in tumor cells

Researchers from MIPT, the Institute of Biomedical Chemistry, the Institute for Energy Problems of Chemical Physics, and the Research Institute of Physico-Chemical Medicine have presented an algorithm to detect mutant proteins based on mass spectrometry data and the results of exome sequencing.

29 Aug 2016

$Lipoprotein apheresis may have new role in patients with refractory angina$

Lipoprotein apheresis may have new role in patients with refractory angina

Initial investigation of patients with suspected coronary heart disease (CHD) using functional imaging - rather than guideline-directed care - resulted in significantly less unnecessary angiography, according to results of the CE-MARC 2 trial.

29 Aug 2016

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

BRAF mutation occurs in between 40% and 50% of metastasising melanomas (skin cancers), boosting tumour growth.

29 Aug 2016

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

Janssen-Cilag International NV has announced the submission of a Type II variation application to the European Medicines Agency (EMA), seeking to broaden the existing marketing authorisation for the immunotherapy DARZALEX® (daratumumab) to include treatment of adult patients with relapsed multiple myeloma who have received at least one prior therapy. The expanded indication is based on daratumumab in combination with lenalidomide (an immmunomodulatory agent) and dexamethasone, or bortezomib (a PI) and dexamethasone.

29 Aug 2016

New test may help detect Parkinson's disease in early stages of illness

A test that can detect Parkinson's disease in the early stages of the illness has moved a step closer.

28 Aug 2016

Sanford-NDSU Collaborative Seed Grant Program provides funding for three health research projects

Three research projects have received $250,000 in seed funding from the Sanford Health NDSU Collaborative Seed Grant program. NDSU researchers will have opportunities to collaborate with investigators from Sanford Research.

28 Aug 2016

UT Southwestern researchers identify protein that can kick-start more efficient, healthful breakdown of fat

Researchers at UT Southwestern Medical Center have found that a protein often located on the surface of fat droplets within cells - and especially abundant in the muscles of endurance athletes - can kick-start the more efficient and healthful breakdown of fat.

27 Aug 2016

Penn State dermatologist clarifies common myths about psoriasis

Psoriasis is a much-misunderstood disease, often kept under wraps by sufferers who want to hide their skin lesions.

26 Aug 2016

Fiocruz to start phase II clinical trials of novel vaccine for schistosomiasis

The Oswaldo Cruz Foundation at Rio de Janeiro, Brazil, will start the phase II clinical trials of a vaccine for schistosomiasis, called 'Sm14 Vaccine'.

26 Aug 2016

Researchers find new way for early prediction of leukemic relapse

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer.

26 Aug 2016

Researchers engineer protein-shelled nanostructures useful for ultrasound imaging

Ultrasound imaging is used around the world to help visualize developing babies and diagnose diseases. Sound waves bounce off the tissues, revealing their different densities and shapes.

26 Aug 2016

Hitchhiking of drugs on incorrect targets can cause adverse side effects

It probably isn't surprising to read that pharmaceutical drugs don't always do what they're supposed to. Adverse side effects are a well-known phenomenon and something many of us will have experienced when taking medicines.

26 Aug 2016

Chromatrap develops new range of optimised ChIP assay kits for genetic research

Chromatrap is a pioneer in the development of solid-state filter-based technology that significantly enhances and accelerates the important epigenetic research tool of chromatin immunoprecipitation (ChIP).

From Chromatrap® - Porvair Sciences Ltd 26 Aug 2016

Study finds age-dependent differences in expression of allergy to dust mites

In adults with a house dust mite allergy, a cascade of inflammatory signals on the surface of the airways leads to airway remodeling.

26 Aug 2016

TSRI study sheds light on how mitochondrial calcium can affect learning and memory

While calcium's importance for our bones and teeth is well known, its role in neurons—in particular, its effects on processes such as learning and memory—has been less well defined.

26 Aug 2016

New biomaterial allows scientists to study how stem cells sense stiffness of surrounding environment

A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment, found a team led by Robert Mauck, PhD, the Mary Black Ralston Professor for Education and Research in Orthopaedic Surgery, in the Perelman School of Medicine at the University of Pennsylvania.

26 Aug 2016

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive.

26 Aug 2016

G Protein News and Research

Researchers find better way to purify liver cells made from induced pluripotent stem cells

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Studying mutant peptides may help detect weaknesses in tumor cells

Lipoprotein apheresis may have new role in patients with refractory angina

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

New test may help detect Parkinson's disease in early stages of illness

Sanford-NDSU Collaborative Seed Grant Program provides funding for three health research projects

UT Southwestern researchers identify protein that can kick-start more efficient, healthful breakdown of fat

Penn State dermatologist clarifies common myths about psoriasis

Fiocruz to start phase II clinical trials of novel vaccine for schistosomiasis

Researchers find new way for early prediction of leukemic relapse

Researchers engineer protein-shelled nanostructures useful for ultrasound imaging

Hitchhiking of drugs on incorrect targets can cause adverse side effects

Chromatrap develops new range of optimised ChIP assay kits for genetic research

Study finds age-dependent differences in expression of allergy to dust mites

TSRI study sheds light on how mitochondrial calcium can affect learning and memory

New biomaterial allows scientists to study how stem cells sense stiffness of surrounding environment

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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