G Protein News and Research

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Acne-like rash linked to effectiveness of new targeted cancer treatment – cetuximab

Acne is not a condition that anyone would welcome under normal circumstances, but an international study of a new targeted cancer treatment – cetuximab – has shown that patients who developed an acne-like rash responded better to the treatment than those who did not.

30 Sep 2004

Large-scale screening programme of tonsil tissue is the only way of identifying the true incidence of vCJD infection

A study in this week’s issue of THE LANCET describes how two different types of analysis used in conjunction on samples of tonsil tissue is the ‘gold standard’ method for confirming clinical variant CJD

30 Sep 2004

One in five people in the developed world will die of the diseases we call cancer

What they die of is not one disease, but a bewildering array of cancers, each of which behaves differently, grows differently and - crucially - responds to treatment differently.

29 Sep 2004

Cancer vaccine based on listeria bacteria shows promise

An experimental cancer vaccine using defanged listeria bacteria is showing great promise in animal studies, successfully treating new cancers that have spread into the lungs of mice.

29 Sep 2004

Two types of thyroid cancer can be readily identified by differences in only a few genes

Two types of thyroid cancer that are closely related and sometimes difficult to distinguish can be readily identified by differences in only a few genes, new research shows.

29 Sep 2004

Bacterium Haemophilus influenza has to secrete a glue-like protein

To stick to cells in the respiratory tract and start an infection, the bacterium Haemophilus influenza has to secrete a glue-like protein. Researchers at Washington University School of Medicine in St. Louis report this week that a study of the valve that lets out the glue has produced some surprising information.

29 Sep 2004

Studies confirm that chronic kidney disease independently increases the risk of developing cardiovascular disease

A pair of new epidemiology studies confirms that chronic kidney disease independently increases the risk of developing cardiovascular disease, even among people with early kidney disease and after considering other risk factors such as diabetes, hypertension and high cholesterol.

29 Sep 2004

Cancer Research Technology and The Institute of Cancer Research complete licence with Vernalis

Cancer Research Technology Limited (CRT) and The Institute of Cancer Research announce that Vernalis plc has licensed exclusive worldwide rights to an anti-cancer Hsp90 inhibitor programme.

29 Sep 2004

Phase II trials of the first second-generation antisense cancer drug to be used in patients soon to be underway

Phase II trials of the first second-generation antisense cancer drug to be used in patients are soon to be underway in the wake of a successful Phase I study, which has demonstrated that the new drug blocks its target gene in exactly the way it is designed to do.

28 Sep 2004

Arsenic trioxide - invented as a treatment for a rare type of leukaemia

Arsenic trioxide – a highly poisonous substance best known as an effective weed killer or pesticide and notorious for being a favourite ‘weapon’ of choice in murder mystery novels, is being re-invented as a treatment for a rare type of leukaemia.

28 Sep 2004

Microfluidics help lab-on-a-chip development skyrocket

Lab-on-a-chip (LOC) development has skyrocketed in the last couple of years due to constant efforts in harnessing microfluidics and µTAS to improve the LOC design and function. The distinct advantages that they bestow on applications are pushing the commercial potential of LOCs.

28 Sep 2004

Duplication of the alpha-synuclein gene causes Parkinson's disease in a French family

In affected individuals, age of onset, symptoms and symptom progression are similar to that observed in people with sporadic or unexplained cases of Parkinson's disease.

27 Sep 2004

Discovery of key molecular step which allows cancer cells to move to different parts of the body

Researchers at The University of Texas M. D. Anderson Cancer Center have figured out a key molecular step by which a cancer cell can unhook itself from the mesh weave of other cancer cells in a tumor, and move away to a different part of the body - the process, known as metastasis, that makes cancer so dangerous.

27 Sep 2004

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Researchers targeted Nef, a protein responsible for accelerating the development of acquired immunodeficiency syndrome, or AIDS. Nef was targeted with small molecules synthesized by the researchers – molecules that disrupted Nef’s interaction with other proteins.

26 Sep 2004

G Protein News and Research

Acne-like rash linked to effectiveness of new targeted cancer treatment – cetuximab

Large-scale screening programme of tonsil tissue is the only way of identifying the true incidence of vCJD infection

One in five people in the developed world will die of the diseases we call cancer

Cancer vaccine based on listeria bacteria shows promise

Two types of thyroid cancer can be readily identified by differences in only a few genes

Bacterium Haemophilus influenza has to secrete a glue-like protein

Studies confirm that chronic kidney disease independently increases the risk of developing cardiovascular disease

Cancer Research Technology and The Institute of Cancer Research complete licence with Vernalis

Phase II trials of the first second-generation antisense cancer drug to be used in patients soon to be underway

Arsenic trioxide - invented as a treatment for a rare type of leukaemia

Microfluidics help lab-on-a-chip development skyrocket

Duplication of the alpha-synuclein gene causes Parkinson's disease in a French family

Discovery of key molecular step which allows cancer cells to move to different parts of the body

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Study presents multiple lines of evidence against the proposed link between SV40 and human mesotheliomas

Discovery of how protein in teeth controls bone-like crystals to form steely enamel

Gene responsible for a rare form of dystonia known as rapid-onset dystonia parkinsonism identified

Researcher looks for clues to degenerative, deadly disease called Ataxia-telangiectasia

Terror fears raise women's level of protein linked to heart disease

Breakthrough discovery on why the malaria parasite has become resistant to chloroquine

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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