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New book suggests foods with a low glycemic index are key to weight loss

Choosing foods with a low glycemic index is the key to successful and sustainable weight loss, according to a new book written by nutritionists from the University of Sydney.

23 Sep 2004

New link in the growth of Ewing’s sarcoma

To develop new therapeutic approaches to cancer, it is essential to understand the long and extremely complex process that underlies it, in other words the various stages of cancer development from the initial mutation to the tumor.

23 Sep 2004

Research to halt the progress of chronic liver disease

A University of Queensland researcher is working to halt the progress of chronic liver disease, which affects a quarter of million Australians.

22 Sep 2004

Amyloid growth can occur independently of oligomers

Improperly folded proteins are normally destroyed. But in a wide range of diseases, including prion (from proteinaceous and infectious) diseases and neurodegenerative diseases like Parkinson disease and Alzheimer disease, amyloid fibrils, or plaques--misshapen proteins that aggregate into characteristic ropelike configurations--accumulate in tissue.

22 Sep 2004

Edible vaccine for HIV AIDS

Scientists from Novosibirsk are engaged in the development of an unusual vaccine which, apart from being less expensive to produce, safe and painless to administer, is also edible.

22 Sep 2004

New gene therapy technique may help treat Alzheimer's disease

Investigators at Rush University Medical Center have successfully initiated a new technique that uses gene therapy to deliver nerve growth factor into regions of the brain where neurons are degenerating, in order to prevent cell death and reverse cell atrophy, two hallmarks of Alzheimer's disease.

21 Sep 2004

Novel strategy for stimulating the production of utrophin

Researchers at the University of Pennsylvania School of Medicine report a novel strategy for stimulating the production of utrophin – an important muscle protein in young mice – for muscular dystrophy therapy.

21 Sep 2004

Scientists have corrected a flaw in cancer cells that lets them evade the normal cell-death process

Scientists at Dana-Farber Cancer Institute have corrected a flaw in cancer cells that lets them evade the normal cell-death process, and as a result they eliminated leukemia cells from mice.

21 Sep 2004

Stress response proteins offer a promising target for a novel drug guidance system

Their study, published in the September issue of the journal Cancer Cell, demonstrates how researchers can find protein tags that are unique to cancer cells and then tweak a drug delivery system to zero in on those tags and destroy the cells.

21 Sep 2004

HER-2 cell surface receptors tun on genes associated with carcinogenesis

Researchers at The University of Texas M. D. Anderson Cancer Center now have evidence that receptors found on tumors that were believed to function only on the surface of cells can actually switch on genes inside a cell's nucleus, thus promoting cancer development in two distinct ways.

21 Sep 2004

Certain cancers might one day be cured without the use of toxic chemotherapy and radiation

The eradication of brain tumors in mice following treatment with a novel drug suggests that certain cancers might one day be cured without the use of toxic chemotherapy and radiation.

20 Sep 2004

New anti-inflammatory strategy for cancer therapy

A new strategy for cancer therapy, which converts the tumor-promoting effect of the immune system’s inflammatory response into a cancer-killing outcome, is suggested in research findings by investigators at the University of California, San Diego (UCSD) School of Medicine.

20 Sep 2004

Research may provide a better understanding of the mental retardation observed in Cri-du-Chat Syndrome

By specifically deleting the adhesion protein d-catenin, which is found exclusively in the brain, researchers at UCLA have found evidence that loss of d-catenin produces severe cognitive and synaptic dysfunction.

20 Sep 2004

Scientists unlock the crucial communication pathways of p53 protein cells

Professor Nicholas La Thangue and his team at the Institute of Biomedical and Life Sciences at the University of Glasgow have unlocked the crucial communication pathways of p53 protein cells, which could ultimate aid the slowing down of cells that cause tumours and related disease.

20 Sep 2004

Isis Pharmaceuticals licenses second anti-cancer drug candidate to Lilly

Isis Pharmaceuticals announced today that Eli Lilly and Company licensed LY2275796, a second-generation antisense anti-cancer drug candidate for clinical development.

20 Sep 2004

Resveratrol in red wine, is thought to contribute to improved cardiovascular effects associated with moderate consumption of red wine

Researchers funded by the National Science Foundation (NSF) and affiliated with the Salk Institute in San Diego, Calif., have succeeded in converting chalcone synthase, a biosynthetic protein enzyme found in all higher plants, into an efficient resveratrol synthase.

20 Sep 2004

Protein points to anticancer drug targets

A unique tail at one end of a protein called Ubc12 stabilizes a molecular workshop that assembles the “on-switch cells” used to accelerate cell replication.

20 Sep 2004

Immunoglobulins may help patients with Alzheimer’s

Immunoglobulins which are already being used to treat multiple sclerosis may also be able to help patients with Alzheimer’s. This, at least, is the finding of a pilot study on five patients at the University of Bonn.

20 Sep 2004

Research findings may help stave off full-blown diabetes

A new study by researchers at Joslin Diabetes Center sheds light on the key mechanisms by which new pancreatic beta cells normally form in response to insulin resistance. These findings may some day help researchers devise ways of staving off full-blown diabetes.

18 Sep 2004

Mitomycin C offers limited benefit in reducing unsightly scars

The tendency for extreme scarring is one reason many African Americans avoid plastic surgery and other surgical incisions. Though surgeons continue to develop less invasive techniques that minimize scarring, other options are needed to help these individuals who are prone to developing keloid scars.

17 Sep 2004