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Study may help develop ibrutinib-based combination therapies for blood cancer

Chronic lymphocytic leukemia (CLL) is the most common form of blood cancer (leukemia) in the Western world, affecting approximately 1.2% of all cancer patients.

30 Jan 2020

High intake of dietary flavonols tied to lower risk of Alzheimer's dementia

People who eat or drink more foods with the antioxidant flavonol, which is found in nearly all fruits and vegetables as well as tea, may be less likely to develop Alzheimer's dementia years later, according to a study published in the January 29, 2020, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Jan 2020

Maternal consumption of low-calorie sweeteners alters metabolism, gut microbiota in offspring

Many people turn to artificial or so-called natural sweeteners to cut calories and lose weight. A new study led by Dr. Raylene Reimer, PhD, published in the high-impact journal Gut discovered that the consumption of low-calorie sweeteners while pregnant increased body fat in their offspring and disrupted their gut microbiota - the trillions of bacteria and other microorganisms that inhabit the intestinal tract and affect our health and risk of numerous diseases.

29 Jan 2020

Highly active adults engage in a greater variety of activities to meet exercise guidelines

Highly active adults engage in a greater variety of physical activities than do less active adults, finds a new study led by researchers at NYU Rory Meyers College of Nursing.

29 Jan 2020

Research project moves one step closer to personalized treatment of rheumatic diseases

When a patient is diagnosed with rheumatoid arthritis, psoriatic arthritis or spondyloarthritis, prescribing the correct type of medicine is a case of trial and error.

29 Jan 2020

Mount Sinai cardiologists share tips to prevent and lower risk of cardiac events

Heart disease is the leading cause of death among both men and women in the United States, but according to the American Heart Association, it is preventable 80 percent of the time.

29 Jan 2020

New strategy using organoids to study childhood brain tumors

A new study reports the creation of in vitro models of brain tumors in children using organoids derived from stem cells, which will help to screen new drugs for efficacy and thus improve the rate of drug development. The study, titled 'Modeling medulloblastoma in vivo and with human cerebellar organoids,' is published in the journal Nature Communications.

29 Jan 2020

Finer particulate matter (PM1) and risk of cardiovascular disease

A new study published in the journal Environmental Science & Technology Letters reports that particulate matter smaller than a single micron in diameter, called PM1, is strongly linked to the occurrence of cardiovascular disease (CVD). This is thought to be due to its higher surface area to volume ratio.

29 Jan 2020

Living longer AND living healthy

American Heart Association (AHA) President Robert A. Harrington says that the life expectancy has gone up in recent years. Still, he points out, improved life expectancy doesn’t translate to improved health in all cases. According to him, “Not all those years are healthy ones as the effects of chronic illnesses are increasingly impacting the quality of life of people at a much younger age than in the past.”

29 Jan 2020

Pre-existing anticancer drug could help treat common form of heart failure

When it comes to finding new treatments for disease, reinventing the wheel is not always necessary - drugs already in use for other conditions may do the job.

29 Jan 2020

Shape-shifting cells rush to repair the defect after bone injury

Conventional thinking is that bone regeneration is left to a small number of mighty cells called skeletal stem cells, which reside within larger groups of bone marrow stromal cells.

29 Jan 2020

Dining out is a recipe for unhealthy eating most of the time, study shows

The typical American adult gets one of every five calories from a restaurant, but eating out is a recipe for meals of poor nutritional quality in most cases, according to a new study by researchers at the Friedman School of Nutrition Science and Policy at Tufts University.

29 Jan 2020

New way to treat stroke using an already FDA-approved drug shows promise

Stroke is the third leading cause of death and disability in the United States. More than 87 percent are ischemic strokes, caused by obstruction of one or more cerebral arteries. With limited progress in developing treatments, there is a critical need for neuroprotective agents to effectively treat stroke.

29 Jan 2020

High carbon dioxide levels due to respiratory diseases may aggravate pancreatic cancer

Chronic obstructive pulmonary disease or COPD is associated with higher rates of many cancers, including lung, esophagus, colon, bladder and breast cancer.

29 Jan 2020

Time to include standard care screenings for diagnosis of pre-symptomatic type 1 diabetes

Researchers at Helmholtz Zentrum München employed the world's first early detection test for type 1 diabetes in a large-scale population study in Bavaria, Germany, and investigated its effects.

29 Jan 2020

Diabetes Action Canada develops National Diabetes Repository to aid research

For diabetes researchers across Canada, data from patients is a critical tool in determining what projects will truly make a difference for people living with the disease.

29 Jan 2020

New blood sugar tool could one day replace uncomfortable finger-prick test

Researchers have developed a new way to monitor blood sugar levels that could replace the needle-prick method that people with diabetes currently use.

29 Jan 2020

New goals to help all people live healthier for more years of life

Data reported in the just published American Heart Association's Heart & Stroke Statistics - 2020 Update, show heart disease and stroke deaths continue to decline, but that trend has slowed significantly in recent years.

29 Jan 2020

Researchers develop new strategy to study childhood brain tumors

Researchers are at work to find effective treatments to help young patients with brain tumors. Hundreds of brain organoids have been developed in the laboratories of the University of Trento to understand the genetic mechanisms responsible for these hard to treat diseases.

29 Jan 2020

Study advances the understanding of capillary regression

Many diseases arise from abnormalities in our capillaries, tiny exquisitely branching blood vessel networks that play a critical role in tissue health.

29 Jan 2020