Genetic Engineering News and Research

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Researchers discover new target for human antibodies that holds key to vaccine for dengue

Creating a vaccine that protects people from all four types of dengue virus has frustrated scientists for decades. But researchers at the University of North Carolina have discovered a new target for human antibodies that could hold the key to a vaccine for the world's most widespread mosquito-borne disease.

27 Feb 2014

Goal: Therapies for hearing loss and communications problems

Research scientist Christine Portfors will study how the brain chemical dopamine influences hearing with support from the National Institutes of Health. The work may ultimately lead to better therapies for people with hearing loss and communication problems.

27 Feb 2014

Therapeutic hypothermia may not be effective in all patients who suffered heart attack, says study

Whole body cooling in comatose patients who have suffered a heart attack can limit the damage to brain tissue caused by the restoration of blood flow and oxygen.

26 Feb 2014

Viewpoints: Finding a plan for 'tinkering with DNA'; fact-checking claims of ACA losses; pediatricians' fears of retail clinics

The manipulation of human genes could lead to profound advances in our ability to cure or prevent terrible diseases. But in some cases, it might also mean introducing genetic material that could be passed from one generation to the next, changing the human gene pool in a manner that could inadvertently harm peoples' health.

26 Feb 2014

European Commission invests nearly $475 million in gene transfer and gene therapy projects

Over the past three funding stages, the European Commission has invested nearly $475 million in 100 projects in the gene transfer and gene therapy field.

25 Feb 2014

Study links carbohydrate calorie-rich diets to greater risk for brain shrinkage, dementia and AD

Even small increases in blood sugar caused by a diet high in carbohydrates can be detrimental to brain health. Recent reports in medical literature link carbohydrate calorie-rich diets to a greater risk for brain shrinkage, dementia and Alzheimer's disease, impaired cognition, and other disorders.

24 Feb 2014

Cell therapy: A powerful treatment for cancer patients

Investigators from Memorial Sloan Kettering Cancer Center have reported more encouraging news about one of the most exciting methods of cancer treatment today. The largest clinical study ever conducted to date of patients with advanced leukemia found that 88 percent achieved complete remissions after being treated with genetically modified versions of their own immune cells.

24 Feb 2014

Rapid advances and potential in 3D printing and additive manufacturing technologies

A new era of manufacturing is upon us. Recent developments in 3D printing and additive manufacturing technologies are set to usher in the next generation of industrial competitiveness.

23 Feb 2014

Researchers propose new treatment to prevent mucositis in cancer patients

Experimental work pointing to a therapy for alleviating mucositis -- a common, severe side effect of chemotherapy and irradiation of cancer patients or patients prepared for bone marrow transplantation - has been achieved by an international team of researchers from the US and Israel headed by scientists at the Hebrew University of Jerusalem.

20 Feb 2014

Researcher receives Pioneer Award for engineering herpes simplex virus gene delivery systems

Joseph C. Glorioso, III, PhD (University of Pittsburgh School of Medicine, PA) devoted much of his research career to developing herpes viruses as efficient vectors for delivering therapeutic genes into cells.

20 Feb 2014

Researchers explore possible link between metabolic defects and seizures

Researchers from the Franciscan University of Steubenville, Ohio are exploring a possible link between metabolic defects and seizures. They determined that diet could influence susceptibility to seizures, and they have identified a common diabetes drug that could be useful in treating disorders such as epilepsy.

19 Feb 2014

Researchers examine impact of diet for preventing Alzheimer's dementia

A cocktail of ingredients containing omega-3 fatty acid found in fish oil is being tested in patients with mild cognitive impairment as a means to slow the progression of Alzheimer's dementia down

19 Feb 2014

Chronic intake of marijuana protects critical immune tissue from damaging effects of HIV infection

New evidence that chronic intake of THC, the primary psychoactive ingredient in marijuana, can protect critical immune tissue in the gut from the damaging effects of HIV infection is reported in AIDS Research and Human Retroviruses, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

19 Feb 2014

Scientists find neutralizing antibodies that protects humanized mice from HIV transmission

NIH-funded scientists have shown that boosting the production of certain broadly neutralizing antibodies can protect humanized mice from both intravenous and vaginal infection with HIV. Humanized mice have immune systems genetically modified to resemble those of humans, making it possible for them to become HIV-infected.

12 Feb 2014

New approach for reducing levels of toxic protein fragments associated with Huntington's disease

An innovative therapeutic strategy for reducing the levels of toxic protein fragments associated with Huntington's disease uses a new approach called exon skipping to remove the disease-causing component of the essential protein, huntingtin.

11 Feb 2014

New study provides important understanding of what drives appetite

While the function of eating is to nourish the body, this is not what actually compels us to seek out food. Instead, it is hunger, with its stomach-growling sensations and gnawing pangs that propels us to the refrigerator - or the deli or the vending machine. Although hunger is essential for survival, abnormal hunger can lead to obesity and eating disorders, widespread problems now reaching near-epidemic proportions around the world.

9 Feb 2014

Research examines differences between male and female brain that contributes to violent behavior

Human behaviors such as violence depend on interactions in the brain between genetic and environmental factors. An individual may be more vulnerable to developing violent behaviors if they have predisposing factors and are then exposed to stress, abuse, or other triggers, especially early in life.

6 Feb 2014

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Many people with high blood pressure are familiar with ACE inhibitors, drugs that widen blood vessels by limiting activity of ACE - angiotensin-converting enzyme - a naturally occurring protein found in tissues throughout the body.

4 Feb 2014

Deficit in microglia during development can have long-lasting effects on brain wiring, behavior

In many people with autism and other neurodevelopmental disorders, different parts of the brain don't talk to each other very well. Scientists have now identified, for the first time, a way in which this decreased functional connectivity can come about.

3 Feb 2014

Ronald G. Crystal wins Pioneer Award from Human Gene Therapy

In recognition of his seminal work on adenoviral vectors, which accelerated the translation of gene therapy from the research laboratory to the clinic, Ronald G. Crystal, MD (Weill Cornell Medical College, Cornell University, New York City), has received a Pioneer Award from Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

31 Jan 2014

Genetic Engineering News and Research

Researchers discover new target for human antibodies that holds key to vaccine for dengue

Goal: Therapies for hearing loss and communications problems

Therapeutic hypothermia may not be effective in all patients who suffered heart attack, says study

Viewpoints: Finding a plan for 'tinkering with DNA'; fact-checking claims of ACA losses; pediatricians' fears of retail clinics

European Commission invests nearly $475 million in gene transfer and gene therapy projects

Study links carbohydrate calorie-rich diets to greater risk for brain shrinkage, dementia and AD

Cell therapy: A powerful treatment for cancer patients

Rapid advances and potential in 3D printing and additive manufacturing technologies

Researchers propose new treatment to prevent mucositis in cancer patients

Researcher receives Pioneer Award for engineering herpes simplex virus gene delivery systems

Researchers explore possible link between metabolic defects and seizures

Researchers examine impact of diet for preventing Alzheimer's dementia

Chronic intake of marijuana protects critical immune tissue from damaging effects of HIV infection

Scientists find neutralizing antibodies that protects humanized mice from HIV transmission

New approach for reducing levels of toxic protein fragments associated with Huntington's disease

New study provides important understanding of what drives appetite

Research examines differences between male and female brain that contributes to violent behavior

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Deficit in microglia during development can have long-lasting effects on brain wiring, behavior

Ronald G. Crystal wins Pioneer Award from Human Gene Therapy

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