Genetic Engineering News and Research

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Keystone Symposia to convene conference focusing on the science of malaria eradication

Keystone Symposia, in collaboration with MESA (Malaria Eradication Scientific Alliance), is convening its first conference in Mexico – on "The Science of Malaria Eradication" at the Fiesta Americana Hotel in Merida, Yucatan. The four-day conference begins Sunday evening, February 2, 2014 and is part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation, which has also funded travel awards for investigators from malaria-endemic countries to attend. The conference will gather experts from 37 countries.

31 Jan 2014

Dormant prostate cancer cells in bone tissue can be reawakened, say researchers

Researchers in the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute discovered in pre-clinical models that dormant prostate cancer cells found in bone tissue can be reawakened, causing metastasis to other parts of the body. Understanding this mechanism of action may allow researchers to intervene prior to disease progression.

31 Jan 2014

Scientists discover potential cure for triple negative breast cancer

Scientists have discovered a potential cure for one of the most aggressive and least treatable forms of breast cancer called "triple negative breast cancer." In laboratory experiments involving human cancer cells, scientists used a virus similar to the one that helped eradicate smallpox to coax cancer cells to produce a protein which makes them susceptible to radioactive iodine.

31 Jan 2014

Vaccine to treat precancerous cervical lesions triggers immune cell response

Preliminary results of a small clinical trial show that a vaccine used to treat women with high-grade precancerous cervical lesions triggers an immune cell response within the damaged tissue itself.

30 Jan 2014

Study: Genetic mutations in titin gene can cause skeletal muscle disease

A University of Arizona doctoral candidate has shown for the first time that genetic mutations in the titin gene can cause skeletal muscle myopathy, a disease in which muscle fibers do not function properly, resulting in muscle weakness.

29 Jan 2014

Transgenic mouse model validates mutant IDH2 protein as candidate for targeted anticancer therapies

In recent years, mutations in two metabolic enzymes, isocitrate dehydrogenase-1 and 2 (IDH1 and IDH2), have been identified in approximately 20 percent of all acute myeloid leukemias (AML). As a result, mutant IDH proteins have been proposed as attractive drug targets for this common form of adult leukemia.

29 Jan 2014

New approach for reversing hair loss uses stem cells to regenerate missing hair follicles

If the content of many a situation comedy, not to mention late-night TV advertisements, is to be believed, there's an epidemic of balding men, and an intense desire to fix their follicular deficiencies.

28 Jan 2014

Study provides possible clue to high rate of preterm labor after human fetal surgery

As a fetal surgeon at UC San Francisco, Tippi MacKenzie, MD, has long known that conducting surgery on a fetus to correct a problems such as spina bifida often results in preterm labor and premature birth.

28 Jan 2014

Study to evaluate connections between brain networks and religious thought

Building on previous evidence showing that religious belief involves cognitive activity that can be mapped to specific brain regions, a new study has found that causal, directional connections between these brain networks can be linked to differences in religious thought.

28 Jan 2014

Research: Architecture of DNA maintained by protein ANP32E

A team of scientists from the National Cancer Centre Singapore (NCCS), the Institut de G-n-tique et de Biologie Moleculaire et Cellulaire (Strassbourg France), and the Institut Albert Bonniot (Grenoble, France) have made an important finding on how genes are regulated. This study will be released in the January 30th, 2014 print issue of the journal Nature.

27 Jan 2014

Researchers detect cancer cells using olfactory senses of fruit flies

A research unit in an international cooperation project, led by the Konstanz-based neurobiologist and zoologist Professor Dr. Giovanni Galizia, has been the first to demonstrate that fruit flies are able to distinguish cancer cells from healthy cells via their olfactory sense.

25 Jan 2014

Environmental endocrine disrupters may endanger embryonic heart valves

Exposure to environmental endocrine disrupters, such as bisphenol A, which mimic estrogen, is associated with adverse health effects. Bisphenol A is commonly found in plastic bottles and plastic food containers. New research from a team including Carnegie's Daniel Gorelick and Marnie Halpern on the effects of these chemicals on zebrafish shows that embryonic heart valves could be particularly in danger. It is published by Environmental Health Perspectives.

24 Jan 2014

FDA mandates enrollment and monitoring of women in post-approval studies for medical devices

The U.S. Food and Drug Administration (FDA) mandates adequate enrollment of women in post-approval studies (PAS) of medical devices to ensure that any sex differences in device safety and effectiveness are not overlooked.

24 Jan 2014

Scientists identify critical regulator of molecule deeply involved in progression of Alzheimer's

Scientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer's disease.

24 Jan 2014

Scientists identify critical regulator of molecule involved in progression of Alzheimer’s disease

Scientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer’s disease.

23 Jan 2014

Rice University-based research develops fast biosensor for pathogens in food

An array of tiny diving boards can perform the Olympian feat of identifying many strains of salmonella at once.

23 Jan 2014

Vitamin D deficiency may lead to stiffening of blood vessels

UV-B radiation in sunlight is the most important factor for the production of vitamin D, and that is why many people suffer from low levels of vitamin D during the winter months.

20 Jan 2014

Researchers discover fundamental biology of calcium waves in relation to heart arrhythmias

Researchers have discovered the fundamental biology of calcium waves in relation to heart arrhythmias. The findings published this month in the January 19 edition of Nature Medicine outlines the discovery of this fundamental physiological process that researchers hope will one day help design molecularly tailored medications that correct the pathophysiology.

20 Jan 2014

New gene therapy restores some sight in people born with inherited form of blindness

A new gene therapy has restored some sight in people born with an inherited, progressive form of blindness. The technique replaces a defective gene in the eye with a normal working copy of the gene using a single injection.

16 Jan 2014

Study: HIV-specific poison kills persisting HIV-infected cells during antiretroviral therapy

A team including University of North Carolina and NIH scientists has demonstrated in a mouse model that an HIV-specific poison can kill cells in which the virus is actively reproducing despite antiretroviral therapy.

10 Jan 2014

Genetic Engineering News and Research

Keystone Symposia to convene conference focusing on the science of malaria eradication

Dormant prostate cancer cells in bone tissue can be reawakened, say researchers

Scientists discover potential cure for triple negative breast cancer

Vaccine to treat precancerous cervical lesions triggers immune cell response

Study: Genetic mutations in titin gene can cause skeletal muscle disease

Transgenic mouse model validates mutant IDH2 protein as candidate for targeted anticancer therapies

New approach for reversing hair loss uses stem cells to regenerate missing hair follicles

Study provides possible clue to high rate of preterm labor after human fetal surgery

Study to evaluate connections between brain networks and religious thought

Research: Architecture of DNA maintained by protein ANP32E

Researchers detect cancer cells using olfactory senses of fruit flies

Environmental endocrine disrupters may endanger embryonic heart valves

FDA mandates enrollment and monitoring of women in post-approval studies for medical devices

Scientists identify critical regulator of molecule deeply involved in progression of Alzheimer's

Scientists identify critical regulator of molecule involved in progression of Alzheimer’s disease

Rice University-based research develops fast biosensor for pathogens in food

Vitamin D deficiency may lead to stiffening of blood vessels

Researchers discover fundamental biology of calcium waves in relation to heart arrhythmias

New gene therapy restores some sight in people born with inherited form of blindness

Study: HIV-specific poison kills persisting HIV-infected cells during antiretroviral therapy

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