Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

New test detects Zika antibodies with high specificity

A test that detects antibodies against Zika virus in samples of blood serum with high specificity - and hence a low risk of cross-reaction with related microorganisms such as dengue virus - is set to come on to the Brazilian market before 2018 is out.

28 Mar 2018

Biophysical mechanism involving spaghetti-like proteins helps cells avoid 'data breaches'

Cells can avoid "data breaches" when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert Einstein College of Medicine have shown.

28 Mar 2018

Simple bedside test may help doctors diagnose certain degenerative brain diseases

A simple bedside test that matches a change in heart rate with a drop in blood pressure after a patient stands may help doctors diagnose certain degenerative brain diseases.

28 Mar 2018

Study provides insights into how male germ cells avoid genome instability

A group of researchers at Osaka University reported the function of GTSF1 in male germ cells. The study, which can be read in EMBO Reports, shows that GTSF1 is an essential factor for secondary piRNA biogenesis by regulating piRNA-mediated cleavage of target RNA.

28 Mar 2018

Researchers reveal role of extracellular protein in tumor growth and sustenance

Researchers at Okayama University describe in the journal Scientific Reports the role of an extracellular protein, versican, in regulating tumor growth and providing a newly formed network of blood vessels to further nourish the tumor.

28 Mar 2018

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

EPFL biologists and geneticists have uncovered how the circadian clock orchestrates the 24-hour cycle of gene expression by regulating the structure of chromatin, the tightly wound DNA-protein complex of the cell. The work is published in Genes & Development.

28 Mar 2018

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Wistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for the treatment of diseases such as leukemia, as a new therapeutic option for ovarian cancer with mutations in the ARID1A gene.

27 Mar 2018

Previously unknown feature of human anatomy identified

Researchers have identified a previously unknown feature of human anatomy with implications for the function of all organs, most tissues and the mechanisms of most major diseases.

27 Mar 2018

Screening strategies could reduce multiple myeloma prevalence, mortality

Multiple myeloma is a rare incurable disease that is diagnosed in more than 30,000 people each year in the United States.

27 Mar 2018

Johns Hopkins researchers make great strides in understanding biology behind pulmonary hypertension

Working with cells that line the innermost layer of the blood vessels, Johns Hopkins investigators say they have made a leap forward in understanding the underlying biology behind pulmonary hypertension, a dangerous type of high blood pressure in lungs that ultimately leads to right heart failure and death.

27 Mar 2018

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Each day, normal human cell tissues express a protein known as p53 that wages war against potential malignancies. However, between 30 and 40 percent of human breast cancers express a defective (mutant) form of p53 that helps cancer cells proliferate and grow.

27 Mar 2018

MSU scientists test promising drug to prevent cancer in high-risk patients

Michigan State University scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.

27 Mar 2018

Antibody sweeps away Alzheimer's plaques in mice

Years before people start showing characteristic symptoms of Alzheimer's disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a way to prevent or treat the disease.

27 Mar 2018

USC researchers launch global project that aims to curb worldwide rise of diabetes

USC researchers have launched a massive scientific effort to construct a detailed, virtual 3-D model of the pancreatic beta cell and its components -- a global project that aims to one day curb the worldwide rise of diabetes.

26 Mar 2018

Scientists discover new family of promising silver-based anti-cancer drugs

A new family of very promising silver-based anti-cancer drugs has been discovered by researchers in South Africa. The most promising silver thiocyanate phosphine complex among these, called UJ3 for short, has been successfully tested in rats and in human cancer cells in the laboratory.

26 Mar 2018

Daily regimen of ibuprofen can ward off Alzheimer's disease, say neuroscientists

A Vancouver-based research team led by Canada's most cited neuroscientist, Dr. Patrick McGeer, has successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent the onset of Alzheimer's disease.

26 Mar 2018

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Drug resistance is a major obstacle to effective treatment for patients with cancer and leukemia. Epigenetic modifying drugs have been proven effective for some patients with hematologic malignancies, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).

23 Mar 2018

Protein News and Research

Further Reading

New test detects Zika antibodies with high specificity

Biophysical mechanism involving spaghetti-like proteins helps cells avoid 'data breaches'

Simple bedside test may help doctors diagnose certain degenerative brain diseases

Study provides insights into how male germ cells avoid genome instability

Researchers reveal role of extracellular protein in tumor growth and sustenance

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Previously unknown feature of human anatomy identified

Screening strategies could reduce multiple myeloma prevalence, mortality

Johns Hopkins researchers make great strides in understanding biology behind pulmonary hypertension

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

MSU scientists test promising drug to prevent cancer in high-risk patients

Antibody sweeps away Alzheimer's plaques in mice

USC researchers launch global project that aims to curb worldwide rise of diabetes

Scientists discover new family of promising silver-based anti-cancer drugs

Daily regimen of ibuprofen can ward off Alzheimer's disease, say neuroscientists

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Researchers characterize S. aureus gene involved in virulence and antibiotic resistance

Genetic mutation that may protect people from malaria found to be more common

Mutations found in bassoon gene may help explain cause of rare brain disorder

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