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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Researchers unravel how gingival mesenchymal stem cells accelerate wound healing

Ever notice how a cut inside the mouth heals much faster than a cut to the skin? Gum tissue repairs itself roughly twice as fast as skin and with reduced scar formation. One reason might be because of the characteristics of gingival mesenchymal stem cells, or GMSCs, which can give rise to a variety of cell types.

15 Mar 2018

University of Akron professor receives NSF grant for research that supports anti-cancer therapeutics

Dr. Adam W. Smith, assistant professor in the Department of Chemistry, has won a CAREER award from the National Science Foundation. The title of the award is "Lipid Regulation of Receptor Tyrosine Kinases" and provides $650,000 of funding for research.

15 Mar 2018

Researcher working to develop improved endoscopic probe for colonoscopies

Tim Muldoon, assistant professor of biomedical engineering, has received a $500,000 Faculty Early Career Development Program award from the National Science Foundation to continue his work on an endoscopic probe that can be used in colonoscopies.

14 Mar 2018

Scientists explore how to protect obese, premenopausal women from cardiovascular risk

Obese, premenopausal women can lose the innate protection from cardiovascular disease that their youth and estrogen are believed to afford, and scientists want to know how.

14 Mar 2018

Researchers achieve 80% reduction in liver metastasis by restricting growth of blood vessels

The International Journal of Cancer has just published the results of an experimental therapy tested on mice. The research, led by the Signaling Lab research group of the UPV/EHU's Faculty of Medicine and Pharmacy and the Department of Pharmacology, Pharmacy and Pharmaceutical Technology of the University of Santiago de Compostela, achieved an 80% reduction in liver metastasis brought about by colon cancer.

14 Mar 2018

Researchers identify novel gene involved in familial breast cancer

An international research consortium led by Dr Jordi Surrallés, director of the Genetics Service at the Hospital de Sant Pau and professor of Genetics at the UAB, and by Dr Miquel Àngel Pujana, director of the ProCURE Research Programme of the Catalan Institute of Oncology, has identified a novel gene involved in this type of cancer, known as EDC4.

14 Mar 2018

Tumor's 'microenvironment' plays key role in altering therapeutic response of breast cancer

Cancer is typically thought of as a tumor that needs to be removed or an area that needs to be treated with radiation or chemotherapy. As a physicist and cancer researcher, Joe Gray, Ph.D., thinks differently.

14 Mar 2018

NIH researchers explore genetic clocks to understand role of aging in neurodegeneration

To understand the link between aging and neurodegenerative disorders such as Alzheimer's disease, NIH scientists compared the genetic clocks that tick during the lives of normal and mutant flies.

14 Mar 2018

Study highlights divergent molecular mechanisms contributing to depression in men and women

Men and women with major depressive disorder have opposite changes in the expression of the same genes, according to a new postmortem brain study by researchers at the University of Pittsburgh and Centre for Addiction and Mental Health, Toronto, Canada.

14 Mar 2018

New guidelines intend to provide template for optimal, most up-to-date DMD care

Diagnostic and treatment advances are helping patients with Duchenne muscular dystrophy - one of nine major types of muscular dystrophy that affects males - live into their 30s and beyond, raising challenges in such areas as education, vocation, levels of independence, personal relationships, emotional health, and intimacy.

13 Mar 2018

Study: Soy-fed infants have differences in reproductive system tissues

Infants who consumed soy-based formula as newborns had differences in some reproductive-system cells and tissues, compared to those who used cow-milk formula or were breastfed, according to a new study.

13 Mar 2018

Extracellular vesicles may serve as drug delivery vehicles for cancer treatment

Creating enough nanovesicles to inexpensively serve as a drug delivery system may be as simple as putting the cells through a sieve, according to an international team of researchers who used mouse autologous -- their own -- immune cells to create large amounts of fillable nanovesicles to deliver drugs to tumors in mice.

13 Mar 2018

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

NIH-funded researchers at Stanford University used the gene editing tool CRISPR-Cas9 to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis and frontotemporal dementia caused by mutations in a gene called C9orf72.

13 Mar 2018

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Tracking the growth and migration of cells under hypoxic conditions in vitro can be challenging because measurements must be made in a manner that does not perturb the atmospheric composition of the closed system.

13 Mar 2018

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

A team of Italian scientists reported this week that blocking the interaction between urokinase receptor (uPAR) and formyl peptide receptor type 1 (FPR1) suppresses the ability of melanoma cells to migrate, invade through an extracellular matrix, and to burrow through a layer of endothelial cells.

13 Mar 2018

Study sheds new light on viral replication

Viruses are intracellular parasites that cause disease by infecting the cells in the body and, in a study published today in Nature Microbiology, researchers at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine showed how a common virus hijacks a host cell's protein to help assemble new viruses before they are released.

13 Mar 2018

Study identifies two new biomarkers for common form of childhood cancer

Two new biomarkers for a type of cancer in children called neuroblastoma have been identified in a study published in the journal Cancer Cell. The findings are expected to have immediate significance for disease prognosis, and eventually also for treatment.

13 Mar 2018

Protein News and Research

Further Reading

Researchers unravel how gingival mesenchymal stem cells accelerate wound healing

University of Akron professor receives NSF grant for research that supports anti-cancer therapeutics

Researcher working to develop improved endoscopic probe for colonoscopies

Scientists explore how to protect obese, premenopausal women from cardiovascular risk

Researchers achieve 80% reduction in liver metastasis by restricting growth of blood vessels

Researchers identify novel gene involved in familial breast cancer

Tumor's 'microenvironment' plays key role in altering therapeutic response of breast cancer

NIH researchers explore genetic clocks to understand role of aging in neurodegeneration

Study highlights divergent molecular mechanisms contributing to depression in men and women

New guidelines intend to provide template for optimal, most up-to-date DMD care

Study: Soy-fed infants have differences in reproductive system tissues

Extracellular vesicles may serve as drug delivery vehicles for cancer treatment

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

Study sheds new light on viral replication

Study identifies two new biomarkers for common form of childhood cancer

International research consortium identifies 22 new genetic risk factors for stroke

Southern Research scientists target mutated protein to combat prostate cancer

Protein pathways linked to heart disease, diabetic complications identified in patients with diabetes

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