Mastectomy News and Research

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Mastectomy is surgery to remove the breast (or as much of the breast tissue as possible).

Transgender health care targeted in crusade to undo ACA

Solorah Singleton has been waiting years for breast augmentation. She doesn't want to jinx it now, but the Philadelphia resident thinks it's finally within reach.

13 Jul 2017

Adding a second HER2-targeted treatment may improve outcomes for some women with breast cancer

A phase III clinical trial of 4,805 women with HER2-positive breast cancer suggests adding a second HER2 targeted medicine, pertuzumab (Perjeta), to standard of care trastuzumab (Herceptin) after surgery may help, although the benefit is modest.

6 Jun 2017

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

A new study has shown that AstraZeneca's Lynparza (olaparib) can significantly slow the progress of breast cancer that is caused partially due to mutations of the culprit gene called BRCA. BRCA gene mutations are responsible for around 3% of all breast cancers. These cases of the disease that have a basis in the gene are notoriously difficult to treat and women who are tested positive for this gene may even opt for removal of their breasts before even the cancer strikes. Noted actress Angelina Jolie went for a similar prophylactic mastectomy.

5 Jun 2017

Open-access BRCA testing for inherited breast cancer enables identification of missed carriers

Ashkenazi Jewish women are known to have a predisposition to the inherited breast cancers BRCA1 and BRCA2, but currently genetic testing in this group is limited to women affected by breast and ovarian cancers and those who are unaffected but have a family history of the disease.

27 May 2017

New imaging technology could reduce the need for additional cancer surgeries

Engineers at the Optical Imaging Laboratory led by Caltech's Lihong Wang have developed an imaging technology that could help surgeons removing breast cancer lumps confirm that they have cut out the entire tumor--reducing the need for additional surgeries.

18 May 2017

Study finds shorter course of radiation therapy given after mastectomy to be safe and effective

A shorter course of radiation therapy given to breast cancer patients following mastectomy is safe and effective and cuts treatment time in half. That is according to data from a phase II clinical trial conducted by Rutgers Cancer Institute of New Jersey investigators and other colleagues who examined a hypofractionated regimen given over three weeks versus the traditional six week course of treatment.

2 May 2017

Study finds high degree of discordance between Myriad Genetics and public database in BRCA1 and BRCA2 variant classifications

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced that new data comparing BRCA1 and BRCA2 variant classifications between Myriad Genetics and a commonly used public genetic database was published in the journal The Oncologist.

21 Apr 2017

Different therapies for early-stage breast cancer show wide variations in cost-effectiveness

A new study published today in the Journal of the National Cancer Institute indicates that different therapies for early-stage breast cancer have very different relative values.

10 Apr 2017

Study examines interaction between patients' desire for CPM and surgeons' duty to minimize harm

More women with breast cancer are electing to have both breasts removed, even when cancer affects only one breast. The procedure, called contralateral prophylactic mastectomy (CPM), is a more complex surgery that has not been shown to improve survival.

6 Apr 2017

Study: Major databases provide varying estimates of racial gaps in IBR after mastectomy

Three major national databases include varying estimates of racial gaps in the use of immediate breast reconstruction (IBR) after mastectomy for breast cancer, reports a study in the March issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

30 Mar 2017

Phase-contrast X-ray imaging could identify tumors earlier

Phase-contrast X-ray imaging differs from conventional X-rays because it uses a different physical principle.

29 Mar 2017

Study explores links between genetic susceptibility and heterogeneous phenotypes of lymphedema

Each year, about 1.38 million women worldwide are diagnosed with breast cancer. Advances in diagnosis and treatment have facilitated a 90-percent, five-year survival rate, among those treated.

9 Feb 2017

Breast reconstruction after mastectomy offered less often to older women, study finds

A national study from England indicates that older women are often not offered immediate breast reconstruction following a mastectomy, even though guidelines state that surgeons should discuss reconstruction with all suitable patients and that it should be available at the initial surgical operation.

8 Feb 2017

Study finds under and misuse of adjuvant endocrine therapy for breast cancer patients

A nationwide cancer registry of almost one million patients treated for hormone-sensitive breast cancer shows that one out of six women who should have received post-surgical treatment known as adjuvant endocrine therapy (AET) did not get this recommended component of care.

3 Feb 2017

Mayo Clinic to test vaccine for providing lifelong immunity against precancerous breast lesions

Only about 35 percent of precancerous breast lesions morph into cancer if untreated, but physicians cannot identify which lesions are potentially dangerous.

2 Feb 2017

Breast conserving therapy better than mastectomy in early-stage breast cancer patients

Breast conserving therapy (BCT, breast conserving surgery combined with radiation therapy) is superior to mastectomy in certain types of breast cancer patients, according to results from the largest study to date, to be presented to the European Cancer Congress 2017 today.

30 Jan 2017

Study: Half of women treated for early stage breast cancer report severe side effects

Nearly half of women treated for early stage breast cancer reported at least one side effect from their treatment that was severe or very severe, a new study finds.

24 Jan 2017

Oncotype DX test can help guide treatment decisions and enable personalized care before breast cancer surgery

New data presented at the 2016 San Antonio Breast Cancer Symposium (SABCS) demonstrate that analyzing tumor biology with the Oncotype DX test can identify patients unlikely to benefit from chemotherapy prior to breast cancer surgery (neoadjuvant setting) and guide treatment decisions without compromising outcomes.

22 Dec 2016

Increase in double mastectomy is “striking,” says study

Almost half of patients with early stage breast cancer considered double mastectomy and one in six went ahead, including many who were only at a low risk of developing another breast cancer, according to a new study.

22 Dec 2016

Survey finds substantial use of CPM procedure among women with unilateral breast cancer

In a survey of women who underwent treatment for early-stage breast cancer in one breast, contralateral prophylactic mastectomy use was substantial among patients without clinical indications but was low when patients reported that their surgeon recommended against it, according to a study published online by JAMA Surgery.

22 Dec 2016

Mastectomy News and Research

Further Reading

Transgender health care targeted in crusade to undo ACA

Adding a second HER2-targeted treatment may improve outcomes for some women with breast cancer

Positive results for AstraZeneca’s PARP inhibitor Lynparza in advanced breast cancer

Open-access BRCA testing for inherited breast cancer enables identification of missed carriers

New imaging technology could reduce the need for additional cancer surgeries

Study finds shorter course of radiation therapy given after mastectomy to be safe and effective

Study finds high degree of discordance between Myriad Genetics and public database in BRCA1 and BRCA2 variant classifications

Different therapies for early-stage breast cancer show wide variations in cost-effectiveness

Study examines interaction between patients' desire for CPM and surgeons' duty to minimize harm

Study: Major databases provide varying estimates of racial gaps in IBR after mastectomy

Phase-contrast X-ray imaging could identify tumors earlier

Study explores links between genetic susceptibility and heterogeneous phenotypes of lymphedema

Breast reconstruction after mastectomy offered less often to older women, study finds

Study finds under and misuse of adjuvant endocrine therapy for breast cancer patients

Mayo Clinic to test vaccine for providing lifelong immunity against precancerous breast lesions

Breast conserving therapy better than mastectomy in early-stage breast cancer patients

Study: Half of women treated for early stage breast cancer report severe side effects

Oncotype DX test can help guide treatment decisions and enable personalized care before breast cancer surgery

Increase in double mastectomy is “striking,” says study

Survey finds substantial use of CPM procedure among women with unilateral breast cancer

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