Rheumatism News and Research

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Rheumatism is a group of disorders marked by inflammation or pain in the connective tissue structures of the body. These structures include bone, cartilage, and fat.

Two studies shed light on joint replacement outcomes in rheumatoid arthritis patients

Two new studies by researchers at Hospital for Special Surgery have shed light on joint replacement outcomes in patients with rheumatoid arthritis. One study overturns the common belief that RA patients have worse outcomes after a total knee replacement than patients who undergo the operation for osteoarthritis. The other study demonstrates that RA patients who undergo a total hip replacement were as likely to have significant improvements in function and pain as patients with osteoarthritis, even though they did not do as well.

12 Jun 2013

Only one-fifth of RA patients had overall adherence rate to prescribed oral medications, study finds

A new study conducted in an ethnically diverse and predominantly low income population found that only one-fifth of rheumatoid arthritis patients had an overall adherence rate to prescribed oral medications at 80% or greater.

1 Jun 2013

Research reveals vitamin C does not reduce urate levels in gout patients

Despite previous studies touting its benefit in moderating gout risk, new research reveals that vitamin C, also known ascorbic acid, does not reduce uric acid (urate) levels to a clinically significant degree in patients with established gout. Vitamin C supplementation, alone or in combination with allopurinol, appears to have a weak effect on lowering uric acid levels in gout patients according to the results published in the American College of Rheumatology (ACR) journal, Arthritis & Rheumatism.

17 May 2013

Research: Mobility shoes improve knee loading for osteoarthritis patients

New research suggests that patients with knee osteoarthritis (OA) who wear flat, flexible footwear (mobility shoes) had significant reduction in knee loading-the force placed upon the joint during daily activities.

10 Apr 2013

Only 50% people with arthritis report significant improvement after hip or knee replacement

Only half of people with arthritis who had a hip or knee replacement reported a significant improvement in pain and mobility after surgery, according to a new study led by Women's College Hospital and the Institute for Clinical and Evaluative Sciences (ICES).

5 Apr 2013

Japan's MHLW approves XELJANZ for treatment of adults with rheumatoid arthritis

Pfizer Inc. announced today that the Japanese Ministry of Health, Labor and Welfare has approved XELJANZ (tofacitinib citrate) for the treatment of adults with rheumatoid arthritis who have had an inadequate response to existing therapies.

25 Mar 2013

Double-jointed teens at risk for later pain

Adolescents who have hypermobile joints or are “double jointed” are more likely to develop moderate to severe joint pain in later years, show study findings.

28 Feb 2013

Hypermobile children at greater risk for joint pain as they get older

A prospective study by U.K. researchers found that adolescents who are double-jointed—medically termed joint hypermobility—are at greater risk for developing musculoskeletal pain as they get older, particularly in the shoulders, knees, ankles and feet. Findings published in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), indicate that children with joint hypermobility are approximately twice as likely to develop pain at these joints.

28 Feb 2013

Adolescents with joint hypermobility more likely to develop musculoskeletal pain

A prospective study by U.K. researchers found that adolescents who are double-jointed-medically termed joint hypermobility-are at greater risk for developing musculoskeletal pain as they get older, particularly in the shoulders, knees, ankles and feet.

28 Feb 2013

Fibromyalgia prevalence is 2.1% of the general population in Germany

Researchers have determined that fibromyalgia prevalence is 2.1% of the general population in Germany. Results appearing in Arthritis Care & Research, a journal published by Wiley on behalf of the American College of Rheumatology (ACR), suggest that fibromyalgia is a spectrum disorder rather than a categorical illness. Additionally, a number of fibromyalgia cases in the general population satisfy proposed criteria for physical symptom disorder—the presence of one or more physical symptoms that impair function, which cannot be explained by another clinical or psychiatric illness.

19 Feb 2013

Research reveals how quickly the Achilles tendon can regenerate

The Achilles heel of the body - getting over damage to tendons can be a long and painful process. By combining the nuclear tests of the 1950s with tissue samples and modern technology, a research collaboration between the Aarhus University and University of Copenhagen now reveals why the healing process is so slow.

18 Feb 2013

Combination of Methotrexat and Tofacitinib shows promise against rheumatoid arthritis

Together with colleagues from the international rheumatic diseases research community, scientists of the Charité - Universitätsmedizin Berlin have presented a new therapy approach for the treatment of rheumatoid arthritis (RA), a chronic form of joint inflammation.

14 Feb 2013

Tofacitinib fights rheumatoid arthritis progression

Tofacitinib treats symptoms and prevents structural damage in patients with rheumatoid arthritis who do not respond well to methotrexate, indicate phase III trial findings.

29 Jan 2013

Tofacitinib improves disease activity and inhibits progression of joint damage in RA patients

A Phase 3 clinical trial demonstrates that tofacitinib improves disease activity and inhibits progression of joint damage in rheumatoid arthritis (RA) patients who did not respond to methotrexate (MTX).

24 Jan 2013

DFG now extends funding for research on immunological therapy at Charité

The DFG (Deutsche Forschungsgemeinschaft) has now extended the funding of a research association which is located at the Charité - Universitätsmedizin Berlin. The Collaborative Research Centre (SFB) will receive funding in excess of ten million Euros over the next four years.

23 Jan 2013

TNF inhibitor efficacy may depend on brain activity

How well a patient responds to tumor necrosis factor inhibitor therapy may depend on brain activity reflecting the individual’s perception of their rheumatoid arthritis, scientists believe.

24 Dec 2012

Arthritis, rheumatism and total joint arthroplasty: an interview with Dr Ravi and Dr Hawker

Arthritis translates to “joint inflammation.” The most common form of arthritis is osteoarthritis (OA), which affects 12-15% of North Americans over the age of 60, and will increase in prevalence as our population ages.

19 Dec 2012

Patients with RA more likely to have dislocation following hip replacement surgery

In the first systemic review of evidence assessing complications following total joint arthroplasty, patients with rheumatoid arthritis (RA) were found to have an increased risk for hip dislocation after hip replacement surgery compared to those with osteoarthritis (OA). Study findings published online in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), also indicate that RA patients have a higher infection risk following total knee replacement than patients with OA.

28 Nov 2012

Rituximab may help patients with aPL-related clinical problems

Rituximab, a drug used to treat cancer and arthritis, may help patients with antiphospholipid antibodies (aPLs) who suffer from aPL-related clinical problems that do not respond to anticoagulation, such as cardiac disease and kidney disease, according to a new study by rheumatology researchers at Hospital for Special Surgery. The study appears online ahead of print, in the journal Arthritis and Rheumatism.

21 Nov 2012

Gout diagnosis possible for rheumatoid arthritis patients

Rheumatoid arthritis patients can develop gout, say researchers who believe changes in treatment and obesity may explain why the comorbidity is now occurring.

12 Nov 2012

Rheumatism News and Research

Further Reading

Two studies shed light on joint replacement outcomes in rheumatoid arthritis patients

Only one-fifth of RA patients had overall adherence rate to prescribed oral medications, study finds

Research reveals vitamin C does not reduce urate levels in gout patients

Research: Mobility shoes improve knee loading for osteoarthritis patients

Only 50% people with arthritis report significant improvement after hip or knee replacement

Japan's MHLW approves XELJANZ for treatment of adults with rheumatoid arthritis

Double-jointed teens at risk for later pain

Hypermobile children at greater risk for joint pain as they get older

Adolescents with joint hypermobility more likely to develop musculoskeletal pain

Fibromyalgia prevalence is 2.1% of the general population in Germany

Research reveals how quickly the Achilles tendon can regenerate

Combination of Methotrexat and Tofacitinib shows promise against rheumatoid arthritis

Tofacitinib fights rheumatoid arthritis progression

Tofacitinib improves disease activity and inhibits progression of joint damage in RA patients

DFG now extends funding for research on immunological therapy at Charité

TNF inhibitor efficacy may depend on brain activity

Arthritis, rheumatism and total joint arthroplasty: an interview with Dr Ravi and Dr Hawker

Patients with RA more likely to have dislocation following hip replacement surgery

Rituximab may help patients with aPL-related clinical problems

Gout diagnosis possible for rheumatoid arthritis patients

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

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