Biochemistry News and Research

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Researchers find metabolite shuttle between cells in the liver that may combat tissue fibrosis

University of Minnesota Medical School researchers have made a discovery which could lead to a new way of thinking about how disease pathogenesis in the liver is regulated, which is important for understanding the condition nonalcoholic fatty liver disease, which is incredibly common and growing.

16 Nov 2018

Cranberry consumption modifies impact of animal-based diet on gut health

In a recently published feeding trial in The Journal of Nutritional Biochemistry, scientists investigated the potential protective effect of cranberries on the gut microbiome with an animal-based diet.

13 Nov 2018

Study provides new clues to origin and development of multiple sclerosis

Mapping of a certain group of cells, known as oligodendrocytes, in the central nervous system of a mouse model of multiple sclerosis, shows that they might have a significant role in the development of the disease.

12 Nov 2018

Researchers discover possible path forward in preventing cancers tied to two viruses

Researchers from the University of Minnesota, the Howard Hughes Medical Institute, and the University of Toronto have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis--more commonly known as mono or the "kissing disease"--that infects millions of people around the globe each year.

12 Nov 2018

Scientists develop new method to produce irradiated nanomaterials for medical applications

Under the leadership of Petr Cígler from the Institute of Organic Chemistry and Biochemistry and Martin Hrubý from the Institute of Macromolecular Chemistry, both of which are part of the Czech Academy of Sciences, a team of researchers has developed a revolutionary method for the easy and inexpensive production of irradiated nanodiamonds and other nanomaterials suitable for use in highly sensitive diagnostics of diseases, including various types of cancer.

12 Nov 2018

UCI researchers accelerate and simplify directed evolution bioengineering technique

In a process known as directed evolution, scientists reengineer biomolecules to find ones that perform beneficial new functions. The field is revolutionizing drug development, chemical engineering and other applications, but to realize its promise involves painstaking and time-consuming laboratory work.

9 Nov 2018

Small molecules designed to inhibit activity of enzymes in infectious diseases

A multidisciplinary study by the Computer Biochemistry Research Group of the Universitat Jaume I from Castellón, Spain, in collaboration with groups from universities from Canada and the United Kingdom, have designed small molecules that are able to bond with and inhibit the activity of enzymes in infectious diseases.

8 Nov 2018

New research to understand fundamental role of ubiquitin in cell death or survival

An effective regulation of programmed cell death is crucial for the correct development of embryos, a working innate immune system, and the prevention of cancer. How cells control the switch between cell survival and death, and which signaling pathways are involved, remain unclear.

8 Nov 2018

WPI professor explores how lipids in our bodies and cell membranes affect aging, long-term health

A professor at Worcester Polytechnic Institute is exploring aging on the molecular level, examining how the lipids found in our bodies, particularly those in our cell membranes, change as we age, and how those changes may affect bone and muscle strength, brain health, and our propensity for age-related diseases, including Alzheimer's disease.

7 Nov 2018

Molecular virologist uses basic science to fight influenza

Molecular virologist Chad Petit, Ph.D., uses basic science to fight influenza -- through experiments at the atomic level.

3 Nov 2018

Researchers for first time view serotonin activating its receptor using high-powered microscopes

Serotonin receptors are common drug targets in the treatment of pain, gastrointestinal dysfunctions, and mood disorders yet little is known about their three-dimensional structure.

2 Nov 2018

Research reveals how Mycoplasma pathogens sneak past our line of defense

New research reveals that Mycoplasma pathogens make DNA in a unique way that may protect them from our immune response. The result could provide new avenues to combat the pathogens that utilize this strategy.

1 Nov 2018

Toxic protein assemblies found to play beneficial role in muscle generation

Toxic protein assemblies, or "amyloids," long considered to be key drivers in many neuromuscular diseases, also play a beneficial role in the development of healthy muscle tissue, University of Colorado Boulder researchers have found.

1 Nov 2018

New insight on quality control in the cellular immune system

Robert Tampé, Director of the Institute of Biochemistry at Goethe University, has received € 1.5 million from the German Research Foundation for a Reinhart Koselleck project.

31 Oct 2018

Study: Infants born at home have more diverse bacteria in their guts, feces

Infants born at home have more diverse bacteria in their guts and feces, which may affect their developing immunity and metabolism, according to a study in Scientific Reports.

31 Oct 2018

Genetic defect linked to ALS causes sugar-starved cells to overproduce lipids

A genetic defect tied to a variety of neurodegenerative diseases and mental illnesses changes how cells starved of sugar metabolize fatty compounds known as lipids, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health shows.

31 Oct 2018

Cryo-electron microscopy helps study proteins responsible for amyloid-based diseases

The century old mission to understand how the proteins responsible for amyloid-based diseases such as Alzheimer's, Huntingdon's and Parkinson's work has taken major steps forward in the last 12 months, thanks to a revolution in a powerful microscopy technique used by scientists.

30 Oct 2018

Researchers deconstruct royal jelly that determines honeybee hierarchy

Katharina Paschinger's father, a conservation chemist in Vienna, was a devoted beekeeper. Paschinger remembers fondly that he would bring royal jelly, an important food for bee larvae, as a gift on visits to her maternal grandmother.

30 Oct 2018

Insilico to present latest research on biomarkers at Investing in the Age of Longevity Conference

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest advances in human aging biomarker development at the Investing in the Age of Longevity Conference in London, 1 of November.

30 Oct 2018

New method allows detection of direct biomolecule interactions

Proteins are the building blocks of the cell. They do most of the work and are essential for the structure, function and dynamic regulation of the cell and body's tissues and organs.

26 Oct 2018

Biochemistry News and Research

Researchers find metabolite shuttle between cells in the liver that may combat tissue fibrosis

Cranberry consumption modifies impact of animal-based diet on gut health

Study provides new clues to origin and development of multiple sclerosis

Researchers discover possible path forward in preventing cancers tied to two viruses

Scientists develop new method to produce irradiated nanomaterials for medical applications

UCI researchers accelerate and simplify directed evolution bioengineering technique

Small molecules designed to inhibit activity of enzymes in infectious diseases

New research to understand fundamental role of ubiquitin in cell death or survival

WPI professor explores how lipids in our bodies and cell membranes affect aging, long-term health

Molecular virologist uses basic science to fight influenza

Researchers for first time view serotonin activating its receptor using high-powered microscopes

Research reveals how Mycoplasma pathogens sneak past our line of defense

Toxic protein assemblies found to play beneficial role in muscle generation

New insight on quality control in the cellular immune system

Study: Infants born at home have more diverse bacteria in their guts, feces

Genetic defect linked to ALS causes sugar-starved cells to overproduce lipids

Cryo-electron microscopy helps study proteins responsible for amyloid-based diseases

Researchers deconstruct royal jelly that determines honeybee hierarchy

Insilico to present latest research on biomarkers at Investing in the Age of Longevity Conference

New method allows detection of direct biomolecule interactions

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