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New NIST Standard Reference Material helps ensure accurate measurements of HER2 breast cancer gene

A new measurement standard developed by the National Institute of Standards of Technology has been used successfully by the Frederick National Laboratory for Cancer Research to check the performance of next-generation DNA-sequencing technologies for evaluating gene variations associated with an increased risk of breast cancer.

18 Aug 2016

New research article reveals global patterns of genetic variation

Published in today's edition of Nature, the research led by Dr Monkol Lek of the University of Sydney and Dr Daniel MacArthur of The Broad Institute of MIT and Harvard Universities reveals patterns of genetic variation worldwide by sequencing the exomes of 60,706 individuals with diverse geographic ancestries, including European, African, South Asian, East Asian and Latino populations.

18 Aug 2016

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely.

18 Aug 2016

New clinical trial to examine safety of checkpoint inhibitor in pediatric cancer patients

In an innovative, first-in-pediatrics study, available only at Children's Hospital Los Angeles, researchers will be enrolling children between 1 and 18 years of age who have certain types of relapsed or treatment-resistant cancer.

18 Aug 2016

New book from Cold Spring Harbor examines major antibiotics and mechanisms of resistance

One of the greatest medical accomplishments of the past century was the introduction of antibiotics into the clinic.

18 Aug 2016

Salk researchers identify new mechanism for Alzheimer's risk gene

For decades, scientists have known that people with two copies of a gene called apolipoprotein E4 (ApoE4) are much more likely to have Alzheimer's disease at age 65 than the rest of the population.

18 Aug 2016

Novel material heals diabetic wounds faster than standard bandage

At some point in their lives, 15 percent of people with diabetes will develop a painful and hard-to-treat foot ulcer.

18 Aug 2016

Research shines more light on role of proteins in maintaining synaptic transmission

Synapses are the power junctions that allow living creatures to function. Popularly associated with learning and memory, they play a more fundamental role in our existence by regulating everything from breathing, sleeping and waking and other bodily functions.

17 Aug 2016

Researchers find potential way to reduce effects of TBI with neuron-targeting nanoparticle

A fall down the stairs, a car crash, a sports injury or an explosive blast can all cause traumatic brain injury (TBI).

17 Aug 2016

Scientists working on new approach to produce fruit protein far sweeter than sugar

High-fructose corn syrup and sugar are on the outs with calorie-wary consumers. As a result, low- and no-calorie alternatives have become popular, and soon, there could be another option that tastes more sugar-like than other substitutes.

17 Aug 2016

New test holds potential to revolutionise diagnosis of childhood leukaemia

Researchers at The University of Manchester have unlocked the potential of a new test which could revolutionise the way doctors diagnose and monitor a common childhood leukaemia.

17 Aug 2016

Molecular alarm clock awakens ovules from resting period

At the start of reproductive life an ovary contains, on average, several thousands of immature ovules in a resting state that can last for several decades.

17 Aug 2016

TSRI scientists tackle decades-old challenge by re-creating primordial RNA world

Scientists at The Scripps Research Institute (TSRI) have taken a big step toward the laboratory re-creation of the “RNA world,” which is generally believed to have preceded modern life forms based on DNA and proteins.

17 Aug 2016

Rice scientists unveil behavior of graphene nanoribbons in solutions

Graphene nanoribbons (GNRs) bend and twist easily in solution, making them adaptable for biological uses like DNA analysis, drug delivery and biomimetic applications, according to scientists at Rice University.

17 Aug 2016

Research opens door to reveal how platelets sense mechanical forces to initiate blood clotting

Using a unique single-molecule force measurement tool, a research team has developed a clearer understanding of how platelets sense the mechanical forces they encounter during bleeding to initiate the cascading process that leads to blood clotting.

17 Aug 2016

MSU scientists show how special genes stay open to fight against infections

A new discovery at Michigan State University has revealed how special genes stay open for business, helping diagram a mechanism that plays a key role in fighting inflammation and infections.

17 Aug 2016

Modifying huntingtin protein protects against behavioral symptoms in Huntington's model mice

There is new hope in the fight against Huntington's disease. Scientists at the Gladstone Institutes discovered that changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease.

16 Aug 2016

G Protein News and Research

New NIST Standard Reference Material helps ensure accurate measurements of HER2 breast cancer gene

New research article reveals global patterns of genetic variation

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

New clinical trial to examine safety of checkpoint inhibitor in pediatric cancer patients

New book from Cold Spring Harbor examines major antibiotics and mechanisms of resistance

Salk researchers identify new mechanism for Alzheimer's risk gene

Novel material heals diabetic wounds faster than standard bandage

Research shines more light on role of proteins in maintaining synaptic transmission

Researchers find potential way to reduce effects of TBI with neuron-targeting nanoparticle

Scientists working on new approach to produce fruit protein far sweeter than sugar

New test holds potential to revolutionise diagnosis of childhood leukaemia

Molecular alarm clock awakens ovules from resting period

TSRI scientists tackle decades-old challenge by re-creating primordial RNA world

Rice scientists unveil behavior of graphene nanoribbons in solutions

Research opens door to reveal how platelets sense mechanical forces to initiate blood clotting

MSU scientists show how special genes stay open to fight against infections

Modifying huntingtin protein protects against behavioral symptoms in Huntington's model mice

Researchers find new way to kill Staphylococcus aureus bacteria

MGH investigators discover key molecules essential for sensing proteasome dysfunction

Computers could be more accurate than pathologists in assessing lung cancer tissues, study shows

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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