Laboratory News and Research

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ACMG issues recommendations on handling of incidental findings in clinical genome, exome sequencing

In a highly anticipated report, landmark recommendations on the handling of incidental findings in clinical genome and exome sequencing are being issued from the American College of Medical Genetics and Genomics.

22 Mar 2013

Salk scientists discover how brain keeps track of similar but distinct memories

Ever find yourself racking your brain on a Monday morning to remember where you put your car keys? When you do find those keys, you can thank the hippocampus, a brain region responsible for storing and retrieving memories of different environments-such as that room where your keys were hiding in an unusual spot.

22 Mar 2013

Researchers develop new approach for HIV vaccine development

Decades of research and three large-scale clinical trials have so far failed to yield an effective HIV vaccine, in large part because the virus evolves so rapidly that it can evade any vaccine-induced immune response.

22 Mar 2013

Researchers identify new substance in olive oil that reduces risk of Alzheimer's disease

The mystery of exactly how consumption of extra virgin olive oil helps reduce the risk of Alzheimer's disease (AD) may lie in one component of olive oil that helps shuttle the abnormal AD proteins out of the brain, scientists are reporting in a new study. It appears in the journal ACS Chemical Neuroscience.

21 Mar 2013

HIV home tests: an interview with Dr Nitika Pant Pai, McGill University

30 years into the HIV epidemic, there is no vaccine in sight. Yet, even though there are fantastic and effective cheap and universally available drugs, and a treatment as prevention strategy is known to work, people do not wish to get tested for HIV! If everyone got tested, and treated, we could have brought the infection under control a long time ago!

21 Mar 2013

Study reveals treatments for pain at site of injury may not always be good enough

Treatments for pain at the site of an injury may not always be good enough, according to a novel study by University of Maryland (UM) scientists reported March 20 in The Journal of Neuroscience.

21 Mar 2013

TSRI receives fund to develop new field test for Onchocerciasis

Philanthropist, businessman and community leader John Moores has given The Scripps Research Institute approximately $2 million to fund the development of a new field test for Onchocerciasis, or river blindness, a parasitic infection that affects tens of millions of people in Africa, Latin America and other tropical regions.

21 Mar 2013

New class of anti-malarial compounds discovered

A group of researchers from 16 institutions around the world has identified a new class of anti-malarial compounds that target multiple stages of the malaria parasite's life cycle.

21 Mar 2013

New biodegradable nanoparticles deliver inflammation-resolving drugs to sites of tissue injury

A multicenter team of researchers, including scientists at Columbia University Medical Center (CUMC), Brigham and Women's Hospital (BWH), Mount Sinai School of Medicine, and Massachusetts Institute of Technology, has developed biodegradable nanoparticles that are capable of delivering inflammation-resolving drugs to sites of tissue injury.

20 Mar 2013

Antagonist drug Emend halts brain tumor growth

New research from the University of Adelaide has shown for the first time that the growth of brain tumors can be halted by a drug currently being used to help patients recover from the side effects of chemotherapy.

20 Mar 2013

German Research Foundation sets up eight new Research Units

The Deutsche Forschungsgemeinschaft is establishing eight new Research Units. This was decided by the DFG Senate during its 2013 March meeting in Bonn.

20 Mar 2013

Study reveals how adolescent brain matures as they sleep

New study conducted by monitoring the brain waves of sleeping adolescents has found that remarkable changes occur in the brain as it prunes away neuronal connections and makes the major transition from childhood to adulthood.

20 Mar 2013

University of Pittsburgh researchers receive NIH grant to develop wearable artificial lung

Each year, nearly 350,000 Americans die of some form of lung disease, with another 150,000 patients needing short- and long-term care. Unfortunately, current breathing-support technologies are cumbersome, often requiring patients to be bedridden and sedated.

20 Mar 2013

Study: Intake of carbohydrate-enriched foods after birth predisposes child to obesity later in life

Consumption of foods high in carbohydrates immediately after birth programs individuals for lifelong increased weight gain and obesity, a University at Buffalo animal study has found, even if caloric intake is restricted in adulthood for a period of time.

20 Mar 2013

Genetic testing services for rare neurological disorders launched by Athena Diagnostics

Athena Diagnostics, a leader in neurological diagnostics, today announced the clinical availability of new genetic tests to aid the detection of several rare neurological disorders, including hereditary neuropathy, neuromuscular disease, epilepsy and certain movement disorders. The lab-developed tests are available through Athena Diagnostics, a business of Quest Diagnostics (NYSE:DGX), the world’s leading provider of diagnostic information services.

From Quest Diagnostics 19 Mar 2013

Dementia diagnostic panel for treatable forms of cognitive impairment launched by Quest Diagnostics

Quest Diagnostics (NYSE: DGX), the world’s leading provider of diagnostic information services, announced the availability of the first clinical test panel for aiding the diagnosis of suspected dementia due to treatable forms of cognitive impairment. The test panel is believed to be the first commercial service from a clinical laboratory to combine several guideline-recommended tests for identifying secondary, treatable causes of dementia as a single blood test and report.

From Quest Diagnostics 19 Mar 2013

Alnylam begins dosing in Phase I clinical trial with ALN-TTRsc for treatment of ATTR

Alnylam Pharmaceuticals a leading RNAi therapeutics company, announced today that it has initiated dosing in its Phase I clinical trial with ALN-TTRsc, an RNAi therapeutic targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR).

19 Mar 2013

A Map of 'Shortcuts' simplifies the hunt for disease-causing genes

Some diseases are caused by single gene mutations. Current techniques for identifying the disease-causing gene in a patient produce hundreds of potential gene candidates, making it difficult for scientists to pinpoint the single causative gene.

19 Mar 2013

Research provides better understanding of microbiological factors of periodontitis

Microbes from the human mouth are telling Oak Ridge National Laboratory scientists something about periodontitis and more after they cracked the genetic code of bacteria linked to the condition.

19 Mar 2013

Research reveals immortality gene mutation plays pivotal role in brain tumors, other cancers

Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research led by Duke Cancer Institute.

19 Mar 2013

Laboratory News and Research

ACMG issues recommendations on handling of incidental findings in clinical genome, exome sequencing

Salk scientists discover how brain keeps track of similar but distinct memories

Researchers develop new approach for HIV vaccine development

Researchers identify new substance in olive oil that reduces risk of Alzheimer's disease

HIV home tests: an interview with Dr Nitika Pant Pai, McGill University

Study reveals treatments for pain at site of injury may not always be good enough

TSRI receives fund to develop new field test for Onchocerciasis

New class of anti-malarial compounds discovered

New biodegradable nanoparticles deliver inflammation-resolving drugs to sites of tissue injury

Antagonist drug Emend halts brain tumor growth

German Research Foundation sets up eight new Research Units

Study reveals how adolescent brain matures as they sleep

University of Pittsburgh researchers receive NIH grant to develop wearable artificial lung

Study: Intake of carbohydrate-enriched foods after birth predisposes child to obesity later in life

Genetic testing services for rare neurological disorders launched by Athena Diagnostics

Dementia diagnostic panel for treatable forms of cognitive impairment launched by Quest Diagnostics

Alnylam begins dosing in Phase I clinical trial with ALN-TTRsc for treatment of ATTR

A Map of 'Shortcuts' simplifies the hunt for disease-causing genes

Research provides better understanding of microbiological factors of periodontitis

Research reveals immortality gene mutation plays pivotal role in brain tumors, other cancers

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