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New research suggests novel combination approach to fight against gliomas

"Devastating" and "dismal." That's how leading researchers describe the present outlook for malignant brain tumors. The median survival rate for patients with glioblastoma multiforme, or GBM, is a mere 14.2 months.

4 Jan 2017

Study offers new insights into mechanisms underlying action of motor proteins

A study published today offers a new understanding of the complex cellular machinery that animal and fungi cells use to ensure normal cell division, and scientists say it could one day lead to new treatment approaches for certain types of cancers.

4 Jan 2017

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

Research findings on sweat glands have potential to improve methods for culturing skin grafts

As early humans shed the hairy coats of their closest evolutionary ancestors, they also gained a distinct feature that would prove critical to their success: a type of sweat gland that allows the body to cool down quickly. Those tiny glands are enormously useful, allowing us to live in a wide variety of climates, and enabling us to run long distances.

4 Jan 2017

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

Richard Myers, PhD, professor of neurology at Boston University School of Medicine, was recently awarded $100,000 from the Ellison Foundation for research to further study a Parkinson's disease (PD) target.

4 Jan 2017

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study.

3 Jan 2017

Chemical modification improves release and availability of insulin, research shows

Replacing a hydrogen atom by an iodine atom in insulin, the hormone retains its efficacy but is available more rapidly to the organism.

3 Jan 2017

HER2-targeted dendritic cell vaccine shows promise for treating early-stage breast cancer patients

Deregulation and inhibition of the immune system contributes to cancer development. Many therapeutic strategies aim to restimulate the immune system to recognize cancer cells and target them for destruction.

3 Jan 2017

AMPK enzyme plays vital role in enhancing muscle insulin sensitivity after physical activity

ampk Physical activity benefits diabetics and others with insulin resistance. One of the reasons is that a single bout of physical activity increases the effectiveness of insulin.

3 Jan 2017

TSRI researchers develop new approach to find how environmental estrogens impact public health

Breast cancer researchers from the Florida campus of The Scripps Research Institute have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, abnormal reproductive development, including “precocious puberty,” and promote breast cancer.

3 Jan 2017

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

National Institutes of Health researchers have discovered molecular mechanisms that may underlie a woman's susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period.

3 Jan 2017

UM SOM study identifies key Zika proteins as likely suspects for damage

Until it burst onto the scene earlier this year, Zika was an obscure, little-known virus. As a result, scientists know little about how it works.

3 Jan 2017

Massive sequencing and coevolution unveils secrets of human protein interactions

Cells operate like an incredibly well-synchronized orchestra of molecular interactions among proteins. Understanding this molecular network is essential not only to understand how an organism works but also to determine the molecular mechanisms responsible for a multitude of diseases.

30 Dec 2016

Researchers identify possible treatment targets for myelodysplasia syndromes

Cincinnati Children's researchers report in Nature Immunology a new mechanism that controls blood cell function and several possible molecular targets for treating myelodysplasia syndromes (MDS) - a group of pre-malignant disorders in which bone marrow does not produce enough healthy blood cells.

30 Dec 2016

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment--called environmental estrogens--can produce infertility, abnormal reproductive development, including "precocious puberty," and promote breast cancer.

30 Dec 2016

Protein C News and Research

New research suggests novel combination approach to fight against gliomas

Study offers new insights into mechanisms underlying action of motor proteins

How does the brain control appetite?

Research findings on sweat glands have potential to improve methods for culturing skin grafts

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

Chemical modification improves release and availability of insulin, research shows

HER2-targeted dendritic cell vaccine shows promise for treating early-stage breast cancer patients

AMPK enzyme plays vital role in enhancing muscle insulin sensitivity after physical activity

TSRI researchers develop new approach to find how environmental estrogens impact public health

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

UM SOM study identifies key Zika proteins as likely suspects for damage

Massive sequencing and coevolution unveils secrets of human protein interactions

Researchers identify possible treatment targets for myelodysplasia syndromes

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Acute stress can lead to delayed, long-term psychological trauma

A new strategy to fight prostate cancer

New active pharmaceutical ingredient may help against severe forms of testicular cancer

New tool explains how proteins assemble into different liquid and gel-like solid states

"More aggressive" nutrition improves growth and development of tiny premature babies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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