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Older women with chronic health problems more likely to have lower quality of life

Researchers writing in the Journal of the American Geriatrics Society recently learned that older women who are frail, and who have six or more chronic health conditions, are twice as likely to have a lower quality of life compared to women with less than three risk factors.

30 Apr 2016

Frailty, depression symptoms in older adults can affect spouses

Frailty, a condition that affects 10 percent of people aged 65 and older, can make older adults more prone to disability, falls, hospitalization and a shorter lifespan. Recently, researchers writing in the Journal of the American Geriatrics Society examined the effects of frailty and depression on married couples.

30 Apr 2016

Elusive brain receptor may play vital role in death of neurons from neurological diseases

Strokes, seizures, traumatic brain injury and schizophrenia: these conditions can cause persistent, widespread acidity around neurons in the brain. But exactly how that acidity affects brain function isn't well understood.

30 Apr 2016

New oral cancer drugs getting more expensive over time, study shows

New cancer drugs taken in pill form have become dramatically more expensive in their first year on the market compared with drugs launched 15 years ago, a University of North Carolina at Chapel Hill study has found. The findings call into question the sustainability of a system that sets high prices at market entry in addition to rapidly increasing those prices over time.

30 Apr 2016

Men need to brush up on their knowledge of skin cancer

Skin cancer can affect anyone, regardless of age, race or gender. When it comes to skin cancer prevention and detection, however, it seems that men need to brush up on their knowledge.

29 Apr 2016

TJP1 protein could help determine multiple myeloma patients who may best benefit from proteasome inhibitors

A gene known as TJP1 (tight junction protein 1) could help determine which multiple myeloma patients would best benefit from proteasome inhibitors such as bortezomib, as well as combination approaches to enhance proteasome inhibitor sensitivity, according to a study led by The University of Texas MD Anderson Cancer Center.

29 Apr 2016

Understanding how individuals respond to aspirin

Researchers have learned new information about how different people respond to aspirin, a globally prescribed drug in cardioprotection. The research team, led by scientists at Cardiff University in the United Kingdom and including representatives from the University of Alabama at Birmingham and the University of Colorado, identified more than 5,600 lipids — or fats — in blood platelets and gained new insights into how these cells respond to aspirin.

29 Apr 2016

Discovery of shared biological properties among DNA variants may help identify new therapeutic targets

The discovery of shared biological properties among independent variants of DNA sequences offers the opportunity to broaden understanding of the biological basis of disease and identify new therapeutic targets, according to a collaboration between the Perelman School of Medicine at the University of Pennsylvania, the University of Arizona Health Sciences, and Vanderbilt University. The group published their findings this month in npj Genomic Medicine.

29 Apr 2016

Nicotine metabolism linked with chronic alcohol abuse may contribute to poor smoking cessation rates

For smokers who are addicted to alcohol, chronic alcohol abuse may increase the rate of nicotine metabolism and contribute to poor smoking cessation rates. When smokers stop drinking the nicotine metabolism rates decline significantly, according to a study conducted by an international research team led by Roswell Park Cancer Institute. The research was a collaboration of scientists from Roswell Park, the University of California, San Francisco, and the Medical University of Silesia and Center of Addiction Treatment in Poland.

29 Apr 2016

Daily chocolate consumption may improve cardio-metabolic health

A new study published in the British Journal of Nutrition appears to back up the adage that a little of what you fancy does you good.

29 Apr 2016

New class of cancer-driver gene may serve as unique therapeutic targets, biomarkers in TNBC

The discovery of long non-coding RNA (lncRNA) has dramatically changed the understanding of the biology of diseases such as cancer. The human genome contains about 20,000 protein-coding genes - less than 2 percent of the total - but 70 percent of the genome is made into non-gene-encoding RNA.

29 Apr 2016

Cells have ability to perceive their own shapes, new study shows

Can a cell sense its own shape? Working in the Marine Biological Laboratory's Whitman Center, scientists from Dartmouth College developed an ingenious experiment to ask this question. Their conclusion - Yes - is detailed in a recent paper in the Journal of Cell Biology.

29 Apr 2016

Neighbourhood deprivation link to diabetes strengthened

A large study based on a policy of semi-randomised dispersal of refugees within a country supports the notion that living in a deprived neighbourhood can increase people's risk of developing Type 2 diabetes.

29 Apr 2016

Study examines benefits of exercise, behavioral therapy in MS patients

Groundhog Day 1994 is one Linda Friedrich will never forget. That's the day a neurologist told her, "You have multiple sclerosis and there's nothing we can do."

28 Apr 2016

New model can increase active surveillance for low-risk prostate cancer patients

Urologists at University of California, San Diego School of Medicine and Genesis Healthcare Partners have tested a new model of care for patients with low-risk prostate cancer. The evidence-based approach uses best practices to appropriately select and follow patients to avoid disease overtreatment. Results of the three-year study are now published online in the journal of Urology.

28 Apr 2016

Maternal exposure to air pollution increases risk of long-term health problems in children

Even small amounts of air pollution appear to raise the risk of a condition in pregnant women linked to premature births and lifelong neurological and respiratory disorders in their children, new Johns Hopkins Bloomberg School of Public Health research suggests.

28 Apr 2016

Healthy adults who work after retirement age may be at lower risk of death, study shows

Working past age 65 could lead to longer life, while retiring early may be a risk factor for dying earlier, a new study from Oregon State University indicates.

28 Apr 2016

New study reveals increased risk of dementia in patients with rosacea

A new study has uncovered an increased risk of dementia--in particular Alzheimer's disease--in patients with rosacea. Importantly, the risk was highest in older patients and in patients where rosacea was diagnosed by a hospital dermatologist. The findings are published in the Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society.

28 Apr 2016

MBCT could be effective treatment to prevent recurrence of depression

The largest meta-analysis so far of Mindfulness-Based Cognitive Therapy (MBCT) for recurrent depression has found that MBCT is an effective treatment option that can help prevent the recurrence of major depression. The study used anonymised individual patient data from nine randomized trials of MBCT. It suggests that for the millions of people who suffer recurrent depression it provides a treatment choice and an alternative or addition to other approaches such as maintenance anti-depressants.

28 Apr 2016

Study highlights significant burden of migraine on family activities

The debilitating pain and disability of migraine also attacks the emotional, social and financial fabric of a family, according to a new study conducted by researchers at Montefiore Headache Center, Albert Einstein College of Medicine, affiliated with the Uniformed Services University of the Health Sciences, Vedanta Research, the Mayo Clinic and Allergan plc. The findings were published today in Volume 91, Issue 5 of Mayo Clinic Proceedings.

28 Apr 2016

Education News and Research

Older women with chronic health problems more likely to have lower quality of life

Frailty, depression symptoms in older adults can affect spouses

Elusive brain receptor may play vital role in death of neurons from neurological diseases

New oral cancer drugs getting more expensive over time, study shows

Men need to brush up on their knowledge of skin cancer

TJP1 protein could help determine multiple myeloma patients who may best benefit from proteasome inhibitors

Understanding how individuals respond to aspirin

Discovery of shared biological properties among DNA variants may help identify new therapeutic targets

Nicotine metabolism linked with chronic alcohol abuse may contribute to poor smoking cessation rates

Daily chocolate consumption may improve cardio-metabolic health

New class of cancer-driver gene may serve as unique therapeutic targets, biomarkers in TNBC

Cells have ability to perceive their own shapes, new study shows

Neighbourhood deprivation link to diabetes strengthened

Study examines benefits of exercise, behavioral therapy in MS patients

New model can increase active surveillance for low-risk prostate cancer patients

Maternal exposure to air pollution increases risk of long-term health problems in children

Healthy adults who work after retirement age may be at lower risk of death, study shows

New study reveals increased risk of dementia in patients with rosacea

MBCT could be effective treatment to prevent recurrence of depression

Study highlights significant burden of migraine on family activities

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