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Understanding SARS-CoV-2-induced systemic amyloidosis

A new study proposed that inflammation combined with aggregates of amyloidogenic peptides of SARS-CoV-2 S proteins might induce systemic amyloidosis.

21 Dec 2021

Study analyzes the role of circular RNA in ALS pathology

Amyotrophic lateral sclerosis, known as ALS, is a neurodegenerative disorder which affects motor neurons. These are the neuronal cells responsible for muscle innervation, whose degenerations leads to progressive paralysis culminating with motor and respiratory failure.

21 Dec 2021

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

A new study posted to the bioRxiv* preprint server aimed to demonstrate whether the loss of the QTQTN motif attenuates SARS-CoV-2 replication in respiratory cells in vitro and pathogenesis in hamsters.

20 Dec 2021

Nanostructured polymeric scaffolds accelerate neuronal differentiation of neural stem cells

Collaboration between different UPV/EHU departments has achieved a promising advance for future cell therapy: nanostructured scaffolds based on bioresorbable polymers and graphene derivatives that induce aligned migration and accelerate the neuronal differentiation of neural stem cells.

20 Dec 2021

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

Researchers conduct a comprehensive in vitro analysis of relatively unexplored host immune responses during SARS-CoV-2 infection.

20 Dec 2021

Traditional medicinal plant alleviates malaria symptoms in mice

The active plant ingredient anemonin could provide a new approach in the treatment of malaria. It was identified by researchers from Ethiopia and Germany in a buttercup that is traditionally used in some African countries as a medicinal plant to treat malaria.

20 Dec 2021

Impact of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military personnel

A new study helps to explain the rapid spread of the Delta variant and provides the impetus to increase control measures including vaccine boosters and social distancing requirements.

20 Dec 2021

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

A new study evaluates the repRNA vaccine expressing the SARS-CoV-2 spike protein for the B.1.1.7 and B.1.351 variants in mice and hamsters.

19 Dec 2021

Echinacea purpurea may help prevent respiratory tract infections during COVID-19 pandemic

A new study describes the results of using an extract of the medicinal plant Echinacea purpurea to treat non-severe cases of COVID-19.

19 Dec 2021

Scientists create a new method to efficiently barcode individual cells

Scientists have developed a pioneering new technique to barcode individual cells more accurately and efficiently - which could help pave the way for quicker disease diagnosis.

18 Dec 2021

Impact of SARS-CoV-2 Omicron mutations on the use of therapeutic antibodies in COVID-19 treatment

Researchers investigated the mutations reported in the Omicron variant and its likely impact on the use of therapeutic antibodies in COVID-19 treatment as well as on vaccinated individuals.

17 Dec 2021

Capability of BNT162b2 vaccine given in 2 or 3 doses to neutralize SARS-CoV-2 Omicron

The team observed that three doses of the BNT162b2 (Pfizer-BioNTech) mRNA vaccine are required to mount an effective antibody response against the Omicron variant.

16 Dec 2021

Experimental and computational synergy considered a promising approach in COVID-19 patients

Thanks to the large amount of -omics data becoming increasingly available, sophisticated computational models are developed for new fields such as immunology and the predictions they generate will help identify key molecules in inflammatory processes.

16 Dec 2021

in vitro News and Research

Understanding SARS-CoV-2-induced systemic amyloidosis

Study analyzes the role of circular RNA in ALS pathology

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

Nanostructured polymeric scaffolds accelerate neuronal differentiation of neural stem cells

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

Traditional medicinal plant alleviates malaria symptoms in mice

Impact of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military personnel

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

Echinacea purpurea may help prevent respiratory tract infections during COVID-19 pandemic

Scientists create a new method to efficiently barcode individual cells

Impact of SARS-CoV-2 Omicron mutations on the use of therapeutic antibodies in COVID-19 treatment

Capability of BNT162b2 vaccine given in 2 or 3 doses to neutralize SARS-CoV-2 Omicron

Experimental and computational synergy considered a promising approach in COVID-19 patients

Neutralization potency of COVID-19 vaccine boosters against SARS-CoV-2 variant pseudoviruses

Human monoclonal antibody protects against SARS-CoV-2 and SARS-CoV in vivo

Study suggests Omicron can be neutralized by BNT162b2 recipient sera optimally after three vaccine doses

Children conceived with assisted reproductive techniques are not at risk of poor psychiatric health

T-cell immune response in previously infected and vaccinated individuals effective against SARS-CoV-2 Omicron variant

BrainGlobe; An Open-Source Platform for Neuroscientists

Engineering of brain-mimetic injectable hydrogel scaffolds with self-healing properties

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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