Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Live-cell microscopy reveals internal forces that direct cell migration

Two new studies conducted at the Marine Biological Laboratory (MBL) indicate the way by which cells react to internal forces when they orient, gain traction, and migrate in a particular direction.

11 Dec 2017

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Among younger patients newly diagnosed with chronic lymphocytic leukemia (CLL), treatment with a combination of chemotherapy and a molecularly targeted drug significantly improves response over what is typically seen with chemotherapy alone, according to an investigator-initiated multi-center phase II clinical trial.

11 Dec 2017

Breakthrough research could lead to development of yeast-based protein therapies

It took several years, but a research team headed by Professor Jens Nielsen at Chalmers University of Technology has finally succeeded in mapping out the complex metabolism of yeast cells.

11 Dec 2017

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) patients.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

Salk scientists unravel mystery about how the spinal cord deals with different information

We think of our brain as masterminding all of our actions, but a surprising amount of information related to movement gets processed by our spinal cord.

8 Dec 2017

Study estimates number of Americans with preclinical Alzheimer's or mild cognitive impairment

About 15 million Americans will have either Alzheimer's dementia or mild cognitive impairment by 2060, up from approximately 6.08 million this year, according to a new study by researchers at the UCLA Fielding School of Public Health.

8 Dec 2017

Study finds mechanism of resistance to checkpoint inhibitors and way to reverse it

Researchers have discovered a mechanism of resistance to checkpoint inhibitors and how to reverse it. The biomarker results from the IMvigor210 study are reported at the ESMO Immuno Oncology Congress 2017.

8 Dec 2017

SLU scientists provide promising approach in designing new drugs for DMD

In a paper published in the Nature journal Scientific Reports, Saint Louis University researchers report that a new drug reduces fibrosis (scarring) and prevents loss of muscle function in an animal model of Duchenne muscular dystrophy (DMD), providing a promising approach in designing new medications for those suffering from DMD.

8 Dec 2017

Scientists discover how axons in developing visual system stabilize their connections

Scientists at Tokyo Tech have made an important discovery concerning the development of layer-specific axonal connections in the developing visual system of Drosophila flies.

8 Dec 2017

Nutrition labeling has little impact on sodium consumption

Potato chips, frozen pizza, a fast food hamburger- these foods are popular in the American diet and saturated with sodium. Though eating too much can lead to high blood pressure and heart disease, 90 percent of Americans eat more than the recommended amount of sodium per day.

8 Dec 2017

Researchers seek to understand role of novel protein in tumor metastasis

Metastasis, the process in which a tumor spreads to other parts of the body, is responsible for 90% of deaths from tumors. It is the greatest challenge to a cancer patient's survival. Metastatic spread occurs in several steps, these include that tumor cells become mobile and cross into and out of blood vessels.

8 Dec 2017

Research brings scientists one step closer to understanding development of ALS

University of Michigan-led research brings scientists one step closer to understanding the development of neurodegenerative disorders such as ALS.

8 Dec 2017

Gene therapy shows promising effect against blood clots, study states

A new study conducted in the Children's Hospital Of Philadelphia (CHOP) reported positive results in a phase 1/2 clinical trial for the inherited bleeding disorder hemophilia B.

8 Dec 2017

Common fungus has significant impact on mosquitoes' ability to transmit dengue virus

A species of fungus that lives in the gut of some Aedes aegypti mosquitoes increases the ability of dengue virus to survive in the insects, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

7 Dec 2017

Malaria parasite employs active strategy to deceive the immune system

Global efforts to eradicate malaria are crucially dependent on scientists' ability to outsmart the malaria parasite. And Plasmodium falciparum is notoriously clever: It is quick to develop resistance against medications and has such a complex life cycle that blocking it effectively with a vaccine has thus far proved elusive.

7 Dec 2017

Research findings offer path for drug discovery to treat hyperaldosteronism

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute, in collaboration with researchers at Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health, identifies a mechanism that explains the development of hyperaldosteronism.

7 Dec 2017

Protein News and Research

Further Reading

Live-cell microscopy reveals internal forces that direct cell migration

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Breakthrough research could lead to development of yeast-based protein therapies

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

Two immunotherapy approaches for multiple myeloma show hope

Salk scientists unravel mystery about how the spinal cord deals with different information

Study estimates number of Americans with preclinical Alzheimer's or mild cognitive impairment

Study finds mechanism of resistance to checkpoint inhibitors and way to reverse it

SLU scientists provide promising approach in designing new drugs for DMD

Scientists discover how axons in developing visual system stabilize their connections

Nutrition labeling has little impact on sodium consumption

Researchers seek to understand role of novel protein in tumor metastasis

Research brings scientists one step closer to understanding development of ALS

Gene therapy shows promising effect against blood clots, study states

Common fungus has significant impact on mosquitoes' ability to transmit dengue virus

Malaria parasite employs active strategy to deceive the immune system

Research findings offer path for drug discovery to treat hyperaldosteronism

Researchers discover how unusually long strands of RNA work in skin cells

Study paves way for new therapeutic strategies to impede growth of virus-induced cancers

Researchers establish function of long RNA strands in skin development and disease

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