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Zika virus causes altered immune responses and brain abnormalities in healthy pig offspring

Zika virus infection in the womb produces altered immune responses and sex-specific brain abnormalities in apparently healthy pig offspring, according to a study published November 14 in the open-access journal PLOS Pathogens by Uladzimir Karniychuk of the University of Saskatchewan, and colleagues.

From PLOS ONE 11 Nov 2019

Health education intervention may promote healthier lifestyle in underserved communities

A unique study conducted in a multi-ethnic, underserved community in New York City shows if young adults are properly taught about heart healthy behaviors and strictly adhere to specific interventions, they may see significant benefits to their cardiovascular health when compared to those who do not have any health education intervention, according to Mount Sinai researchers.

11 Nov 2019

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Impaired liver function during pregnancy may alter gut bacteria composition and increase the risk of obesity in children, according to results presented at The Society for Endocrinology Annual Conference.

11 Nov 2019

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA)

10 Nov 2019

New light on the essential reproductive role of the clitoris

A new study focuses on the role of the clitoris in females, showing that when it is stimulated, it triggers a wave of changes within the rest of the reproductive tract. The outcome of these changes confers on the clitoris not only recreative but also reproductive importance, according to the studies.

10 Nov 2019

Injured veteran almost back to normal after penis and scrotum transplant

An interesting letter in the New England Journal of Medicine on November 7, 2019, describes the successful outcome at one year of a rare genital transplant in a young war veteran who lost most of the lower part of the abdominal wall, the scrotum and both testes, and both legs below the knee, to a bomb blast.

10 Nov 2019

Skin-to-skin contact between mother and baby after C-section has risks

It was widely accepted that putting the newborn baby on the mother’s chest promotes skin-to-skin contact and bonding between the two who share the common experience of birth, and enhances the chances of successful breastfeeding, after a Cesarean section. However, from the viewpoint of anesthesiologists, who oversee the critical part of keeping the mother pain-free yet healthy during the surgical procedure, this introduces unnecessary risks.

10 Nov 2019

Climate change spreading deadly virus in marine mammals

A deadly virus that kills thousands of European harbour seals in the northern Atlantic Ocean has now begun affecting seals, otters and sea lions in the northern Pacific Ocean. This virus is called the phocine distemper virus (PDV) that affects animals alone and does not affect humans.

10 Nov 2019

Study pinpoints new weapon to fight against deadly microbes

Researchers at Monash University have gained insights into how nanoparticles could be used to identify the presence of invasive and sometimes deadly microbes, and deliver targeted treatments more effectively.

10 Nov 2019

Study finds fewer new cases of HCV in HIV-negative men who have sex with PrEP-using men

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found fewer new cases of hepatitis C infection (commonly called HCV), despite very high rates of other sexually-transmitted infections, in HIV-negative men who have sex with men who take pre-exposure prophylaxis (PrEP) treatments.

10 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Diabetic kidney disease remains one of the most intractable complications of diabetes. Progress has been made using glycemic and blood pressure control, but the search continues for improved treatments for the estimated one in four adults with diabetes who has some level of nephropathy and continues at risk for eventual kidney failure.

10 Nov 2019

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.

10 Nov 2019

Vitamin D, fish oil supplements do not help preserve kidney health in people with type 2 diabetes

Supplements of vitamin D and omega-3 fatty acids (often sold as fish oil) do not help people with type 2 diabetes stave off chronic kidney disease, according to findings from the largest clinical study to date of the supplements in this patient population.

10 Nov 2019

Illinois researchers develop lab-on-a-smartphone system to detect infectious diseases

Infectious diseases such as Zika and Dengue remain a top contributor to death and disability across the globe, according to the World Health Organization.

10 Nov 2019

Study reveals safety, efficacy of live zoster vaccine for people taking TNF inhibitors

According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, the live zoster virus vaccine is safe for people who are currently receiving tumor necrosis factor inhibitor (TNFi) biologic therapies for various indications.

10 Nov 2019

Study finds novel potential approach to treat type 2 diabetes

The protein adipsin, which is produced in body fat, helps protect insulin-secreting cells called pancreatic beta cells from destruction in type 2 diabetes, according to a new study by researchers at Weill Cornell Medicine and NewYork-Presbyterian.

9 Nov 2019

UC researcher finds new treatment option for liver transplant patients

A drug commonly used to treat both asthma and inflammatory bowel disease, budesonide, may also be useful as an anti-organ rejection medication for liver transplant patients leading to fewer serious side effects than the most commonly used therapy, according to a University of Cincinnati researcher.

9 Nov 2019

Investigational vaccine protects macaques against four types of hemorrhagic fever viruses

Scientists funded by the National Institutes of Health have developed an investigational vaccine that protected cynomolgus macaques against four types of hemorrhagic fever viruses endemic to overlapping regions in Africa.

8 Nov 2019

Substitution of glutamates for salt can reduce sodium intake, study shows

Promising results from a new study published in the journal Nutrients add to accumulating evidence that glutamates such as monosodium glutamate can be used to reduce sodium in the food supply.

8 Nov 2019

Blood News and Research

Zika virus causes altered immune responses and brain abnormalities in healthy pig offspring

Health education intervention may promote healthier lifestyle in underserved communities

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

New light on the essential reproductive role of the clitoris

Injured veteran almost back to normal after penis and scrotum transplant

Skin-to-skin contact between mother and baby after C-section has risks

Climate change spreading deadly virus in marine mammals

Study pinpoints new weapon to fight against deadly microbes

Study finds fewer new cases of HCV in HIV-negative men who have sex with PrEP-using men

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

Vitamin D, fish oil supplements do not help preserve kidney health in people with type 2 diabetes

Illinois researchers develop lab-on-a-smartphone system to detect infectious diseases

Study reveals safety, efficacy of live zoster vaccine for people taking TNF inhibitors

Study finds novel potential approach to treat type 2 diabetes

UC researcher finds new treatment option for liver transplant patients

Investigational vaccine protects macaques against four types of hemorrhagic fever viruses

Substitution of glutamates for salt can reduce sodium intake, study shows

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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