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Novel detection method for retinoblastoma

A retinoblastoma is a dangerous cancer often occurring in very young children, under 2, which can cause blindness or the loss of the eye. The tumor is a diffuse, gluey mass spread all over the eye. It also spreads easily. As a result of this, direct biopsy is impossible, unlike with most other tumors. Instead, eye examination by ophthalmologists (eye specialists) and ultrasound imaging are needed to make a diagnosis.

5 Nov 2019

Penn researchers tag CAR T cells with imaging markers to monitor cancer therapy

With CAR T cell therapy, a patient's own immune cells are genetically modified and inserted back into the body to find and kill cancer. This form of immunotherapy has already revolutionized some cancer treatments, but once the CAR T cells are inside a patient, where do they go? How do doctors know that they have successfully reached their target and that they are continuing to fight disease weeks, months, or even years later?

5 Nov 2019

Even a short run could reduce risk of death by 27 percent

A new study has shown that even short runs regularly could help lower the risk of death due to any cause. This came from pooled data from a large number of participants.

5 Nov 2019

Some common youth sports injuries can be avoided, Mayo Clinic experts say

As fall and winter sports are in full swing, youth athletics will see a rise in injuries. Tens of millions of children and teens participate in organized sports, and more than 3.5 million sports injuries occur every year.

5 Nov 2019

Researchers identify potential drug targets for glioblastoma

Researchers at Karolinska Institutet in Sweden have identified 10 tumor-specific potential drug targets for the brain tumor glioblastoma. The results are presented in the scientific journal Cell Reports.

5 Nov 2019

Tumor cell plasticity counts during cancer metastasis

Cancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality.

5 Nov 2019

Researchers propose genetic testing and continued management of identical twin kidney transplants

Using U.S. transplant registry data, clinical researchers at the University of Pittsburgh School of Medicine found that kidney transplants between identical twins have high success rates, but also high rates of immunosuppressant use.

5 Nov 2019

Study defies decades-old patient eligibility guidelines for bariatric surgery

Weight-loss surgery has long been shown to improve or resolve diabetes, reduce heart attacks and stroke and produce significant weight loss, but the operation has generally been restricted by health insurers to people with severe obesity, which means about 75 to 100 pounds overweight or a body mass index (BMI) of 35 or higher.

5 Nov 2019

Large waist circumference may be a risk factor for obesity-related dementia

A new study has shown that that visceral obesity may be associated with an increased risk for dementia among older individuals.

5 Nov 2019

MD Anderson and Takeda announce agreement to develop off-the-shelf CAR NK-cell therapy platform

The University of Texas MD Anderson Cancer Center and Takeda Pharmaceutical Company Limited today announced an exclusive license agreement and research agreement to develop cord blood-derived chimeric antigen receptor-directed natural killer (CAR NK)-cell therapies, 'armored' with IL-15, for the treatment of B-cell malignancies and other cancers.

5 Nov 2019

Metabolic surgery patients two times less likely to have recurrent and fatal heart attacks

Metabolic surgery patients with a history of coronary artery disease were about two times less likely to have a recurrent and fatal heart attack or develop systolic heart failure compared to closely matched patients who did not have the surgery, according to a new study from Cleveland Clinic Florida researchers who presented their findings today at the 36th American Society for Metabolic and Bariatric Surgery Annual Meeting at ObesityWeek 2019.

5 Nov 2019

Cancer risk reduces to half with over 20% weight loss in post- bariatric surgery patients

Patients with severe obesity who had bariatric or weight-loss surgery and lost more than 20% of their total weight were 50% less likely to develop cancer compared to patients who did not have as much weight loss after surgery, according to a new study presented today by Oregon Health & Science University researchers at the 36th American Society for Metabolic and Bariatric Surgery Annual Meeting at ObesityWeek 2019.

5 Nov 2019

FDA keeps brand-name drugs on a fast path to market ― despite manufacturing concerns

After unanimously voting to recommend a miraculous hepatitis C drug for approval in 2013, a panel of experts advising the Food and Drug Administration gushed about what they'd accomplished.

5 Nov 2019

Signs of frailty could be identified through a new assessment

Signs of frailty, and the risks it brings, could be identified in young and old people alike through a new assessment developed in a study led by researchers at the University of Strathclyde.

5 Nov 2019

Mother-infant free-play interactions have positive effect on child's obesity risk trajectories

The deleterious effects that obesity has on an individual's health and the difficulty of reversing it in adults are well-known, ranging from diabetes and heart disease to cancer.

5 Nov 2019

High waist circumference linked to increased obesity-related dementia risk

Waist circumference is a more accurate indicator of abdominal visceral fat level than body mass index in the elderly, according to a report published in Obesity, the flagship journal of The Obesity Society.

5 Nov 2019

Record number of Legionnaires’ cases in 2018 risk lives, cause cleanup headaches

Cases of Legionnaires' disease reached a record high in 2018 — a more than eight-fold increase since the numbers began to climb nearly two decades ago.

5 Nov 2019

Humanizing cell cultures

Today we know the function and metabolism of any mammalian cell depends on its environment. Such cells have long been cultured under conditions consisting of a basal medium with added nutritional serum. This, however, is not an accurate replica of the cell’s environment within the human body.

5 Nov 2019

Adding weight loss counseling to group visits provides extra health benefits to diabetics

For people with difficult-to-control diabetes, adding intensive weight management counseling to group medical visits provided extra health benefits beyond improved blood-sugar control, according to a study led by researchers at the Duke Diet & Fitness Center and the Department of Veterans Affairs.

4 Nov 2019

UK aims to lead with cutting-edge radiation therapy

The UK is all set to launch its run into the future as the undisputed leader in the field of personalized and effective radiation therapy. The proposal is undergirded by a whopping £56 million, which will be used to set up and fund advanced radiation therapy research by a new collaborative setup, Cancer Research UK RadNet, over five years. This is the largest sum ever invested by this organization into radiotherapy research.

4 Nov 2019

Blood News and Research

Novel detection method for retinoblastoma

Penn researchers tag CAR T cells with imaging markers to monitor cancer therapy

Even a short run could reduce risk of death by 27 percent

Some common youth sports injuries can be avoided, Mayo Clinic experts say

Researchers identify potential drug targets for glioblastoma

Tumor cell plasticity counts during cancer metastasis

Researchers propose genetic testing and continued management of identical twin kidney transplants

Study defies decades-old patient eligibility guidelines for bariatric surgery

Large waist circumference may be a risk factor for obesity-related dementia

MD Anderson and Takeda announce agreement to develop off-the-shelf CAR NK-cell therapy platform

Metabolic surgery patients two times less likely to have recurrent and fatal heart attacks

Cancer risk reduces to half with over 20% weight loss in post- bariatric surgery patients

FDA keeps brand-name drugs on a fast path to market ― despite manufacturing concerns

Signs of frailty could be identified through a new assessment

Mother-infant free-play interactions have positive effect on child's obesity risk trajectories

High waist circumference linked to increased obesity-related dementia risk

Record number of Legionnaires’ cases in 2018 risk lives, cause cleanup headaches

Humanizing cell cultures

Adding weight loss counseling to group visits provides extra health benefits to diabetics

UK aims to lead with cutting-edge radiation therapy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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