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U-M researcher awarded $600,000 grant for study of progesterone in treatment of children with TBI

A University of Michigan researcher has received a two-year, $600,000 grant to plan a randomized controlled study of progesterone for the treatment of traumatic brain injury in children.

17 Nov 2010

Combination of CT scans effective in diagnosing coronary artery disease

Heart imaging specialists at Johns Hopkins have shown that a combination of CT scans that measure how much blood is flowing through the heart and the amount of plaque in surrounding arteries are just as good as tests that are less safe, more complex and more time-consuming to detect coronary artery disease and its severity.

17 Nov 2010

Predictive Biosciences, Epigenomics extend GSTP1 licensing agreement for prostate cancer

Epigenomics AG , the cancer diagnostics company, and Predictive Biosciences, a commercial stage, fully-integrated developer of novel molecular diagnostic cancer assays and a provider of anatomic pathology laboratory products and services, today announced that they have extended their licensing agreement for the prostate cancer biomarker GSTP1, originally signed in April 2009.

17 Nov 2010

PrecisionMed enrolls first subject in Multiple Sclerosis Registry

PrecisionMed Inc. today announced at the Society for Neuroscience annual meeting in San Diego, enrollment of the first subject into the PrecisionMed Multiple Sclerosis (MS) Registry. The PrecisionMed MS Registry is a biological sample bank of DNA and serial RNA, CSF, serum and plasma associated with serial clinical testing utilizing PrecisionMed's clinical data procurement and storage capabilities.

17 Nov 2010

Study: EGFR inhibtion may help treat triple negative breast cancer

Scientists believe they may have found a new target for treating triple negative breast cancer - one of the more difficult breast cancers to treat successfully and for which there is no targeted therapy at present.

17 Nov 2010

UCSF, Pfizer announce partnership to accelerate translation of biomedical research

UCSF and Pfizer, Inc. have formed a new partnership to accelerate the translation of biomedical research into effective new medications and therapies for patients.

16 Nov 2010

MLL purchases Access Array, EP1 Systems for high-throughput deep-resequencing analysis

Fluidigm Corporation announced today that MLL Munich Leukemia Laboratory has purchased Access Array and EP1 Systems. The Access Array System is being used in combination with Roche's 454 GS FLX and GS Junior sequencing instruments, enabling high-throughput targeted deep-resequencing analyses.

16 Nov 2010

New mechanism breaks drug resistance in ovarian cancer

Drug resistance is a major obstacle in curing ovarian cancer but new research from the Centenary Institute has discovered a treatment that kills ovarian cancer cells in a new way that can break the resistance mechanism.

16 Nov 2010

UC San Diego researchers receive NIH grant to develop scaffolds

University of California, San Diego NanoEngineers won a grant from the National Institutes of Health (NIH) to develop the tools to manufacture biodegradable frames around which heart tissues functional blood vessels included will grow.

16 Nov 2010

Stanford Hospital offers iPads to enhance patient experience

Instead of television, Stanford Hospital is offering some patients a more high-tech form of entertainment, iPads. As part of a pilot program, the hospital has outfitted its catheterization and angiography laboratory with five of the tablet computers. They've been loaded with movies, books and games. They can also connect to the Internet through the hospital's wireless network.

16 Nov 2010

New stem cell-infused patch improves heart function after myocardial infarction

University of Cincinnati (UC) researchers have found that applying a stem cell-infused patch together with overexpression of a specific cell instruction molecule promoted cell migration to damaged cardiac tissue following heart attack and resulted in improved function in animal models.

16 Nov 2010

Researchers develop human cell-based model of Rett syndrome

A groundbreaking study published Friday in the leading scientific journal, Cell, revealed that a team of investigators had successfully generated nerve cells using skin cells from four individuals with Rett syndrome. The study, funded in part by IRSF, was led by Dr. Alysson Muotri at the University of California, San Diego--a leading researcher in the stem cell field.

16 Nov 2010

Children's Hospital pediatric immunologist collaborates with European gene therapy researchers to study WAS syndrome

A pediatric immunologist at The Children's Hospital of Philadelphia collaborated with European gene therapy researchers who achieved marked clinical improvements in two young children with Wiskott-Aldrich syndrome, a very rare but often severe immunodeficiency disorder.

16 Nov 2010

OtoSCOPE method offers single-run genetic testing for hearing loss

Pinpointing the exact genetic cause of inherited deafness has always involved sequencing one gene at a time, a process that can take up to a year and cost roughly $1,000 per gene. It would cost around $75,000 to test all known deafness causing genes using this approach. Now University of Iowa researchers working with colleagues at Baylor College of Medicine have developed a test that can screen all of the genes known to cause deafness in a single run, in one to three months and for about $2,000.

16 Nov 2010

Fisetin slows onset of motor problems, delays death in three models of Huntington's disease: Study

Fisetin, a naturally occurring compound found in strawberries and other fruits and vegetables, slows the onset of motor problems and delays death in three models of Huntington's disease, according to researchers at the Salk Institute for Biological Studies. The study, published in the online edition of Human Molecular Genetics, sets the stage for further investigations into fisetin's neuroprotective properties in Huntington's and other neurodegenerative conditions.

16 Nov 2010

Bayer presents results from Phase III ROCKET AF trial for atrial fibrillation at American Heart Association

Bayer today announced the results from the pivotal, double-blind Phase III, ROCKET AF trial. In the study, rivaroxaban demonstrated superiority to warfarin in reducing the risk of stroke and non-CNS systemic embolism in patients with atrial fibrillation (AF).

16 Nov 2010

Sen. Lugar highlights potential bioterrorism threat posed by unsecured medical facilities in East Africa

Senator Dick Lugar on Friday said that poorly secured medical laboratories in East African countries, which host insurgent groups linked to Al Qaeda, are vulnerable to bioterrorism, Agence France-Presse reports.

16 Nov 2010

RBC boosting drugs may undermine breast cancer treatment with Herceptin

Red-blood-cell-boosting drugs used to treat anemia may undermine breast cancer treatment with Herceptin, a targeted therapy that blocks the cancer-promoting HER2 protein, researchers from The University of Texas MD Anderson Cancer Center report in the Nov. 16 edition of Cancer Cell.

16 Nov 2010

NPR reports on dengue vaccine progress

NPR's Shots blog examines progress in the search for a vaccine to protect against the dengue virus. WHO estimates that 2.5 billion people worldwide are at risk of getting dengue, and most of them are in Asia and Latin America, the blog writes.

16 Nov 2010

GenturaDx to showcase IDbox molecular diagnostic system at AMP 2010

GenturaDx will display its proprietary molecular diagnostic system, the IDbox System, at the annual meeting of the Association for Molecular Pathology (AMP) in San Jose, Calif. on November 17 – 20, 2010. The IDbox System incorporates all aspects of its proprietary, real-time PCR testing from sample preparation through result generation in a single-use cassette.

15 Nov 2010

Laboratory News and Research

U-M researcher awarded $600,000 grant for study of progesterone in treatment of children with TBI

Combination of CT scans effective in diagnosing coronary artery disease

Predictive Biosciences, Epigenomics extend GSTP1 licensing agreement for prostate cancer

PrecisionMed enrolls first subject in Multiple Sclerosis Registry

Study: EGFR inhibtion may help treat triple negative breast cancer

UCSF, Pfizer announce partnership to accelerate translation of biomedical research

MLL purchases Access Array, EP1 Systems for high-throughput deep-resequencing analysis

New mechanism breaks drug resistance in ovarian cancer

UC San Diego researchers receive NIH grant to develop scaffolds

Stanford Hospital offers iPads to enhance patient experience

New stem cell-infused patch improves heart function after myocardial infarction

Researchers develop human cell-based model of Rett syndrome

Children's Hospital pediatric immunologist collaborates with European gene therapy researchers to study WAS syndrome

OtoSCOPE method offers single-run genetic testing for hearing loss

Fisetin slows onset of motor problems, delays death in three models of Huntington's disease: Study

Bayer presents results from Phase III ROCKET AF trial for atrial fibrillation at American Heart Association

Sen. Lugar highlights potential bioterrorism threat posed by unsecured medical facilities in East Africa

RBC boosting drugs may undermine breast cancer treatment with Herceptin

NPR reports on dengue vaccine progress

GenturaDx to showcase IDbox molecular diagnostic system at AMP 2010

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