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Gene transfer reduces and stabilizes plaque and decreases inflammation

A plaque-fighting gene - studied in various forms by researchers at the Cedars-Sinai Heart Institute for 18 years - has now been transferred intravenously to lab mice bred to model atherosclerosis (clogged arteries) in humans. Studies show the gene transfer reduced and stabilized plaque and decreased inflammation, key factors in cutting the risk of heart disease.

18 Nov 2010

EDP Biotech introduces new blood test for detecting early-stage colon cancer at Medica trade fair

The future of colon cancer screening may be surprisingly simple. ColoMarker, an innovative blood test to detect the early stages of colon cancer is generating plenty of attention from a wide audience, including from some of the world's leading researchers in cancer biomarkers and gastrointestinal medicine.

18 Nov 2010

8 states get better grade on 2010 March of Dimes Premature Birth Report Card

Eight states earned a better grade on the 2010 March of Dimes Premature Birth Report Card and 32 others and the District of Columbia saw their preterm birth rates improve.

17 Nov 2010

Pre-term births are leading cause of health problems in infants and cost the U.S. over $26 billion annually

The Center for Healthcare Research & Transformation (CHRT) based at the University of Michigan today released its Prematurity Issue Brief that shows pre-term births --- births at less than 37 weeks of gestation --- are the leading cause of health problems in infants and estimated to cost the U.S. more than $26 billion annually. In addition, the report shows that a black infant in Michigan is 70% more likely to be born prematurely than an infant of any other race.

17 Nov 2010

Elsevier launches new module for scientific community

Elsevier , a world-leading publisher of scientific, technical and medical information products and services, today announced the launch of SciVerse Applications beta, a new module within the SciVerse platform that will empower the scientific community to develop and share customized solutions that advance the search and discovery process through its marketplace and developer network.

17 Nov 2010

Study shows asthma drugs can treat aortic aneurysm

A new study from the Swedish medical university Karolinska Institutet shows that asthma drugs are a potential treatment for aortic aneurysm. These drugs, which block cysteinyl-leukotrienes, could reduce the break down of vessel wall tissue and the dilation of the aortic wall, and thus the risk of its rupturing.

16 Nov 2010

Merrion prepares Phase III study for Orazol in breast cancer treatment

After recent consultation with the FDA in November 2010, Merrion is preparing for its Phase III study for Orazol. If successful, the Phase III study will allow a new drug application for Orazol to be made under the FDA's abbreviated approval procedure section 505(b)(2) using a single Phase III study. The study will compare Orazol against placebo as an adjuvant breast cancer treatment with a primary endpoint of Disease Free Survival of patients with breast cancer.

16 Nov 2010

Leaders speak at Partnership for Maternal, Newborn and Child Health conference

Education for women is the most important factor for positively influencing the health of women and children, Indian President Pratibha Patil said on Saturday at a meeting in New Delhi of The Partnership for Maternal, Newborn & Child Health (PMNCH), IANS/Sify News reports. "Education is a powerful driver of health. The relationship between poverty, lack of education and limited access to health services, is well recognised," Patil said at the start of the two-day conference (11/13).

16 Nov 2010

Fisetin slows onset of motor problems, delays death in three models of Huntington's disease: Study

Fisetin, a naturally occurring compound found in strawberries and other fruits and vegetables, slows the onset of motor problems and delays death in three models of Huntington's disease, according to researchers at the Salk Institute for Biological Studies. The study, published in the online edition of Human Molecular Genetics, sets the stage for further investigations into fisetin's neuroprotective properties in Huntington's and other neurodegenerative conditions.

16 Nov 2010

Temple University professionals focus on community viral load to combat HIV

World AIDS Day is December 1, but healthcare professionals at Temple University work year-round to combat HIV by focusing on reducing the community viral load, or the severity of HIV in a particular group. This approach has become widespread in the past two years, and it is still evolving and undergoing evaluation.

15 Nov 2010

NIMH intramural researcher to receive National Medal of Science

National Institutes of Health intramural researcher Mortimer Mishkin, Ph.D., will be awarded the National Medal of Science at a White House ceremony later this month. Mishkin is chief of the National Institute of Mental Health's (NIMH) Section on Cognitive Neuroscience, and acting chief of its Laboratory of Neuropsychology.

15 Nov 2010

CytomX awarded $488,000 as grant under QTDP Program

CytomX Therapeutics, a biotechnology company focused on the development of proteolytically activated antibodies, today announced the receipt of two grants totaling more than $488,000 from the Qualifying Therapeutic Discovery Project (QTDP) Program. The grants are directed toward the company's lead preclinical programs targeting colon, head and neck, pancreatic and triple-negative breast cancers and glioblastoma multiforme (GBM).

12 Nov 2010

Progressive report recommends new practices to manage errors in HIT systems

An original and progressive report on health information technology (HIT) vendors, their customers and patients, published online today, makes ground-breaking recommendations for new practices that target the reduction or elimination of tensions that currently mar relationships between many HIT vendors and their customers, specifically with regard to indemnity and error management of HIT systems.

12 Nov 2010

BioWorld Today features ImmunGene's pipeline of next generation armed antibodies for cancer

ImmunGene, Inc., a privately held drug development company focused on targeted antibody therapeutics with numerous anti-cancer functions built into a single therapy, announced today that a profile of the company and its pipeline is featured in the November 21 issue of BioWorld Today in the NewCo section.

11 Nov 2010

FDA identifies promising steps to enhance safety of CT scans

The U.S. Food and Drug Administration has been investigating reports that patients undergoing computed tomography (CT) brain perfusion scans were accidently exposed to excess radiation. The FDA found that when properly used, the CT scanners did not malfunction. Instead, it is likely that the improper use of the scanners resulted in these overdoses. However, the FDA has identified a series or promising steps to enhance the safety of these procedures. These steps could reduce the likelihood of radiation overexposure in the event of improper use of the CT scanners.

11 Nov 2010

Scientists find way to overcome limitations of ultrasound imaging

University of California, Berkeley, scientists have found a way to overcome one of the main limitations of ultrasound imaging the poor resolution of the picture.

11 Nov 2010

Researchers find text messages to HIV patients improve adherence, health outcomes in Kenya trial

Using mobile-phone text messages to remind HIV patients to take their dose of life-saving medications can give a major boost to drug adherence, according to an innovative trial in Kenya unveiled on Tuesday, Agence France-Presse reports.

10 Nov 2010

Article shows link between maternal cigarette smoking during pregnancy, SIDS

The link between maternal cigarette smoking during pregnancy and Sudden Infant Death Syndrome may relate to the negative effects of nicotine on the development of brain centers that regulate breathing, according to an article in the recent issue of Pediatric Allergy, Immunology, and Pulmonology, a peer-reviewed journal published by Mary Ann Liebert, Inc.

10 Nov 2010

Researchers to determine levels of stroke risk in patients with narrowed brain arteries

Neurological researchers at Rush University Medical Center are part of a multicenter, National Institutes of Health (NIH) study to determine the levels of stroke risk and stroke recurrence in patients with narrowed brain arteries.

10 Nov 2010

Forceps delivery can pose risk to mother and child

Forceps might be a better instrument than a vacuum cup for assisting a successful birth, but new mothers might experience more trauma and complications after a forceps delivery, according to a new review of studies.

10 Nov 2010