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NanoTemper Technologies employs game-changing solutions for faster drug development

Following a successful inaugural meeting in 2014, the 2nd Drug Discovery Forum (DDF) took place on May 8–11, 2016 at the Westin Grand Hotel in Munich.

From NanoTemper Technologies 2 Sep 2016

NanoTemper Technologies to highlight applications of MST, nanoDSF in drug discovery at Biopharma Workshop 2016

NanoTemper Technologies offers MicroScale Thermophoresis (MST) and nanoDSF technology to analyze these parameters in an easy and precise way. To meet the increasing demand for high-throughput applications and unattended operation, NanoTemper Technologies provides fully automated MST and nanoDSF platforms — and combinations of both.

From NanoTemper Technologies 2 Sep 2016

Researchers uncover molecular differences between African and Asian strain of Zika virus infections

Scientists have revealed molecular differences between how the African and Asian strains of Zika virus infect neural progenitor cells.

1 Sep 2016

Low levels of diastolic blood pressure linked to heart damage risk

By analyzing medical records gathered over three decades on more than 11,000 Americans participating in a federally funded study, researchers at Johns Hopkins Medicine say they have more evidence that driving diastolic blood pressure too low is associated with damage to heart tissue.

1 Sep 2016

Research findings of protein may form foundation for new approach to antibiotics

Researchers have made the first-ever detailed, atomic-level images of a peroxiredoxin, which has revealed a peculiar characteristic of this protein and might form the foundation for a new approach to antibiotics.

1 Sep 2016

Blood cancer treatment linked to distinct increase in molecular age of immune cells

Certain cancer treatments are known to take a toll on patients, causing side effects like fatigue, nausea and hair loss. Now, scientists are investigating whether some treatments can cause another long-term side effect: premature aging of important disease-fighting cells.

1 Sep 2016

Researchers reveal novel link between nicotine and inflammation

An Umeå-based team in collaboration with US researchers reveals a new link between nicotine and inflammation.

1 Sep 2016

LJI researchers reveal unanticipated way by which neutrophils defend against invading pathogens

As an arm of the innate immune system, white blood cells called neutrophils form the first line of defense against invading pathogens.

31 Aug 2016

Disrupting bacteria's motility can stop infections

When looking at bacteria, you typically see also flagella: long hairs that protrudes from the bacteria's body.

31 Aug 2016

Researchers identify new gene for type 2 diabetes at well-established genomic location

Gene researchers have used sophisticated scientific tools to reveal a new gene for type 2 diabetes at a well-established genomic location.

31 Aug 2016

Research findings could lead to new biomarker for early stages of tumor development

To treat or not to treat? That is the question researchers at the Department of Energy's Lawrence Berkeley National Laboratory hope to answer with a new advance that could help doctors and their cancer patients decide if a particular therapy would be worth pursuing.

31 Aug 2016

Mitosis study identifies new potential target for cancer therapy

Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to cancer. Their hope now is that the detailed new characterization of the interaction will make it a target for exploring a new cancer therapy.

31 Aug 2016

Scientists generate functional tissue-engineered liver from adult stem and progenitor cells

A research team led by investigators at The Saban Research Institute of Children's Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells.

31 Aug 2016

Special review highlights benefits of using botulinum neurotoxin for treating facial wrinkles

Botox and other botulinum neurotoxin (BoNT) products are widely known for their use in treating facial wrinkles--but they can also be used to treat a wide range of non-cosmetic problems.

31 Aug 2016

Researchers discover protein that plays role in onset of type 1 diabetes

A new study reveals a counterintuitive cellular strategy that may protect insulin-producing cells from destruction during type 1 diabetes.

31 Aug 2016

Simple diagnostic algorithm to assess pulmonary embolism risk can help reduce rate of CTPA imaging

Patients with suspected pulmonary embolism (PE) often undergo computed tomography pulmonary angiography (CTPA) to confirm or exclude the diagnosis.

31 Aug 2016

New stem-cell model of heart tissue unravels mechanisms linked to hypertrophic cardiomyopathy

Using advanced stem cell technology, scientists from the Icahn School of Medicine at Mount Sinai have created a model of a heart condition called hypertrophic cardiomyopathy (HCM) — an excessive thickening of the heart that is associated with a number of rare and common illnesses, some of which have a strong genetic component.

31 Aug 2016

Investigational biomarker surpasses current gold standard test for identifying brain shunt infections

In a study of children with brain shunts at Children's of Alabama, a University of Alabama at Birmingham investigational biomarker outperformed the current "gold standard" test for detecting bacterial infections in the shunts.

30 Aug 2016

Endogenous cannabinoid plays crucial role in activating spermatozoa for fertilization

During fertilization, a sperm must first fuse with the plasma membrane and then penetrate the female egg in order to penetrate it.

30 Aug 2016

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

In an effort to determine if stem cell therapy can prevent or improve a condition called "diabetic foot" caused by poor blood flow in patients with diabetes, a team of researchers in China has found that transplanting human placenta-derived mesenchymal stem cells (MSCs) into rats modeled with diabetes can affect blood vessel growth, potentially improving blood flow and preventing critical limb ischemia (CLI), a condition that results in diabetic foot and frequently leads to amputation.

30 Aug 2016

Protein C News and Research

NanoTemper Technologies employs game-changing solutions for faster drug development

NanoTemper Technologies to highlight applications of MST, nanoDSF in drug discovery at Biopharma Workshop 2016

Researchers uncover molecular differences between African and Asian strain of Zika virus infections

Low levels of diastolic blood pressure linked to heart damage risk

Research findings of protein may form foundation for new approach to antibiotics

Blood cancer treatment linked to distinct increase in molecular age of immune cells

Researchers reveal novel link between nicotine and inflammation

LJI researchers reveal unanticipated way by which neutrophils defend against invading pathogens

Disrupting bacteria's motility can stop infections

Researchers identify new gene for type 2 diabetes at well-established genomic location

Research findings could lead to new biomarker for early stages of tumor development

Mitosis study identifies new potential target for cancer therapy

Scientists generate functional tissue-engineered liver from adult stem and progenitor cells

Special review highlights benefits of using botulinum neurotoxin for treating facial wrinkles

Researchers discover protein that plays role in onset of type 1 diabetes

Simple diagnostic algorithm to assess pulmonary embolism risk can help reduce rate of CTPA imaging

New stem-cell model of heart tissue unravels mechanisms linked to hypertrophic cardiomyopathy

Investigational biomarker surpasses current gold standard test for identifying brain shunt infections

Endogenous cannabinoid plays crucial role in activating spermatozoa for fertilization

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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