Protein C News and Research

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Study finds age-dependent differences in expression of allergy to dust mites

In adults with a house dust mite allergy, a cascade of inflammatory signals on the surface of the airways leads to airway remodeling.

26 Aug 2016

TSRI study sheds light on how mitochondrial calcium can affect learning and memory

While calcium's importance for our bones and teeth is well known, its role in neurons—in particular, its effects on processes such as learning and memory—has been less well defined.

26 Aug 2016

New biomaterial allows scientists to study how stem cells sense stiffness of surrounding environment

A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment, found a team led by Robert Mauck, PhD, the Mary Black Ralston Professor for Education and Research in Orthopaedic Surgery, in the Perelman School of Medicine at the University of Pennsylvania.

26 Aug 2016

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive.

26 Aug 2016

New camera technology paired with electron microscope allows biologists to see tiny cellular components

Using a new, lightning-fast camera paired with an electron microscope, Columbia University Medical Center scientists have captured images of one of the smallest proteins in our cells to be "seen" with a microscope.

26 Aug 2016

New study looks to saliva of humans and primates to gain insights into evolution

There's no need to reinvent the genetic wheel. That's one lesson of a new study that looks to the saliva of humans, gorillas, orangutans, macaques and African green monkeys for insights into evolution.

25 Aug 2016

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

A study shows that stimulating the production of interleukin-17A (IL-17A), one of the cytokines released by cells of the immune system, can be an effective strategy for the treatment of visceral leishmaniasis, considered one of the six most important parasitic diseases affecting humans.

25 Aug 2016

Protein complex could play key role in natural development of stem cells into healthy blood cells

A group of proteins best known for helping to activate all mammalian genes has been found to play a particularly commanding role in the natural development of specialized stem cells into healthy blood cells, a process known as hematopoiesis.

25 Aug 2016

Cedars-Sinai study identifies metabolic enzyme that alerts the body to invading bacteria

Biomedical investigators at Cedars-Sinai have identified an enzyme found in all human cells that alerts the body to invading bacteria and jump-starts the immune system.

25 Aug 2016

People with high levels of four biomarkers may have increased risk for stroke

People with high levels of four biomarkers in the blood may be more likely to develop a stroke than people with low levels of the biomarkers, according to a study published in the August 24, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

25 Aug 2016

Raising brain protein alleviates symptoms of Alzheimer's disease in mouse model

Boosting levels of a specific protein in the brain alleviates hallmark features of Alzheimer's disease in a mouse model of the disorder, according to new research published online August 25, 2016 in Scientific Reports.

25 Aug 2016

Medical students developing smart helmet to help diagnose concussions

A smart helmet that can help diagnose concussions in football players is being developed by medical students at Texas Tech University Health Sciences Center El Paso.

25 Aug 2016

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

An atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects through their actions at different sites on the calcium channel molecule.

25 Aug 2016

Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Special RNA molecules called long non-coding RNAs (lncRNAs) are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders, according to research led by Jorge Henao-Mejia, MD, PhD, an assistant professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania.

25 Aug 2016

Type of bacteria in the gut may increase or decrease risk of developing celiac disease

About 40 per cent of the population have a genetic disposition to celiac disease, but only about one per cent develop the autoimmune condition when exposed to gluten, and this could be promoted by the type of bacteria present in the gut.

25 Aug 2016

HMS study reveals key instigator of nerve cell damage in ALS patients

Scientists from Harvard Medical School have identified a key instigator of nerve cell damage in people with amyotrophic lateral sclerosis, or ALS, a progressive and incurable neurodegenerative disorder.

25 Aug 2016

UT Southwestern researchers discover protein that can promote healthful breakdown of fat

Researchers at UT Southwestern Medical Center have found that a protein often located on the surface of fat droplets within cells - and especially abundant in the muscles of endurance athletes - can kick-start the more efficient and healthful breakdown of fat.

25 Aug 2016

Researchers identify brain circuit that helps take major developmental step despite nutritional stress

When we go hungry, we have the ability to ignore the urge to eat such that we can carry out the task at hand. It has long been known that the brain is involved in such decisions.

24 Aug 2016

New imaging technique may help detect amyloid-related heart failure

A type of heart failure caused by a build-up of amyloid can be accurately diagnosed and prognosticated with an imaging technique, eliminating the need for a biopsy, according to a multicenter study led by researchers at Columbia University Medical Center.

24 Aug 2016

Assigning barcode to stem cells makes it possible to monitor large blood cell populations

By assigning a barcode to stem cells, researchers at Lund University in Sweden have made it possible to monitor large blood cell populations as well as individual blood cells, and study the changes over time.

24 Aug 2016

Protein C News and Research

Study finds age-dependent differences in expression of allergy to dust mites

TSRI study sheds light on how mitochondrial calcium can affect learning and memory

New biomaterial allows scientists to study how stem cells sense stiffness of surrounding environment

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

New camera technology paired with electron microscope allows biologists to see tiny cellular components

New study looks to saliva of humans and primates to gain insights into evolution

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

Protein complex could play key role in natural development of stem cells into healthy blood cells

Cedars-Sinai study identifies metabolic enzyme that alerts the body to invading bacteria

People with high levels of four biomarkers may have increased risk for stroke

Raising brain protein alleviates symptoms of Alzheimer's disease in mouse model

Medical students developing smart helmet to help diagnose concussions

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Type of bacteria in the gut may increase or decrease risk of developing celiac disease

HMS study reveals key instigator of nerve cell damage in ALS patients

UT Southwestern researchers discover protein that can promote healthful breakdown of fat

Researchers identify brain circuit that helps take major developmental step despite nutritional stress

New imaging technique may help detect amyloid-related heart failure

Assigning barcode to stem cells makes it possible to monitor large blood cell populations

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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