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Preventing neutrophils from producing NETs can accelerate wound healing in diabetic mice

One of the body's tools for fighting off infection in a wound may actually slow down the healing process, according to new research by a team of Harvard University, Boston Children's Hospital, and Penn State University scientists.

19 Jun 2015

PAH diagnosis delayed for adult congenital heart disease patients

Pulmonary arterial hypertension is often not diagnosed in adult patients with congenital heart disease until 6 years or more after their symptoms first appear, research shows.

17 Jun 2015

Heparin market in Europe estimated to reach USD 3,148.0 million by 2022

According to a new market report published by Transparency Market Research Heparin Market - Europe Industry Analysis, Size, Share, Growth, Trends and Forecast, 2014 - 2022" the Heparin Market Europe was valued at USD 2,004.5 million in 2013 and is estimated to reach USD 3,148.0 million by 2022 growing with a CAGR of 5.2% from 2014 to 2022.

17 Jun 2015

Accurexa seeks FDA clearance to market BranchPoint device

Accurexa Inc., a biotechnology company focused on developing and commercializing novel neurological therapies, announced on Monday that it has filed a submission with the U.S. FDA for 510(k) clearance to market its BranchPoint device.

17 Jun 2015

Scientists find way to accelerate wound healing in diabetic mice

One of the body's own tools for preventing wound infections may actually interfere with wound healing, according to new research from Boston Children's Hospital. In a study published online in Nature Medicine, scientists from the hospital's Program in Cellular and Molecular Medicine found they could speed up wound healing in diabetic mice by keeping immune cells called neutrophils from producing bacteria-trapping neutrophil extracellular traps (NETs).

15 Jun 2015

Juniper announces enrollment of first patient in COL-1077 Phase II trial to reduce pain during endometrial biopsy

Juniper Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development of therapeutics for women's health, announced today the first patient has been enrolled in a Phase II clinical trial of COL-1077, a 10% lidocaine bioadhesive gel that is intended as an acute-use anesthetic during minimally invasive gynecologic procedures.

15 Jun 2015

Novartis announces FDA approval of Promacta for treatment of children with chronic ITP

Novartis announced today that the US Food and Drug Administration has approved Promacta (eltrombopag) for the treatment of children six years and older with chronic immune thrombocytopenia (ITP) who have had an insufficient response to corticosteroids, immunoglobulins or splenectomy. Promacta was approved by the FDA in 2008 for use in adult patients with the same condition.

15 Jun 2015

Study shows that women with endometriosis at increased risk of miscarriage, ectopic pregnancy

Women with endometriosis are at an increased risk of miscarriage and ectopic pregnancy, according to results of a huge nationwide study presented today. Moreover, women with a history of endometriosis whose pregnancies progressed beyond 24 weeks were found to be at a higher than average risk of complications, including haemorrhage (ante- and postpartum) and preterm birth.

15 Jun 2015

Researchers show how a new drug speeds tissue regeneration in animal models

The concept sounds like the stuff of science fiction: take a pill, and suddenly new tissues grow to replace damaged ones. Researchers at Case Western Reserve and UT Southwestern Medical Center this week announced that they have taken significant steps toward turning this once-improbable idea into a vivid reality.

12 Jun 2015

Daily dose of aspirin effective at blocking breast tumor growth

"Take two aspirin and call me in the morning" has been the punchline for countless jokes. Could it also be good advice for cancer patients? A lab study to appear in the July 2015 issue of Laboratory Investigation found that a daily dose of aspirin was effective at blocking breast tumor growth. Previous studies have already shown a similar effect on colon, gastrointestinal, prostate, and other cancers.

12 Jun 2015

Dietary compounds in milk-based products may protect against cardiovascular risk

The Maillard reaction is a chemical reaction between amino acids and reducing sugars that results in browned foods like seared steaks and toasted bread. When proteins and sugars are mixed together and heated, new chemical compounds are formed. Some are responsible for new flavors and some, according to a new study published in the Journal of Dairy Science, may protect us against cardiovascular disease.

11 Jun 2015

Data from statewide quality collaborative helps surgeons to reduce rates of serious trauma complication

As health insurers place more emphasis on paying for quality outcomes rather than for specific services provided by doctors and hospitals, several quality improvement programs have been developed as a way to help health care providers identify problem areas and share best practices. While some studies have evaluated how well these quality improvement programs achieve their goals, not many have focused on the area of trauma care.

11 Jun 2015

Men benefit from ultrasound screening for abdominal aortic aneurysms

Men benefit from one-time screening for abdominal aortic aneurysms via ultrasound. Studies provide proof that their risk of dying is reduced, the abdominal aorta ruptures less often, and emergency surgery can be avoided more often. Far fewer data are available for women and they show no relevant differences between the groups investigated.

11 Jun 2015

Apitope's ATX-F8-117 granted FDA Orphan Drug Designation for treatment of haemophilia A patients

Apitope, the drug discovery and development company focused on disease-modifying treatments that reinstate immune tolerance, announced today that pre-clinical product candidate ATX-F8-117 has been granted Orphan Drug Status by the US Food and Drug Administration for the prevention or treatment of inhibitors in haemophilia A patients with inhibitors or at the risk of producing inhibitors.

9 Jun 2015

Designing infectious disease forecasting models to predict dengue epidemics

Dengue viruses are on the move. Spread among humans by mosquitoes, and across geographic boundaries through travel, the virus affects up to an estimated 390 million people every year around the world. In the U.S., recent outbreaks have occurred in Florida, Texas, Hawaii, and Puerto Rico. Scientists know one of the best ways to reduce the impact of the disease is to prepare healthcare providers by forecasting epidemics before they happen.

8 Jun 2015

Updated SOGC guidelines include FIBRISTAL as only approved medical treatment for uterine fibroids

The Society for Obstetrics and Gynecology of Canada has issued updated guidelines for the management of uterine fibroids (uterine leiomyomas), which now include the first and only approved medical treatment for uterine fibroids: FIBRISTAL (ulipristal acetate).

4 Jun 2015

Investigators patent novel technique for detecting carcinomas in oral mucosa

Malignant tumours of the oral cavity are the sixth leading cause of cancer-related deaths worldwide. As such, a fast and accurate diagnosis is key to maximising the probability of successful treatment and the hope and quality of life of patients.

4 Jun 2015

Blood research could improve treatment for injured soldiers on the battlefield

Blood research conducted by biomedical engineers from The University of Texas at San Antonio College of Engineering, in collaboration with the Blood Research Program of the U.S. Army Institute of Surgical Research, could change the way injured soldiers are treated on the battlefield.

4 Jun 2015

LMU cardiologists study new approach to inhibit atherosclerotic plaque-induced platelet activation

Blood clots often form when lipid-rich plaques on the inner surface of arteries rupture and platelets aggregate at the site of injury. Cardiologists from Ludwig-Maximilians-Universitaet in Munich have now compared the effects of two new platelet aggregation inhibitors.

4 Jun 2015

Essential Medical to highlight MANTA Large Bore closure system at 2015 Jefferies Global Healthcare Conference

Essential Medical, Inc., a privately held medical device company, announced today that it has been invited to speak at the 2015 Jefferies Global Healthcare Conference in New York city on June 4th.

3 Jun 2015

Bleeding News and Research

Preventing neutrophils from producing NETs can accelerate wound healing in diabetic mice

PAH diagnosis delayed for adult congenital heart disease patients

Heparin market in Europe estimated to reach USD 3,148.0 million by 2022

Accurexa seeks FDA clearance to market BranchPoint device

Scientists find way to accelerate wound healing in diabetic mice

Juniper announces enrollment of first patient in COL-1077 Phase II trial to reduce pain during endometrial biopsy

Novartis announces FDA approval of Promacta for treatment of children with chronic ITP

Study shows that women with endometriosis at increased risk of miscarriage, ectopic pregnancy

Researchers show how a new drug speeds tissue regeneration in animal models

Daily dose of aspirin effective at blocking breast tumor growth

Dietary compounds in milk-based products may protect against cardiovascular risk

Data from statewide quality collaborative helps surgeons to reduce rates of serious trauma complication

Men benefit from ultrasound screening for abdominal aortic aneurysms

Apitope's ATX-F8-117 granted FDA Orphan Drug Designation for treatment of haemophilia A patients

Designing infectious disease forecasting models to predict dengue epidemics

Updated SOGC guidelines include FIBRISTAL as only approved medical treatment for uterine fibroids

Investigators patent novel technique for detecting carcinomas in oral mucosa

Blood research could improve treatment for injured soldiers on the battlefield

LMU cardiologists study new approach to inhibit atherosclerotic plaque-induced platelet activation

Essential Medical to highlight MANTA Large Bore closure system at 2015 Jefferies Global Healthcare Conference

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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