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Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Researchers recently conducted a study to identify host factors affecting cellular interactions of the SARS-CoV-2 spike protein.

16 Nov 2021

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

A new study has described the molecular basis of the neutralization potency and breadth of nanobodies.

16 Nov 2021

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

A recent study investigates histone mimicry as a mechanism by SARS-CoV-2 for disrupting epigenetic regulation to evade host cell responses to infection.

15 Nov 2021

NanoTCE technology shows promise for treatment of acute myeloid leukemia

Oncotarget published "Nanoparticle T cell engagers for the treatment of acute myeloid leukemia" which reported that Acute myeloid leukemia (AML) is the most common type of leukemia and has a 5-year survival rate of 25%.

12 Nov 2021

Xanthohumol as a potent pan-inhibitor for various coronaviruses

Researchers from China reported the results of their study aimed at finding an effective Mpro inhibitor since Mpro is the best drug target to fight SARS-CoV-2 infection.

12 Nov 2021

EKF Diagnostics acquires ADL Health molecular diagnostic testing laboratory

EKF Diagnostics, the global in vitro diagnostics company, announces that it has acquired Advanced Diagnostic Laboratory LLC, a Texas based PCR-focused testing laboratory certified under the Clinical Laboratory Improvement Amendments for high-complexity molecular diagnostics testing.

From EKF Diagnostics 12 Nov 2021

New therapy harnesses "dancing molecules" to reverse paralysis, repair tissue after spinal cord injuries

Northwestern University investigators have developed a new injectable therapy that harnesses "dancing molecules" to reverse paralysis and repair tissue after severe spinal cord injuries.

11 Nov 2021

Immunity following COVID-19 vaccination and natural infection in India

The researchers evaluated immune response markers in a cross-section of people from the Indian state of West Bengal, including those vaccinated with either Covishield or Covaxin, the unvaccinated cohort, and the naturally infected.

11 Nov 2021

First detection of SARS-CoV-2 remdesivir resistance in an immunocompromised patient

A research group from the US (led by experts from Yale University School of Medicine) recently presented a case of an immunocompromised female patient with acquired deficiency of B lymphocytes who subsequently developed a protracted course of the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

10 Nov 2021

Stenoparib effectively inhibits SARS-CoV-2 variants in vitro

A new study assesses the antiviral activity of stenoparib against four SARS-CoV-2 strains.

10 Nov 2021

Identifying an important protein for motor coordination

News-Medical speaks to Professor Jorge Ruas about how he has identified an important protein involved in motor coordination.

10 Nov 2021

Current understanding of the link between COVID-19 and cardiovascular disease

A review published in Chemo-Biological Interactions has focused on the prevalence of COVID-19 in CVD patients associated with ACE2 mechanisms.

10 Nov 2021

Ion channel mechanosensor plays a key role in regulating the speed of skin wound healing

PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound healing by researchers at the University of California, Irvine.

10 Nov 2021

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

BioIVT, a leading provider of research models and services for drug and diagnostic development, is hosting a webinar in which researchers will discuss how they used a sandwich-cultured human hepatocyte (SCHH) model to investigate the drug-drug interaction (DDI) potential of bempedoic acid, a drug that was recently approved to treat hypercholesterolemia.

9 Nov 2021

SARS-CoV-2 infection regulates protein arginylation

A new study explores the role of arginylation during SARS-CoV-2 infection.

9 Nov 2021

CN Bio and iiCON announce COVID-19 research collaboration

CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced a research collaboration with the Infection Innovation Consortium (iiCON), a global collaborative infectious disease R&D programme, to validate the next generation of COVID-19 research tools.

From CN Bio 9 Nov 2021

Hemin as a potential therapy for COVID-19

The current study explores the antiviral activity of HO-1 induced by hemin against SARS-CoV-2 and attempts to describe the mechanism of its anti-viral action.

8 Nov 2021

SARS-CoV-2 Nsp1 deletions affect protein stability and translation inhibition

A new study discusses the purification of various Nsp1 proteins isolated from several mutated variants of SARS-CoV-2.

8 Nov 2021

Study finds SARS-CoV-2 infection of endothelial cells unlikely

Researchers from the University of Queensland have investigated whether infection of endothelial cells with SARS-CoV-2 is possible.

8 Nov 2021

Pacific oyster as a weapon against SARS-CoV-2

According to an article published in the journal Reviews in Medical Virology, the effectiveness of mollusc-derived antiviral agents has been proven in many different laboratory and animal studies, while its efficacy against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has also been proposed by recent in silico studies.

7 Nov 2021