Laboratory News and Research

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Scientists use patient cells to generate human model of Huntington's

Scientists at the Gladstone Institutes and an international team of researchers have generated a human model of Huntington's disease-directly from the skin cells of patients with the disease.

29 Jun 2012

New laboratory model for Huntington's disease

Cedars-Sinai scientists have joined with expert colleagues around the globe in using stem cells to develop a laboratory model for Huntington's disease, allowing researchers for the first time to test directly on human cells potential treatments for this fatal, inherited disorder.

29 Jun 2012

Swine-flu deaths far greater than reported

The true number of deaths from the 2009 H1N1 “swine flu” pandemic may be 15 times higher than the number confirmed by laboratory testing and previously reported to the World Health Organization, study findings indicate.

28 Jun 2012

Program linking paramedics in the field to patients' pre-existing health information wins honors

The nation's first and only program linking paramedics in the field to patients' pre-existing health information -- enabling emergency workers to make more informed treatment decisions and to transport patients to the most appropriate facility -- has been recognized by the prestigious Computerworld Honors Program.

28 Jun 2012

UTMB researchers improve existing experimental vaccine for Rift Valley fever virus

University of Texas Medical Branch researchers have significantly improved an existing experimental vaccine for Rift Valley fever virus, making possible the development of a more effective defense against the dangerous mosquito-borne pathogen.

28 Jun 2012

TB research finds body’s own response helps TB bacteria survive

Inhibiting a key immune response in mice during initial multi-drug treatment for tuberculosis could — paradoxically — shorten treatment time for the highly contagious lung infection according to new research from Johns Hopkins Children’s Center and the Center for TB Research. Shorter duration of drug therapy is key, researchers say, to increase treatment compliance for the growing global health threat posed by the disease.

28 Jun 2012

UH receives federal grants to pursue projects related to prostate cancer, diabetes and obesity

Researchers at the University of Houston (UH) have been awarded more than $862,000 in federal grants to pursue projects related to prostate cancer, diabetes and obesity. The U.S. Department of Defense (DOD) and National Institutes of Health (NIH) will fund two new prostate cancer projects, while a third NIH grant will support diabetes and obesity research in the UH Center for Nuclear Receptors and Cell Signaling (CNRCS).

28 Jun 2012

Nanosphere receives FDA marketing approval for Verigene GP Blood Culture Nucleic Acid Test

The U.S. Food and Drug Administration today allowed marketing of the first nucleic acid test that can identify 12 different bacterial types known to cause bloodstream infections.

28 Jun 2012

Data from Infinity’s IPI-145 pre-clinical study on inflammatory diseases

Infinity Pharmaceuticals, Inc. today reported preclinical data for IPI-145, the company's oral inhibitor of phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma. The data demonstrate potent PI3K-delta and -gamma inhibition in biochemical, cellular and whole blood assays and activity in multiple preclinical models of inflammatory disease, including rheumatoid arthritis and asthma.

28 Jun 2012

Powerful new technique can manipulate the building-block molecules of organic chemistry

Scientists at The Scripps Research Institute have developed a powerful new technique for manipulating the building-block molecules of organic chemistry. The technique enables chemists to add new functional molecules to previously hard-to-reach positions on existing compounds-making it easier for them to generate new drugs and other organic chemicals.

28 Jun 2012

New compound could treat certain types of genetic disorders in muscles

Scientists at UCLA have identified a new compound that could treat certain types of genetic disorders in muscles. It is a big first step in what they hope will lead to human clinical trials for Duchenne muscular dystrophy.

28 Jun 2012

U-M-built microsystem measures trace amounts of air contaminants in homes

A lab-on-a-chip technology that measures trace amounts of air contaminants in homes was successfully field-tested by researchers at the University of Michigan.

28 Jun 2012

Health Canada approves AutoGenomics’ INFINITI PGx testing system

AutoGenomics, a leader in providing automated, molecular microarray testing solutions, announced today that they have received their first Health Canada Medical Device Class III approvals for their automated INFINITI Pharmacogenomic (PGx) testing system.

28 Jun 2012

Registry proves invaluable for fibromuscular dysplasia patients

A patient registry is proving invaluable in cataloging the clinical features, symptoms, severity, and outcomes of fibromuscular dysplasia (FMD), a non-inflammatory vascular disease that can cause narrowing of arteries in the carotid (neck) and renal (kidney) arteries, which can result in headache, strokes, and aneurysms.

27 Jun 2012

Magnet guides iron-loaded cells to specific damaged sites in the heart

Optimal stem cell therapy delivery to damaged areas of the heart after myocardial infarction has been hampered by inefficient homing of cells to the damaged site. However, using rat models, researchers in France have used a magnet to guide cells loaded with iron oxide nanoparticles to key sites, enhancing the myocardial retention of intravascularly delivered endothelial progenitor cells.

27 Jun 2012

Implantable sensor technology and cartilage scaffolding systems for bone and joint repair

A group of biomedical engineering researchers have cited recent advances in implantable sensor technology and cartilage scaffolding systems as major developments in the use of engineered cartilage for bone and joint repair.

27 Jun 2012

Diet enriched with curcumin and DHA can promote neuroprotection in chronic SCI

Researchers from the Department of Neurosurgery at the David Geffen School of Medicine and the Department of Integrative Biology and Physiology at UCLA have found that a diet enriched with docosahexaenoic acid (DHA), an omega-3 fatty acid, and curcumin, a component of the Indian spice turmeric, can protect the injured spinal cord and minimize the clinical and biochemical effects of spinal cord myelopathy in rats.

27 Jun 2012

Patient registry yields new data that is crucial for early diagnosis and treatment of FMD

27 Jun 2012

Apple iPad 2 can affect programmable shunt valve in children with hydrocephalus

Researchers at the University of Michigan have found that the Apple iPad 2 can interfere with settings of magnetically programmable shunt devices, which are often used to treat children with hydrocephalus.

27 Jun 2012

Two major organizations partner in new vendor-neutral health IT innovation network

Two major non-commercial health information technology organizations are working together in a new vendor-neutral health IT innovation network designed to stimulate development of new ideas and shorten the time required to bring new solutions into practice.

27 Jun 2012

Laboratory News and Research

Scientists use patient cells to generate human model of Huntington's

New laboratory model for Huntington's disease

Swine-flu deaths far greater than reported

Program linking paramedics in the field to patients' pre-existing health information wins honors

UTMB researchers improve existing experimental vaccine for Rift Valley fever virus

TB research finds body’s own response helps TB bacteria survive

UH receives federal grants to pursue projects related to prostate cancer, diabetes and obesity

Nanosphere receives FDA marketing approval for Verigene GP Blood Culture Nucleic Acid Test

Data from Infinity’s IPI-145 pre-clinical study on inflammatory diseases

Powerful new technique can manipulate the building-block molecules of organic chemistry

New compound could treat certain types of genetic disorders in muscles

U-M-built microsystem measures trace amounts of air contaminants in homes

Health Canada approves AutoGenomics’ INFINITI PGx testing system

Registry proves invaluable for fibromuscular dysplasia patients

Magnet guides iron-loaded cells to specific damaged sites in the heart

Implantable sensor technology and cartilage scaffolding systems for bone and joint repair

Diet enriched with curcumin and DHA can promote neuroprotection in chronic SCI

Patient registry yields new data that is crucial for early diagnosis and treatment of FMD

Apple iPad 2 can affect programmable shunt valve in children with hydrocephalus

Two major organizations partner in new vendor-neutral health IT innovation network

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