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Mood stabilizers may decrease negative symptoms in psychiatric patients with specific genotype

A drug prescribed to many patients with schizophrenia or bipolar disorder may decrease negative symptoms for people with a certain variant of the COMT gene, suggests a new study from researchers at Columbia University Medical Center.

14 Sep 2016

Research offers new insights into underlying mechanisms of deadly cystic fibrosis

A minor hiccup in the sequence of a human gene can have devastating impacts on health. Such flaws cause cystic fibrosis (CF), a disease affecting the lungs and other vital organs, often leading to death by the age of 30.

9 Sep 2016

Research sheds new light on how human organ systems develop

For the first time, the precise way individual human organs and tissue develop has been mapped - providing new insight into how genetic disorders can occur during the crucial early phase of development.

1 Sep 2016

Research findings could lead to new biomarker for early stages of tumor development

To treat or not to treat? That is the question researchers at the Department of Energy's Lawrence Berkeley National Laboratory hope to answer with a new advance that could help doctors and their cancer patients decide if a particular therapy would be worth pursuing.

31 Aug 2016

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

A study in The Journal of Cell Biology by scientists at the University of Massachusetts Medical School reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool.

30 Aug 2016

Studying mutant peptides may help detect weaknesses in tumor cells

Researchers from MIPT, the Institute of Biomedical Chemistry, the Institute for Energy Problems of Chemical Physics, and the Research Institute of Physico-Chemical Medicine have presented an algorithm to detect mutant proteins based on mass spectrometry data and the results of exome sequencing.

29 Aug 2016

Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Clinical trials and translational medicine have certainly given people hope and rapid pathways to cures for some of mankind's most troublesome diseases, but now is not the time to overlook the power of basic research, says UC Santa Barbara neuroscientist Kenneth S. Kosik.

27 Aug 2016

Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Diabetes heightens the risk of vascular damage to heart and limbs, and impairs the ability to repair damage with new growth of blood vessels, called angiogenesis.

26 Aug 2016

Curbing immune system infighting could make treatment more effective for pancreatic cancer

Internal conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer.

25 Aug 2016

HMS study reveals key instigator of nerve cell damage in ALS patients

Scientists from Harvard Medical School have identified a key instigator of nerve cell damage in people with amyotrophic lateral sclerosis, or ALS, a progressive and incurable neurodegenerative disorder.

25 Aug 2016

New study may offer vital clues to understanding how Zika virus affects the developing brain

In a very severe, genetic form of microcephaly, stem cells in the brain fail to divide, according to a new Columbia University Medical Center study that may provide important clues to understanding how the Zika virus affects the developing brain.

24 Aug 2016

Tel Aviv University researchers unravel how melanoma spreads to distant organs

In a landmark discovery, researchers at Tel Aviv University have unraveled the metastatic mechanism of melanoma, the most aggressive of all skin cancers.

23 Aug 2016

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely.

18 Aug 2016

Neuropathic pain could be significantly reduced by targeting brain cells

Neuropathic pain - which affects more than 1 million Americans - could be reduced or even eliminated by targeting brain cells that are supposed to provide immunity but, in some instances, do the opposite, causing chronic pain that could last a lifetime.

8 Aug 2016

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

Long before Zika virus made it a household word, the birth defect called microcephaly puzzled scientists and doctors -- even as it changed the lives of the babies born with it during the pre-Zika era.

8 Aug 2016

Scientists develop novel multifunctional platform to integrate imaging and photo-induced cancer therapy

Physicists from The University of Texas at Arlington are leading a multidisciplinary project with The University of Texas Southwestern Medical Center in Dallas and The University of Texas MD Anderson Cancer Center in Houston to develop a new multifunctional platform that can integrate imaging and photo-induced cancer therapy in a single, portable device.

5 Aug 2016

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Reprogramming of the molecular pathways underlying normal metabolism is essential for T cell infection-fighting function and for the immune system to form a "memory" of the microbes it has already encountered. But exactly how metabolism in exhausted T cells is maintained in chronic infections and cancer is a missing element in this line of research.

3 Aug 2016

Cell Biology News and Research

Mood stabilizers may decrease negative symptoms in psychiatric patients with specific genotype

Research offers new insights into underlying mechanisms of deadly cystic fibrosis

Research sheds new light on how human organ systems develop

Research findings could lead to new biomarker for early stages of tumor development

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

Studying mutant peptides may help detect weaknesses in tumor cells

Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Curbing immune system infighting could make treatment more effective for pancreatic cancer

HMS study reveals key instigator of nerve cell damage in ALS patients

New study may offer vital clues to understanding how Zika virus affects the developing brain

Tel Aviv University researchers unravel how melanoma spreads to distant organs

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

Neuropathic pain could be significantly reduced by targeting brain cells

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

Scientists develop novel multifunctional platform to integrate imaging and photo-induced cancer therapy

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

Scientists identify mutation responsible for new, rare genetic disorder

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

Improve fermentation and cell culture performance with real-time gas analysis eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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