Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Kidney cancer survival rates: an interview with Dr Wong-Ho Chow

There are two major forms of kidney cancer. One is called renal cell cancer, which is an adenocarcinoma that occurs in the renal parenchyma. The other major type is called renal pelvis cancer, which is mostly of transitional cell type and they form in the centre of the kidney where the urine collects.

7 Dec 2012

Researchers discover 29 proteins associated with spread of kidney cancer

Researchers at St. Michael's hospital have identified 29 proteins that are likely to be involved in the spread of kidney cancer. The discovery will help physicians recognize which tumours are going to behave more aggressively and provide those patients with more intensive treatment and closer followup.

7 Dec 2012

Elderly cope better with oral cancer

Older individuals with oral squamous cell carcinoma report better health-related quality of life at one year after curative surgical treatment than do their younger counterparts, indicate UK study results.

6 Dec 2012

Infrared therapy could help prevent anal cancer in HIV-positive population

Infrared coagulopathy treatment of a potential precursor of anal cancer is effective and warrants further study as a way to reduce anal cancer incidence and mortality among HIV-infected people, report researchers.

30 Nov 2012

Study shows how cancer cells control ON/OFF switch of EMT program

A team of scientists, led by researchers at the University of California, San Diego School of Medicine, has shown for the first time how cancer cells control the ON/OFF switch of a program used by developing embryos to effectively metastasize in vivo, breaking free and spreading to other parts of the body, where they can proliferate and grow into secondary tumors.

30 Nov 2012

Novartis to highlight key data from extensive oncology portfolio at SABCS and ASH meeting

Novartis will highlight more than 140 presentations on key data from its extensive oncology portfolio at the leading year-end scientific meetings devoted to hematology and breast cancer, demonstrating continued innovation in research and development efforts to advance the care of patients with cancer and rare diseases.

30 Nov 2012

Exelixis announces FDA approval of COMETRIQ for treatment of medullary thyroid cancer

Exelixis, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved COMETRIQ (cabozantinib) for the treatment of progressive, metastatic medullary thyroid cancer (MTC).

30 Nov 2012

Breast cancer overdiagnosis concerns for USA

Around a third of screening-detected breast cancers in US women in 2008 may have been overdiagnosed, suggests research published in The New England Journal of Medicine.

26 Nov 2012

Tivantinib holds personalized therapy promise in HCC

Tivantinib is an effective second-line therapy for hepatocellular carcinoma patients whose tumors exhibit high MET receptor tyrosine kinase expression, indicate phase II study results.

26 Nov 2012

Researchers reveal molecular mechanisms that lead to basal cell carcinoma initiation

Advanced online publication in Nature Cell Biology: Researchers at the Université libre de Bruxelles, uncover the molecular mechanisms leading to basal cell carcinoma initiation.

26 Nov 2012

Perfusion of renal masses on MR corresponds to histopathologic diagnosis

A magnetic resonance imaging technique that uses blood as a contrast medium is able to distinguish between different histopathologic diagnoses of solid renal masses based on their perfusion level, claims a team of scientists.

22 Nov 2012

Tumors 'not always greatest mortality risk in RCC patients'

Patients with localized solid kidney tumors may be at greater risk for death from non-cancer-related causes before that from disease progression and cancer-related mortality, say US researchers who developed a comorbidity-based risk prediction model.

22 Nov 2012

Tumour burden predicts prognosis in mRCC

Tumor burden plays an independent prognostic and predictive role in metastatic renal cell carcinoma, a clinical trial shows.

22 Nov 2012

Temsirolimus effective for mRCC patients on hemodialysis

Research findings published in the International Journal of Clinical Oncology suggest that temsirolimus effectively stabilizes disease progression in patients with metastatic renal cell carcinoma undergoing hemodialysis.

22 Nov 2012

Factors influencing pain in head and neck cancer patients clarified

Individuals with head and neck cancer frequently report pain 1 year after diagnosis, despite being treated with analgesics, show US study results.

22 Nov 2012

Bevacizumab ruled out for stage III colorectal cancer

Findings from the AVANT trial do not support the use of bevacizumab in patients receiving oxaliplatin-based chemotherapy for resected stage III or high-risk stage II colon carcinoma.

19 Nov 2012

Cancer Network, ONCOLOGY present two part primer report on targeted therapies in solid tumors

UBM Medica US announces that Cancer Network and the journal ONCOLOGY are presenting a two part primer report on targeted therapies in solid tumors.

17 Nov 2012

Vitiligo patients have low risk for skin cancer

Evidence suggests that patients with vitiligo have a reduced risk for both melanoma and nonmelanoma skin cancer.

16 Nov 2012

Denosumab associated with improved overall survival in NSCLC patients

It is common for patients initially diagnosed with lung cancer to have the cancer spread to sites like the liver, brain and bone. One of the most frequent sites of metastases is the bone, with an estimated 30 to 40 percent of patients with non-small-cell lung cancer (NSCLC) developing bone loss.

16 Nov 2012

Gene therapy shows promise against dry mouth in cancer patients

Injecting an adenoviral vector encoding human aquaporin-1 into the parotid glands of head and neck cancer survivors improves their symptoms of dry mouth induced by radiation therapy, show study results.

15 Nov 2012