Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

NIH receives $10 million grant for research on breast cancer metastasis

The American Cancer Society predicts that 40,000 American women will die from breast cancer this year. Most of those deaths will occur due to cells from the primary tumor that spread to other parts of the body-the process known as metastasis.

20 Jun 2014

New model for HIV-1 infection offers promising option for clinical research

HIV-1, the virus responsible for most cases of AIDS, is a very selective virus. It does not readily infect species other than its usual hosts — humans and chimpanzees.

20 Jun 2014

New research reveals gene's role in type 1 diabetes

New research describes details of how a diabetes-related gene functions on a biological pathway that affects the release of insulin. The study authors say that finding drugs that act on that pathway may eventually lead to a new treatment for type 1 diabetes.

20 Jun 2014

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell's energy factory. They report their findings this week in Cell.

20 Jun 2014

Clinical trial shows that selumetinib drug can delay progression of metastatic uveal melanoma

For the first time, a therapy has been found that can delay progression of metastatic uveal melanoma, a rare and deadly form of melanoma of the eye.

20 Jun 2014

New treatment for ovarian cancer can improve response rates

Doctors at the University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center in Phoenix reported today in Lancet Oncology that a new treatment for ovarian cancer can improve response rates (increase the rate of tumor shrinkage) and prolong the time until cancers recur.

20 Jun 2014

Synaptic levels of protein clathrin are determinant factor for plasticity of neurons

Researchers of the group of cellular and molecular neurobiology of the Bellvitge Biomedical Research Institute (IDIBELL) and the University of Barcelona, led by researcher Artur Llobet, have shown that synaptic levels of the protein clathrin are a determinant factor for synaptic plasticity of neurons.

20 Jun 2014

Research provides unique insight into lncRNAs that regulate lung development

It's a long way from DNA to RNA to protein, and only about two percent of a person's genome is eventually converted into proteins.

19 Jun 2014

Researchers discover crucial process that regulates development of blood vessels

Biologists at The Scripps Research Institute (TSRI) have discovered a crucial process that regulates the development of blood vessels.

19 Jun 2014

Researchers find shared genetic link in autoimmune response among PV patients

Autoimmune disease occurs when the body's own natural defense system rebels against itself. One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds together skin cells.

19 Jun 2014

Detective work maps special gene variant among Greenlanders which plays role in type 2 diabetes

A spectacular piece of detective work has mapped a special gene variant among Greenlanders which plays a particularly important role in the development of type 2 diabetes.

19 Jun 2014

Study: Women who are overweight have faulty switch

Crucially, the discovery, published today in the journal Nature Communications, shows that women who are overweight have a faulty switch.

19 Jun 2014

Electroanalysis journal publishes a special issue about clinical diagnostics

The demand for the development of novel diagnostic tools with interest for clinical analysis is increasing.

19 Jun 2014

Electroanalysis journal publishes a special issue about clinical diagnostics

The demand for the development of novel diagnostic tools with interest for clinical analysis is increasing.

19 Jun 2014

New technology to control specific protein functions in living cells by using lights

Researchers at the Institute for Basic Science (IBS) in South Korea have succeeded in developing the world's first technology to control specific protein functions in living cells by using lights, which may be useful in future cancer cell research.

18 Jun 2014

U-M researchers detail new discoveries about basic biology of dystonia

Twist and hold your neck to the left. Now down, and over to the right, until it hurts. Now imagine your neck - or arms or legs - randomly doing that on their own, without you controlling it.

18 Jun 2014

New study on transmitophagy process may help treat diverse disorders

It's broadly assumed that cells degrade and recycle their own old or damaged organelles, but researchers at University of California, San Diego School of Medicine, The Johns Hopkins University School of Medicine and Kennedy Krieger Institute have discovered that some neurons transfer unwanted mitochondria - the tiny power plants inside cells - to supporting glial cells called astrocytes for disposal.

18 Jun 2014

Compound developed as cholesterol-fighting molecule can kill cancerous cells

Researchers at the University of Missouri have proven that a compound initially developed as a cholesterol-fighting molecule not only halts the progression of breast cancer, but also can kill the cancerous cells.

18 Jun 2014

Increase in protein helps store dopamine and protects from Parkinson's disease

Researchers from Emory's Rollins School of Public Health discovered that an increase in the protein that helps store dopamine, a critical brain chemical, led to enhanced dopamine neurotransmission and protection from a Parkinson's disease-related neurotoxin in mice.

18 Jun 2014

Scottsdale Healthcare, TGen initiate AG-120 clinical trial in patients with solid tumors

The Virginia G. Piper Cancer Center at Scottsdale Healthcare and the Translational Genomics Research Institute are studying the safety and effectiveness of a new drug, AG-120, for treatment of patients with solid tumors, especially those with brain tumors and gallbladder bile duct cancer.

18 Jun 2014