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Research shows probiotic B. longum KACC 91563 has ability to reduce effects of food allergies

Lactobacillus might sound familiar when the topic of probiotics comes up, but they are only one of many types of bacteria that have proven health benefits.

16 Mar 2016

Anti-anxiety drug reduces autistic features in Jacobsen syndrome mice

About half of children born with Jacobsen syndrome, a rare inherited disease, experience social and behavioral issues consistent with autism spectrum disorders. Researchers at University of California, San Diego School of Medicine and collaborators developed a mouse model of the disease that also exhibits autism-like social behaviors and used it to unravel the molecular mechanism that connects the genetic defects inherited in Jacobsen syndrome to effects on brain function.

16 Mar 2016

Scientists find evidence that amyloid fibrils adopt several distinct architectures in human, animal tissues

Formation of amyloid fibrils is a characteristic feature of neurogenerative diseases like Alzheimer's. As published in the journal Angewandte Chemie, German and American scientists have found evidence that these fibrils adopt several distinct three-dimensional architectures in real patient and animal tissues.

16 Mar 2016

Cell-based tests reveal no activity in cells exposed to vapour from Vype ePen

A series of cell-based tests developed to compare the biological impact of cigarette smoke with e-cigarette vapour revealed no activity in cells exposed to vapour from Vype ePen, a commercially available e-cigarette.

16 Mar 2016

MicroRNA can help combat obesity and diabetes

Obesity, which is associated with low-grade inflammation, is an important contributor in the development of diabetes and cardiovascular disease. While the role of several organs including adipose tissue have been implicated in this process, the cell types and factors driving this process have not been clear.

16 Mar 2016

Blocking Mena protein could help prevent cancer metastasis, says MIT researcher

A new study from MIT reveals how cancer cells take some of their first steps away from their original tumor sites. This spread, known as metastasis, is responsible for 90 percent of cancer deaths.

16 Mar 2016

ROBO1 protein may delay progression of breast cancer

A protein called ROBO1 may delay the progression of breast cancer, according to a paper published in The Journal of Cell Biology. The study, "Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness" by Lily Thao-Nhi Le and colleagues, identifies a signaling pathway that may protect breast cells from the tumorigenic effects of stiff extracellular matrices.

16 Mar 2016

Experimental drug improves survival rate of majority of lung cancer patients compared to standard chemotherapy

In global clinical trials, patients with advanced metastatic lung cancer who were treated with a targeted immunotherapy drug lived significantly longer and with fewer side effects than those who received standard second-line chemotherapy, according to a new Kaiser Permanente study published today in the journal The Lancet.

15 Mar 2016

Bruker showcases innovative NMR solutions for pharmaceutical industry at ENC 2015

At the 56th Experimental Nuclear Magnetic Resonance Conference, Bruker this week is show-casing several innovative drug discovery, drug development and process control solutions for small molecule NMR characterization in the pharmaceutical industry.

From Bruker BioSpin Group 15 Mar 2016

Study could lead to potential new therapeutic target with fewer side effects for hypertension

A team of Vermont investigators has been issued a patent for their discovery of a molecule that rescues damaged blood vessels, yet preserves healthy vessels and could serve as a springboard for a new pharmaceutical therapy with fewer side effects for hypertension - a major risk factor for cardiovascular and kidney disease that effects roughly one in three people in the U.S.

15 Mar 2016

St. Jude scientists develop insights to guide development of powerful novel anti-influenza drugs

By analyzing the molecular details of how artificially created drug-resistant flu strains manage to survive treatment, St. Jude Children's Research Hospital scientists have developed insights to guide development of powerful new anti-influenza drugs. These compounds will target a viral enzyme critical to the virus' proliferation in the body.

15 Mar 2016

UCSF study marks important step toward finding cure for Ebola

In experiments carried out partly at the Department of Energy's SLAC National Accelerator Laboratory, scientists have determined in atomic detail how a potential drug molecule fits into and blocks a channel in cell membranes that Ebola and related "filoviruses" need to infect victims' cells.

15 Mar 2016

Prognostic test could help lower cancer recurrence for colorectal patients

Colorectal cancer, one of the most commonly diagnosed cancers in the United States, is not a commonly discussed disease. Often symptomless in early stages, the cancer is more difficult to treat as it progresses, requiring chemotherapy in later stages. Researchers at the University of Notre Dame are working on a way to identify patients who would benefit from chemotherapy before the cancer progresses.

15 Mar 2016

New drug shows promise against mesothelioma

A new drug is showing promise as a treatment for mesothelioma - one of the most lethal cancers of all.

15 Mar 2016

Heart failure drug has unexpected ability to block herpesvirus infection

Today, there is only one class of antiviral medicines against herpesviruses - a family of viruses that cause mononucleosis, herpes, and shingles, among other illnesses - meaning options for treating these infections are limited. If viruses become resistant to these frontline treatments, a growing problem particularly in clinical settings, there are no alternative drugs to serve as backup.

15 Mar 2016

Researchers identify new mutation responsible for spinocerebellar ataxia

Using the genetic information of two different families with three generations of disease, researchers have identified a new mutation responsible for a degenerative and ultimately fatal movement disorder. Through induced pluripotent stem cell techniques, researchers also grew neurons from one patient in the laboratory to be used in future experiments.

15 Mar 2016

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

The ability to reprogram cells has revolutionized stem cell research with major implications for almost all fields of modern biology. A decade ago Shinya Yamanaka described a procedure that revolutionized stem cell biology. Using a genetic trick that introduces a cocktail of four genes into cultured cells from human biopsies, he was able to generate induced pluripotent stem cells (iPS) from mature skin or blood cells

15 Mar 2016

Protein C News and Research

Research shows probiotic B. longum KACC 91563 has ability to reduce effects of food allergies

Anti-anxiety drug reduces autistic features in Jacobsen syndrome mice

Scientists find evidence that amyloid fibrils adopt several distinct architectures in human, animal tissues

Cell-based tests reveal no activity in cells exposed to vapour from Vype ePen

MicroRNA can help combat obesity and diabetes

Blocking Mena protein could help prevent cancer metastasis, says MIT researcher

ROBO1 protein may delay progression of breast cancer

Experimental drug improves survival rate of majority of lung cancer patients compared to standard chemotherapy

Bruker showcases innovative NMR solutions for pharmaceutical industry at ENC 2015

Study could lead to potential new therapeutic target with fewer side effects for hypertension

St. Jude scientists develop insights to guide development of powerful novel anti-influenza drugs

UCSF study marks important step toward finding cure for Ebola

Prognostic test could help lower cancer recurrence for colorectal patients

New drug shows promise against mesothelioma

Heart failure drug has unexpected ability to block herpesvirus infection

Researchers identify new mutation responsible for spinocerebellar ataxia

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Anticancer drug restores hearing in neurofibromatosis patients

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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