Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

York researchers move closer to finding new treatments for chronic bladder diseases

Using human cells, they have mapped how different proteins bind along the DNA to control which genes are active during barrier formation.

14 Mar 2017

Defect in non-coding DNA could give rise to language impairments in children

The human genome is made up of ~3 billion letters of DNA and at each position it is possible to have different letters, called variants. Some variants are harmless but others can be detrimental, making it a mammoth task to find out which variants cause a disorder.

14 Mar 2017

New research project unravels disease mechanisms of schizophrenia

Researchers at Karolinska Institutet collaborating in the large-scale Karolinska Schizophrenia Project are taking an integrative approach to unravel the disease mechanisms of schizophrenia.

14 Mar 2017

New technique opens door for biochemists to create better therapeutic antibodies

Antibodies are the foot soldiers of our immune system. These specialized, Y-shaped proteins attach to bacteria and viruses, where they either block the pathogen's activity directly, or signal the immune system's cells to destroy the invader.

14 Mar 2017

Researchers discover cellular defects that underlie familial form of Parkinson's disease

Howard Hughes Medical Institute researchers have introduced a genetic mutation found in some patients with early onset Parkinson's disease into mice, creating a new animal model of the disease.

14 Mar 2017

Beneficial bacteria may be key to reverse gut inflammation seen in inflammatory bowel diseases

Beneficial bacteria may be the key to helping to reverse a cycle of gut inflammation seen in certain inflammatory bowel diseases, University of North Carolina Lineberger Comprehensive Cancer Center researchers have found.

13 Mar 2017

Swansea University experts assess contribution of ultra-rare genetic variation in common epilepsies

Despite progress in understanding the genetics of rare childhood epilepsies, the common adult forms of epilepsy have proven less amenable to traditional gene-discovery analyses.

13 Mar 2017

Researchers produce images that predate formation of beta-amyloid plaques in Alzheimer’s disease

Researchers at Lund University in Sweden have used the MAX IV synchrotron in Lund - the strongest of its kind in the world - to produce images that predate the formation of toxic clumps of beta-amyloid, the protein believed to be at the root of Alzheimer's disease.

13 Mar 2017

Evolution of immuno-oncology

Immuno-oncology did not exist four years ago, it's a term coined by Dr. Axel Hoos, Head of the newly defined immuno-oncology department at GSK. He is also Senior Vice President Therapeutic Area (TA) and Head for Oncology R&D. Previously, it was referred to as cancer immunotherapy, but now it is called immuno-oncology (IO).

13 Mar 2017

Targeting cancer stem cells may be effective way to prevent spread of squamous cell carcinoma

Targeting cancer stem cells may be a more effective way to overcome cancer resistance and prevent the spread of squamous cell carcinoma — the most common head and neck cancer and the second-most common skin cancer, according to a new study by cancer researchers at the UCLA School of Dentistry.

10 Mar 2017

Endostatin can decrease proliferation of castration-resistant prostate cancer cells

Failure of hormone deprivation therapy, which is used to slow prostate cancer in patients, leads to castration-resistant prostate cancer, a lethal form of advanced disease with limited treatment options.

10 Mar 2017

Mayo Clinic study: High-intensity aerobic exercise can reverse cellular aspects of aging

Everyone knows that exercise is good for you, but what type of training helps most, especially when you're older -- say over 65? A Mayo Clinic study says it's high-intensity aerobic exercise, which can reverse some cellular aspects of aging. The findings appear in Cell Metabolism.

10 Mar 2017

Investigational RSV vaccine protects cattle from respiratory diseases

A novel vaccine developed by scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, protected cattle from respiratory syncytial virus (RSV) infection, according to research published online in npj Vaccines on March 8.

10 Mar 2017

Protein News and Research

Further Reading

York researchers move closer to finding new treatments for chronic bladder diseases

Defect in non-coding DNA could give rise to language impairments in children

New research project unravels disease mechanisms of schizophrenia

New technique opens door for biochemists to create better therapeutic antibodies

Researchers discover cellular defects that underlie familial form of Parkinson's disease

Beneficial bacteria may be key to reverse gut inflammation seen in inflammatory bowel diseases

Swansea University experts assess contribution of ultra-rare genetic variation in common epilepsies

Researchers produce images that predate formation of beta-amyloid plaques in Alzheimer’s disease

Evolution of immuno-oncology

Targeting cancer stem cells may be effective way to prevent spread of squamous cell carcinoma

Endostatin can decrease proliferation of castration-resistant prostate cancer cells

Mayo Clinic study: High-intensity aerobic exercise can reverse cellular aspects of aging

Investigational RSV vaccine protects cattle from respiratory diseases

Researchers discover intestinal quiescent stem cells that are resistant to chemotherapy

Discovery of link between RNA quality control and longevity may shed light on mechanisms behind aging

New clinical study to test promising diabetes drug in people with MND

Stony Brook researchers discover novel metabolic pathway of lipid ceramide involved in cell death

Researchers complete design phase for fully synthetic yeast genome

Researchers identify new gene that can lead to sudden death among young people

Study identifies therapeutic target for diabetic retinopathy

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