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New approach for easier detection of SARS-CoV-2 via swabs and saliva

A recent Israeli study points toward Reverse Transcription Loop-Mediated Isothermal Amplification (RT-LAMP) as a potentially effective tool for acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on-the-spot detection by using swabs or saliva – addressing the community need for simple surveillance.

28 Apr 2020

Rat spinal cords control muscular behaviors in novel biohybrid robots

Biological robots, or biobots, draw inspiration from natural systems to mimic the motions of organisms, such as swimming or jumping.

28 Apr 2020

Father's Toxoplasma infection can impact their offspring's brain health and behavior

Australian researchers have revealed for the first time that males infected with the Toxoplasma parasite can impact their offspring's brain health and behavior.

28 Apr 2020

Immune-regulating drug reverses dental problems in aging mice

A drug that has life-extending effects on mice also reverses age-related dental problems in the animals, according to a new study published today in eLife.

28 Apr 2020

CNIC researchers develop mouse model to examine the mechanical function of proteins

The Molecular Mechanics of the Cardiovascular System group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Jorge Alegre Cebollada, in partnership with an international scientific team, has generated the first experimental mouse model that allows direct analysis of the mechanical function of proteins in living organisms.

28 Apr 2020

New Leica platform adds an additional dimension of information to confocal imaging

Leica Microsystems, has announced the launch of its flagship new confocal microscopy platform, called STELLARIS.

From Leica Microsystems GmbH 28 Apr 2020

Disarmed anthrax toxin tested as a way to combat Covid-19

Disarmed anthrax toxin is being tested as a way of fighting the Covid-19 virus.

28 Apr 2020

Testing the Structural Studies Of Biopolymers with the CPMAS Cryoprobe

In this interview, Program Manager, Alia Hassan and Application Scientist Barbara Perrone, discuss the game-changing sensitivity enhancements achieved with the CPMAS CryoProbe – all the benefits of the CryoProbe, now available for solids.

From Bruker BioSpin Group 28 Apr 2020

Researchers describe an underlying biological basis for mylagic encephalomyelitis/chronic fatigue syndrome

Mylagic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling and complex illness. Affected persons often cannot pursue ordinary activities -- physical or mental -- because of an incapacitating loss of energy and other symptoms, and may find themselves confined to bed or house-bound for years.

28 Apr 2020

Researchers discover a new mode of protein degradation by ubiquitin-proteasome system

The proteasome is a major proteolytic machine that regulates cellular proteostasis through selective degradation of ubiquitylated proteins.

28 Apr 2020

Research on SARS-CoV-2 spike protein may lead to new vaccines and treatments

The virus that causes COVID-19 is studded on its exterior with "spike proteins," a key component in its ability to infect human cells. Two University of Georgia researchers, Rob Woods and Parastoo Azadi, are investigating the proteins and sugars on the surface of the virus with the goal of finding information that could lead to vaccines and therapeutics.

28 Apr 2020

International collaborators propose a new ranking scheme to classify SARS-CoV-2

In November of 2019--likely, even earlier--a tiny entity measuring just a few hundred billionths of a meter in diameter began to tear apart human society on a global scale.

28 Apr 2020

GRAIL to present new data at the American Association for Cancer Research (AACR) annual meeting

GRAIL, Inc., a healthcare company whose mission is to detect cancer early, today announced that new data for its investigational multi-cancer early detection blood test will be presented at the American Association for Cancer Research (AACR) Virtual Annual Meeting I.

From GRAIL, Inc. 28 Apr 2020

A new tool for developing gene therapies against cancer, genetic disorders, and blood diseases

A UCLA-led research team today reports that it has developed a new method for delivering DNA into stem cells and immune cells safely, rapidly and economically.

28 Apr 2020

Study marks a major step towards beta cell replacement therapy

The loss of insulin-secreting beta cells by autoimmune destruction leads to type 1 diabetes. Clinical islet cell transplantation has the potential to cure diabetes, but donor pancreases are rare.

28 Apr 2020

Antibiotic exposure and its priming effect on disease-causing bacteria

Antibiotics save lives -- but using them also helps antibiotic-resistant strains evolve and spread. Each year, antibiotic-resistant bacteria infect some 2.8 million people in the United States, killing more than 35,000, according to the Centers for Disease Control and Prevention.

27 Apr 2020

Using neutralising antibodies in the fight against COVID-19

While many scientists and pharmaceutical companies are racing to develop a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, there is also an urgent need for a coronavirus disease (COVID-19) treatment. The potent virus has now spread to 210 countries and territories, affecting more than 3.04 million people. Now, a team of German scientists is working on using antibodies to prevent and treat COVID-19.

27 Apr 2020

Spaceflight causes key changes in cultured heart cells

Spaceflight changes much about the human body, including how the heart functions and how cells that create heart tissue behave. Scientists studying these changes on the International Space Station continue to report important discoveries.

27 Apr 2020

The approved dose of ivermectin alone not useful in treating COVID-19

A new paper published on the preprint server medRxiv in April 2020 shows that the use of the already approved drug ivermectin in clinical trials to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)s not feasible. This contradicts earlier reports of its ability to suppress the virus in vitro.

27 Apr 2020

Prolonged corticosteroid treatment increases adrenal gland inflammation

New research by academics at the University of Bristol has found evidence that prolonged treatment of synthetic corticosteroid drugs increases adrenal gland inflammation in response to bacterial infection, an effect that in the long-term can damage adrenal function.

27 Apr 2020