Protein C News and Research

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CMV-based vaccine provides protection against Ebola virus

As the latest in a series of studies, researchers at Plymouth University, National Institutes of Health and University of California, Riverside, have shown the ability of a vaccine vector based on a common herpesvirus called cytomegalovirus (CMV) expressing Ebola virus glycoprotein (GP), to provide protection against Ebola virus in the experimental rhesus macaque, non-human primate (NHP) model.

16 Feb 2016

Variations in Tie2 gene play significant role in patient responses to infections

Major infections such as influenza and bacterial sepsis kill millions of people each year, often resulting fro dangerous complications that impair the body's blood vessels. But the reasons why some patients experience these dramatic responses to infections -- and others don't -- have been unclear.

16 Feb 2016

New UAB research shows association between verapamil use and lower glucose levels in diabetics

A new University of Alabama at Birmingham research paper published in the journal Diabetes Research and Clinical Practice shows for the first time that there is an association of verapamil use and lower fasting glucose levels in humans with diabetes.

15 Feb 2016

Scientists discover role of nucleocytoplasmic transport in specific forms of ALS and FTD

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating adult-onset neurodegenerative disorders.

15 Feb 2016

Mayo Clinic researchers uncover clues to apraxia of speech

It may start with a simple word you can't pronounce. Your tongue and lips stumble, and gibberish comes out. Misspeaking might draw a chuckle from family and friends. But, then, it keeps happening. Progressively, more and more speech is lost. Some patients eventually become mute from primary progressive apraxia of speech, a disorder related to degenerative neurologic disease.

15 Feb 2016

Scientists modify plants' defense system to confer resistance to virus

Scientists at Indiana University have modified a plant gene that normally fights bacterial infection to confer resistance to a virus.

15 Feb 2016

Research: Breakfast can make obese people more active

Eating breakfast causes obese people to be more active, according to the latest research published from researchers at the University of Bath (UK).

15 Feb 2016

New experimental method could help detect Lyme disease at the earliest time of infection

When it comes to early diagnosis of Lyme disease, the insidious tick-borne illness that afflicts about 300,000 Americans annually, finding the proverbial needle in the haystack might be a far easier challenge--until now, perhaps. An experimental method developed by federal and university researchers appears capable of detecting the stealthy culprit Lyme bacteria at the earliest time of infection, when currently available tests are often still negative.

15 Feb 2016

Anti-cancer drug delays onset of Alzheimer's disease

Researchers have identified a drug that targets the first step in the toxic chain reaction leading to the death of brain cells, suggesting that treatments could be developed to protect against Alzheimer's disease, in a similar way to how statins are able to reduce the risk of developing heart disease.

15 Feb 2016

New approach could be used to treat Duchenne muscular dystrophy

Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and Center for Duchenne Muscular Dystrophy at UCLA have developed a new approach that could eventually be used to treat Duchenne muscular dystrophy.

14 Feb 2016

Protein Sciences, UNIGEN agree to supply Flublok influenza vaccine for the U.S. market from Japan

Protein Sciences Corporation (Meriden, CT and Pearl River, NY) and UMN Pharma Inc. (Akita, Akita prefecture, Japan) announced today that Protein Sciences and UNIGEN Inc., a joint venture of UMN and IHI Corporation (Koto-ku, Tokyo, Japan), entered into an agreement to source bulk Flublok influenza vaccine from Japan for the U.S. market.

12 Feb 2016

TSRI scientists receive $1.7 million NIH grant to find new target for treating Huntington's disease

Scientists from the Florida campus of The Scripps Research Institute have won nearly $1.7 million from the National Institutes of Health's National Institute of Neurological Disorders and Stroke to investigate the mechanisms that contribute to Huntington's disease, a fatal inherited disease that some have described as having ALS, Parkinson's and Alzheimer's--at the same time.

12 Feb 2016

Transition from milk-based diet to family food impacts Infants’ gut bacteria

It is the transition to eating the family's food and not the weight of the mother that has the greatest impact on the composition of gut bacteria in nine-month-old children.

12 Feb 2016

Tick genome study sheds light on occurrences of Lyme disease

After a decade-long research effort the genome of the deer tick has been sequenced by an international team of scientists, including researchers from the SIB Swiss Institute of Bioinformatics.

12 Feb 2016

Apellis Pharmaceuticals completes $47.1M Series D preferred stock financing

Apellis Pharmaceuticals, Inc., today announced that it has completed a $47.1 million Series D preferred stock financing, co-led by new investors Cormorant Asset Management, Hillhouse Capital Group and venBio Global Strategic Fund, joining existing investors Morningside Venture Investments, AJU IB Investment, and Epidarex Capital.

12 Feb 2016

Interplay between gene variant and socio-economic environment may determine girls' food choices

If you're fat, can you blame it on your genes? The answer is a qualified yes. Maybe. Under certain circumstances. Researchers are moving towards a better understanding of some of the roots of obesity.

12 Feb 2016

Pioneering technique shows promise for new medical diagnostics, targeted drug delivery

Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules--the enzymes.

12 Feb 2016

CNIO researchers reveal how combination of dasatinib and demcizumab reduces lung adenocarcinomas

Lung cancer is one of the most prevalent types of cancer, with more than 20,000 new cases diagnosed each year in Spain. Lung adenocarcinomas carrying oncogenic KRAS, the engine driving these tumours in 30% of cases, constitute the most aggressive sub-type because, unlike other types of lung cancer, there are no targeted therapies beyond the standard cisplatin-based treatment.

12 Feb 2016

Transition to family foods drives development of infant gut microbiota

After the age of nine months, the development of the infant gut microbiota is driven by the transition to family foods, not maternal obesity, according to results from a new study. The study was published online this week in mSphere, an open-access journal of the American Society for Microbiology.

11 Feb 2016

TAU research highlights neuroprotective potential of protein-protectant drug candidate SKIP

Activity-dependent neuroprotective protein (ADNP), essential for brain formation, is frequently mutated in children on the autism spectrum. In older men and women, ADNP expression in the blood is correlated with cognition and further altered in Alzheimer's disease.

11 Feb 2016

Protein C News and Research

CMV-based vaccine provides protection against Ebola virus

Variations in Tie2 gene play significant role in patient responses to infections

New UAB research shows association between verapamil use and lower glucose levels in diabetics

Scientists discover role of nucleocytoplasmic transport in specific forms of ALS and FTD

Mayo Clinic researchers uncover clues to apraxia of speech

Scientists modify plants' defense system to confer resistance to virus

Research: Breakfast can make obese people more active

New experimental method could help detect Lyme disease at the earliest time of infection

Anti-cancer drug delays onset of Alzheimer's disease

New approach could be used to treat Duchenne muscular dystrophy

Protein Sciences, UNIGEN agree to supply Flublok influenza vaccine for the U.S. market from Japan

TSRI scientists receive $1.7 million NIH grant to find new target for treating Huntington's disease

Transition from milk-based diet to family food impacts Infants’ gut bacteria

Tick genome study sheds light on occurrences of Lyme disease

Apellis Pharmaceuticals completes $47.1M Series D preferred stock financing

Interplay between gene variant and socio-economic environment may determine girls' food choices

Pioneering technique shows promise for new medical diagnostics, targeted drug delivery

CNIO researchers reveal how combination of dasatinib and demcizumab reduces lung adenocarcinomas

Transition to family foods drives development of infant gut microbiota

TAU research highlights neuroprotective potential of protein-protectant drug candidate SKIP

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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