Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Melanoma patients' immunotherapy response linked to diversity and makeup of gut bacteria

Melanoma patients' response to a major form of immunotherapy is associated with the diversity and makeup of trillions of potential allies and enemies found in the digestive tract, researchers at The University of Texas MD Anderson Cancer Center report at the ASCO-Society for Immunotherapy in Cancer meeting in Orlando.

22 Feb 2017

Scientists unravel novel protein catalysts that can direct biosynthesis of hapalindole-type alkaloids

Alkaloids are natural nitrogen-containing compounds produced by plants and microbes. These molecules, such as morphine and quinine, are important human medicines.

22 Feb 2017

New approach to generate high volume of hair cells may help restore full hearing

The loss of tiny, sound-sensing cells in the inner ear, known as "hair cells," is a leading cause of hearing loss, a public health problem affecting at least 5 percent of the world population.

22 Feb 2017

Research on repair of broken hearts hints at possibility of new designer cardiovascular therapies

Unlike the self-repair abilities of our skin, bone and other tissues, which can readily heal and rebuild themselves after injury, evolution has left the mammalian heart with relatively little regenerative capacity.

22 Feb 2017

Gene expression patterns could help predict treatment for breast cancer, research shows

A Michigan State University breast cancer researcher has shown that effective treatment options can be predicted based on the way certain breast cancer genes act or express themselves.

21 Feb 2017

Danish research may pave way for immunological treatment of cancer

Researchers from Aarhus University have found an important piece of the puzzle leading towards an understanding of how our innate immune system reacts against viral infections and recognises foreign DNA, for example from dying cancer cells.

21 Feb 2017

Research may show new ways to repress inflammation at outset

Researchers at the University of Tübingen, working with colleagues in other parts of Germany and in the United States, have identified an enzyme as a kind of biological gauge regulating inflammation in the human body.

21 Feb 2017

Pitt researchers uncover genetic marker that may predict drug response in many cancer types

Researchers at the University of Pittsburgh School of Medicine have uncovered a novel genetic mechanism of thyroid cancer, as well as a marker that may predict response to a particular class of drugs, not just in patients with thyroid cancer, but in those with many other types of cancer as well.

21 Feb 2017

Scientists engineer smallest CRISPR-Cas9 system to date

Scientists at the Center for Genome Engineering, within the Institute for Basic Science0, in collaboration with KIM Eunji and KIM Jeong Hun have engineered the smallest CRISPR-Cas9 to date, delivered it to the muscle cells and in the eyes of mice via adeno-associated viruses and used it to modify a gene causing blindness.

21 Feb 2017

EPFL scientists develop new computer model for better design of allosteric drugs

EPFL scientists have created a new computer model that can help better design of allosteric drugs, which control proteins "at a distance".

21 Feb 2017

Cancer cells adapt nerve cell mechanisms to fuel aggressive tumor growth and spread

How we think and fall in love are controlled by lightning-fast electrochemical signals across synapses, the dynamic spaces between nerve cells. Until now, nobody knew that cancer cells can repurpose tools of neuronal communication to fuel aggressive tumor growth and spread.

21 Feb 2017

microDimensions launches new version of high precision whole slide alignment software

microDimensions launches a new version of its high precision whole slide alignment software Slidematch. With the new version users can align digital whole slide images from consecutive sections in brightfield and fluorescence mode, e.g. for the evaluation of the HER2 status of cancer patients.

From microDimensions - Bramlage Scientific GmbH 21 Feb 2017

Study opens way for targeted local treatments for patchy skin disorders

With the aid of thousands of skin biopsies and over a hundred kilograms of skin, researchers at Karolinska Institutet have observed how two subgroups of immune cell behave in healthy skin.

20 Feb 2017

Penn researchers find new way to track rare T cells in blood after annual flu vaccine

For most vaccines to work the body needs two cell types - B cells and T helper cells - to make antibodies. B cells are the antibody factories and the T helper cells refine the strength and accuracy of antibodies to home and attack their targets.

20 Feb 2017

Disappointing Merck drug news provides new blueprint for moving towards cure for Alzheimer's

The recent announcement that Merck is halting a Phase II/III study for a promising Alzheimer's treatment (verubecestat) was another setback in the continued and intensive effort to deliver an innovative therapy by 2020.

17 Feb 2017

New approach could make organometallic catalysis applicable for therapy or diagnostics

A gold catalyst can be delivered to a target organ in a higher organism where it performs a chemical transformation visualized by bioimaging.

17 Feb 2017

Targeting tumor suppressor protein could be effective treatment for some AML patients, study suggests

Researchers in Germany have discovered that a tumor suppressor protein thought to prevent acute myeloid leukemia (AML) can actually promote a particularly deadly form of the disease.

17 Feb 2017

Research provides more evidence that mRNA vaccines can protect mice against Zika virus

Vaccine developers have successfully protected mice against Zika by injecting synthetic messenger RNA that encodes for virus proteins into the animals.

17 Feb 2017

New study confirms role of PAK4 protein in growth, spread of pancreatic cancer cells

A new study that confirms the role of a protein called PAK4 in the movement and growth of pancreatic cancer cells could help researchers find new ways to tackle the disease.

17 Feb 2017

Lower vitamin D levels increase risk of clinical relapse in Ulcerative Colitis patients, study finds

A new study led by researchers at Beth Israel Deaconess Medical Center has found that lower levels of vitamin D in the blood increase the risk of clinical relapse in patients with Ulcerative Colitis, an inflammatory bowel disease that causes long-lasting inflammation and ulcers in the colon.

17 Feb 2017

Protein News and Research

Further Reading

Melanoma patients' immunotherapy response linked to diversity and makeup of gut bacteria

Scientists unravel novel protein catalysts that can direct biosynthesis of hapalindole-type alkaloids

New approach to generate high volume of hair cells may help restore full hearing

Research on repair of broken hearts hints at possibility of new designer cardiovascular therapies

Gene expression patterns could help predict treatment for breast cancer, research shows

Danish research may pave way for immunological treatment of cancer

Research may show new ways to repress inflammation at outset

Pitt researchers uncover genetic marker that may predict drug response in many cancer types

Scientists engineer smallest CRISPR-Cas9 system to date

EPFL scientists develop new computer model for better design of allosteric drugs

Cancer cells adapt nerve cell mechanisms to fuel aggressive tumor growth and spread

microDimensions launches new version of high precision whole slide alignment software

Study opens way for targeted local treatments for patchy skin disorders

Penn researchers find new way to track rare T cells in blood after annual flu vaccine

Disappointing Merck drug news provides new blueprint for moving towards cure for Alzheimer's

New approach could make organometallic catalysis applicable for therapy or diagnostics

Targeting tumor suppressor protein could be effective treatment for some AML patients, study suggests

Research provides more evidence that mRNA vaccines can protect mice against Zika virus

New study confirms role of PAK4 protein in growth, spread of pancreatic cancer cells

Lower vitamin D levels increase risk of clinical relapse in Ulcerative Colitis patients, study finds

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