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A mathematical solution for precise control of cellular “noise”

Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the answer appears to lie not in genetic differences, but in biological noise - random fluctuations in molecular activity that occur even among genetically identical cells.

2 Jan 2026

Elevated bacteria levels in tumors weaken immune response, studies show

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

2 Jan 2026

New therapeutic approach converts immune cells inside tumors into anticancer cell therapies

Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable to perform their roles properly due to suppression by the tumor.

2 Jan 2026

Newly identified rare genetic variant reduces the risk of leukemia

A newly identified and rare genetic variant slows the growth of mutated blood stem cells, researchers report, and it reduces the risk of leukemia.

2 Jan 2026

First human 'lung-on-chip' model developed using stem cells from a single donor

Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.

2 Jan 2026

Study uncovers how aggressive breast cancer cells escape immune defenses

With a new study in the journal Science Bulletin, researchers at Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University have discovered a new way that aggressive breast cancer cells escape the immune defenses.

1 Jan 2026

Soft wireless bioelectronic implant targets the splenic nerve to reduce inflammation

For millions suffering from chronic inflammatory diseases like inflammatory bowel disease (IBD), managing flare-ups often involves powerful drugs with significant side effects.

1 Jan 2026

Label-free polarized light reveals subtle red blood cell deformations

Red blood cells are essential for oxygen transport and immune function in the human body. When these cells become abnormally shaped, they can indicate serious health conditions, including diabetes, malaria, hereditary blood disorders, and vascular diseases.

1 Jan 2026

Novel method can generate functional organoids from human adult adipose tissue

A recent study published in Engineering has unveiled a novel approach to generating functional organoids from human adult adipose tissue.

30 Dec 2025

New computational method reconstructs how cells decide their fate

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics of how cells decide their fate.

30 Dec 2025

Silica nanomatrix enhances immunotherapy for solid tumors

Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of all disease-related deaths in the city in 2025. While chemotherapy remains a major treatment modality, its side effects and the risk of relapse challenges for patients.

30 Dec 2025

Dihydrotanshinone I induces autophagic cell death in ovarian cancer

A recent study published in Engineering has shed light on the potential therapeutic effects of dihydrotanshinone I (DHT), a compound derived from the traditional Chinese herb Salvia miltiorrhiza, on ovarian cancer.

30 Dec 2025

Euphorbia neriifolia L. extract protects against cardiomyocyte injury and heart failure

Announcing a new publication for Acta Materia Medica journal. Heart failure (HF) remains a major global health challenge with limited therapeutic options, thus prompting the search for novel cardioprotective agents among traditional Chinese medicines.

30 Dec 2025

New insights into the global expansion of Candida auris

The fungal species Candida auris is spreading across the globe, and gaining in virulence, according to a new review by a Hackensack Meridian Center for Discovery and Innovation (CDI) scientist and colleagues.

30 Dec 2025

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

Diabetic kidney disease affects a growing proportion of people with diabetes and remains the leading cause of end-stage renal disease.

30 Dec 2025

Immune cell energy metabolism shapes the progression of atherosclerosis

Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, drives the progression of atherosclerosis - and how this knowledge could lead to better diagnostics and future therapies.

30 Dec 2025

Advancing stem cell regeneration through animal-free culture systems

Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection.

30 Dec 2025

Epigenetic plasticity in germinal center B cells may help explain lymphoma origins

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible, or plastic, stem-cell-like state in the lymph nodes, according to a new preclinical study from Weill Cornell Medicine investigators.

30 Dec 2025

Inflammation and immune suppression fuel aggressive SCLC behavior and spread

Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only five percent. Despite this poor prognosis, SCLC is initially highly responsive to chemotherapy.

30 Dec 2025

Combination therapy offers hope for AML patients facing drug resistance

A research team at Oregon Health & Science University has discovered a promising new drug combination that may help people with acute myeloid leukemia overcome resistance to one of the most common frontline therapies.

30 Dec 2025