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New peptide antibiotic stops bacteria by binding where no drug has before

Researchers discovered lariocidin, a lasso peptide antibiotic that kills multidrug-resistant bacteria by binding a novel ribosomal site.

27 Mar 2025

Study uncovers surprising role for calcium in shaping life's earliest molecular structures

A new study led by researchers at the Earth-Life Science Institute (ELSI) at Institute of Science Tokyo has uncovered a surprising role for calcium in shaping life's earliest molecular structures.

27 Mar 2025

Negative stiffness in calf muscles enhances high-speed hopping

Researchers at the University of Tokyo reveal the way our legs adapt to fast movements. When people hop at high speeds, key muscle fibers in the calf shorten rather than lengthen as forces increase, which they call "negative stiffness." This counterintuitive process helps the leg become stiffer, allowing for faster motion. The findings could improve training, rehabilitation, and even the design of prosthetic limbs or robotic exoskeletons.

27 Mar 2025

Cedars-Sinai study shows rapid healing of heart damage with cell therapy

A scientific technique that rapidly increases the body's production of anti-inflammatory cells promoted healing from heart attacks in mice, according to a new study by investigators from the Smidt Heart Institute at Cedars-Sinai. Once adapted to treat humans, the technique could potentially be used to repair heart muscle damage after a heart attack and be applied to a variety of inflammatory disorders.

26 Mar 2025

Report shows alarming measles resurgence in Europe and US

A recent report shows cases of measles across the World Health Organization's European Region, which includes the UK, are the highest they've been for more than 25 years. At the same time, large outbreaks of measles in the US have led to the first measles deaths there since 2015.

26 Mar 2025

Genetic and environmental factors in schizophrenia

Schizophrenia affects millions worldwide, yet its causes remain one of the greatest medical mysteries. In an exclusive Genomic Press Interview, Dr. Consuelo Walss-Bass, a pioneering researcher in psychiatric genetics, shares how both genetic predisposition and environmental factors contribute to severe mental health disorders.

26 Mar 2025

Breakthrough DNA delivery system could revolutionize chronic disease treatment

A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer.

25 Mar 2025

CDC study identifies leading culprits of foodborne illness

Researchers from the CDC and Colorado School of Public Health estimate that seven major pathogens caused 9.9 million foodborne illnesses in the US in 2019. Norovirus led illness and hospitalization counts, while Salmonella caused the most deaths.

25 Mar 2025

New trial aims to make rectal cancer more responsive to radiation

City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, has opened a phase 1 trial seeking to one day transform rectal cancer from a mostly radiation-resistant disease to one that can be cured using radiation and chemotherapy.

25 Mar 2025

ELRIG announces Prof Rory Johnson and Dr Shalini Andersson as keynote speakers at Therapeutic Oligonucleotides 2025

ELRIG, a not-for-profit, volunteer-led organization for the drug discovery community, today announced the keynote speakers for Therapeutic Oligonucleotides 2025 taking place at the AstraZeneca R&D site in Gothenburg, Sweden from 14-15 May. Prof Rory Johnson, Associate Professor, University College Dublin, and Dr Shalini Andersson, Vice President Nucleic Acid Therapeutics, AstraZeneca will lead this year's event focused on 'drugging the undruggable'.

25 Mar 2025

Sperm viability boosted in IVF with glycan technology

The success of in vitro fertilization depends on many factors, one of which is sperm viability. A recent study from the University of Illinois Urbana-Champaign documents a new way to select viable sperm and prolong their viability in the laboratory, reducing one source of variability during the process.

24 Mar 2025

Researchers develop TIM-3 decoy to enhance CAR-T therapy effectiveness for B-ALL tumors

B-cell Acute Lymphoblastic Leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases, but it can affect people of any age.

24 Mar 2025

Smell-based test taken at home could predict cognitive impairment in older adults

When it comes to early detection of cognitive impairment, a new study suggests that the nose knows. Researchers from Mass General Brigham developed olfactory tests-in which participants sniff odor labels that have been placed on a card-to assess people's ability to discriminate, identify and remember odors.

24 Mar 2025

UZH researchers develop decoy molecules to restore immune defense

An immune system defect makes affected individuals vulnerable to severe viral diseases such as influenza or COVID-19. It is caused by the body's own antibodies, which inhibit important defense proteins known as type I interferons.

24 Mar 2025

The Colorado psychedelic mushroom experiment has arrived

Colorado regulators are issuing licenses for providing psychedelic mushrooms and are planning to authorize the state's first "healing centers," where the mushrooms can be ingested under supervision, in late spring or early summer.

24 Mar 2025

CDC confirms black-legged ticks can cause red meat allergy in humans

Researchers confirmed that black-legged ticks (Ixodes scapularis) can trigger alpha-gal syndrome in humans. A 10-year surveillance in Maine identified 23 confirmed cases of the meat allergy outside the lone star tick’s known range.

23 Mar 2025

Researchers trace 73% of US Salmonella cases to chicken and vegetables

Researchers used genome sequencing and machine learning to trace the top food sources behind Salmonella infections in the US. Chicken and vegetables emerged as the primary culprits, together accounting for up to 73% of human cases with known sources.

23 Mar 2025

Asgard archaea provide clues to the origin of complex life forms

Ten years ago, nobody knew that Asgard archaea even existed. In 2015, however, researchers examining deep-sea sediments discovered gene fragments that indicated a new and previously undiscovered form of microbes.

22 Mar 2025

Groundbreaking study unveils key mechanism for neuronal identity regulation

A team of researchers from the Institute for Neurosciences, a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, in collaboration with researchers from Columbia University (New York, USA), has identified a mechanism that regulates the production of two different proteins from the same gene.

22 Mar 2025