Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Missing gene may cause kidney and urinary tract defects in people with DiGeorge syndrome

Loss of function of the CRKL gene causes kidney and urinary tract defects in people with DiGeorge syndrome, a multinational team of scientists led by Columbia University Medical Center has found.

25 Jan 2017

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Under ordinary circumstances, the protein tau contributes to the normal, healthy functioning of brain neurons. In some people, though, it collects into toxic tangles that damage brain cells.

25 Jan 2017

Scientists define working mechanism of promising anti-cancer molecules

An international team of scientists, including MIPT researchers, has defined the way their promising anti-cancer molecules work.

25 Jan 2017

Researchers design antibody that recognizes and destroys blood cancer stem cells

A protein-sugar molecule, CD99, occurs more frequently than normal on stem cells responsible for blood cancers, including acute myeloid leukemia (AML) and the related myelodysplastic syndromes.

25 Jan 2017

HCI scientists uncover new way that bones get destroyed through breast cancer

Once breast cancer spreads through the body, it can degrade a patient's healthy bones, causing numerous problems. Scientists at Huntsman Cancer Institute at the University of Utah have identified a new way that bones get destroyed through cancer.

25 Jan 2017

Scientists discover new way to inhibit growth of glioblastoma

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O'Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

25 Jan 2017

UI biologists discover protein that appears to regulate chromosome movement

Before an egg becomes fertilized, sets of chromosomes must pair up to pass along genetic information. This happens within each reproductive cell, where separate chromosomes of male and female origin move toward each other and eventually join.

25 Jan 2017

TUM researchers decipher secret behind cohesion of heart muscles

Our hearts beat a life long. With every beat our heart muscle contracts and expands. How this can work throughout an entire life remains largely a mystery. Researchers at the Technical University of Munich have now measured the forces acting between the building blocks titin and α-actinin which stabilize the muscle.

25 Jan 2017

Scientists discover cause of tumour resistance to angiogenesis inhibitors

A new study conducted by MedUni Vienna in collaboration with scientists from Hungary and Sweden has now shown for the first time that the success of specialised drugs to inhibit blood supply to tumours - so-called angiogenesis inhibitors - is compromised by the fact that these drugs do not effectively penetrate the tumour tissue and so do not reach the smallest blood vessels in the tumour.

25 Jan 2017

Scientists uncover new way to starve tumor cells to death

For decades, scientists have tried to halt cancer by blocking nutrients from reaching tumor cells, in essence starving tumor cells of the fuel needed to grow and proliferate. Such attempts often have disappointed because cancer cells are nimble, relying on numerous backup routes to continue growing.

24 Jan 2017

TSRI scientists receive $1.8 million grant to develop drug candidates for multiple diseases

Scientists from the Florida campus of The Scripps Research Institute have been awarded approximately $1.8 million from the National Institute of General Medical Sciences of the National Institutes of Health to develop a series of drug candidates for a number of diseases, including heart disease, rheumatoid arthritis and several neurodegenerative disorders.

24 Jan 2017

New drugs that target neighbour proteins may help halt cancer progression

Cancer is caused by an accumulation of genetic changes in a cell, that overcome the normal checks and balances leading to uncontrolled growth. A complex, interacting network of proteins controls all of a cell's processes, from metabolism to growth and division.

24 Jan 2017

Adelaide researchers find new driver for breast density linked to cancer risk

Adelaide researchers are one step closer to breast cancer prevention after finding a new driver for breast density, an identified risk factor for breast cancer.

24 Jan 2017

Penn researchers unravel missing steps involved in movement of cellular cargo

Every time a hormone is released from a cell, every time a neurotransmitter leaps across a synapse to relay a message from one neuron to another, the cell must undergo exocytosis.

24 Jan 2017

Researchers reveal central role of new key players in meiosis

Where would we be without meiosis and recombination? For a start, none of us sexually reproducing organisms would be here, because that's how sperm and eggs are made. And when meiosis doesn't work properly, it can lead to infertility, miscarriage, birth defects and developmental disorders.

24 Jan 2017

Chemists show that synthetic nanoparticles can achieve structural complexity of biomolecules

Chemists at Carnegie Mellon University have demonstrated that synthetic nanoparticles can achieve the same level of structural complexity, hierarchy and accuracy as their natural counterparts - biomolecules.

24 Jan 2017

Study provides insights into molecular mechanisms of ZIKV infection

Zika virus (ZIKV) interferes with the cellular machinery controlling cell division and alters the expression of hundreds of genes guiding the formation and development of neurons and astrocytes, according to findings released on January 23rd 2017 at Scientific Reports.

24 Jan 2017

Tiny 'submarines' could help treat stomach diseases with acid-sensitive drugs

Tiny “submarines” that speed independently through the stomach, use gastric acid for fuel (while rapidly neutralizing it), and release their cargo precisely at the desired pH: Though it may sound like science fiction, this is a new method for treating stomach diseases with acid-sensitive drugs introduced by scientists in the journal Angewandte Chemie.

24 Jan 2017

Better dietary resilience and nutrition can promote healthy aging, review finds

Improving dietary resilience and better integration of nutrition in the health care system can promote healthy aging and may significantly reduce the financial and societal burden of the "silver tsunami."

24 Jan 2017

DeNovix launches DS-C Cuvette Spectrophotometer for rapid, accurate UV-Vis analysis

DeNovix Inc., a developer and manufacturer of life science instrumentation for bio-research announces the launch of the DS-C Cuvette Spectrophotometer.

From DeNovix Inc. 24 Jan 2017