Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Novel discovery could lead to new therapy to combat obesity, diabetes

By manipulating a biochemical process that underlies cells' energy-burning abilities, investigators at Beth Israel Deaconess Medical Center have made a novel discovery that could lead to a new therapy to combat obesity and diabetes.

10 Apr 2014

University of Montreal scientists discover molecular details of kissing disease virus attacks

University of Montreal researchers have discovered how a component of the Epstein Barr (EBV) virus takes over our cells gene regulating machinery, allowing the virus to replicate itself.

10 Apr 2014

Rice University research targets Parkinson's, Huntington's and other proteasomal diseases

Synthetic genetic circuitry created by researchers at Rice University is helping them see, for the first time, how to regulate cell mechanisms that degrade the misfolded proteins implicated in Parkinson's, Huntington's and other diseases.

9 Apr 2014

Scientists to develop handheld testing device to provide same day diagnosis from patient's bedside

Scientists at the University of Southampton are aiming to develop a handheld testing device to provide same day diagnosis from a patient's bedside.

9 Apr 2014

Research opens new possibilities for blocking runaway cell division in cancer

The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis -- opening new possibilities for throwing a wrench in the machine and blocking runaway cell division in cancer.

9 Apr 2014

Research shows blocking DNA repair improves radiation therapy for glioblastomas

UT Southwestern Medical Center researchers have demonstrated in both cancer cell lines and in mice that blocking critical DNA repair mechanisms could improve the effectiveness of radiation therapy for highly fatal brain tumors called glioblastomas.

9 Apr 2014

New lab at the Nencki Institute conducts research on neurodegenerative diseases

The Laboratory of Preclinical Studies of Higher Standard, the newest lab of the Neurobiology Center at the Nencki Institute in Warsaw, Poland, will conduct basic research aimed to explain molecular mechanisms responsible for neurodegenerative diseases.

9 Apr 2014

Researcher wins 2014 Abraham White Distinguished Science Award for contributions in treatment of neurological diseases

Michael Chopp, Ph.D., scientific director of the Henry Ford Neuroscience Institute at Henry Ford Hospital, won the 2014 Abraham White Distinguished Science Award for his discovery of the role of a protein in the treatment of brain injuries and neurodegenerative diseases.

9 Apr 2014

Herpes simplex viral therapy in conjunction with radiation proves effective in treating malignant gliomas

Researchers at the University of Alabama at Birmingham report a genetically engineered herpes simplex viral therapy is safe when used in conjunction with radiation in the treatment of malignant gliomas, one of the most deadly forms of brain cancer.

9 Apr 2014

Study shows critical role of immune system in protecting against viruses and cancer cells

A team of researchers at the IRCM, led by Andr- Veillette, MD, explains how our immune system kills abnormal blood cells. Their discovery, recently published in the Journal of Experimental Medicine, could eventually lead to new treatment avenues for leukemia, lymphoma and certain types of infectious viral diseases.

9 Apr 2014

Study provides insights into why alcohol has negative effect on wound healing

People who are injured while binge drinking are much slower to heal from wounds suffered in car accidents, shootings, fires, etc.

9 Apr 2014

Researchers find new molecular targets for aggressive brain tumor

Researchers from the Geisel School of Medicine at Dartmouth will present a scientific poster on Tuesday, April 8, 2014 at the American Association of Cancer Researchers conference in San Diego, CA. The research identifies a potential characteristic for predicting outcome in a deadly form of brain cancer known as glioblastoma multiforme.

9 Apr 2014

Researchers demonstrate advantages of HOPE fixation strategy

They discovered that the so-called HOPE method allows tissue samples to be treated such that they do not only meet the requirements of clinical histology, but can still be characterised later on by modern methods of proteomics, a technique analysing all proteins at once.

9 Apr 2014

Scientists uncover surprising link between brain development and gene tied to breast cancer

Scientists at the Salk Institute have uncovered details into a surprising-and crucial-link between brain development and a gene whose mutation is tied to breast and ovarian cancer.

9 Apr 2014

Study shows subpopulations of breast cancer cells cooperate to aid tumor growth

Subpopulations of breast cancer cells sometimes cooperate to aid tumor growth, according to Penn State College of Medicine researchers, who believe that understanding the relationship between cancer subpopulations could lead to new targets for cancer treatment.

9 Apr 2014

Production of Immutep’s ImmuFact IMP321 starts at WuXi AppTec facilities in China

Immutep S.A., the biopharmaceutical company specializing in immuno-oncology, and Eddingpharm have started production of Immutep’s ImmuFact IMP321 (a LAG-3Ig fusion protein) at WuXi AppTec facilities in China. The product is being produced to European, U.S. and Chinese GMP standards.

8 Apr 2014

Janssen submits supplemental New Drug Application for IMBRUVICA to the U.S. FDA

Janssen Research & Development, LLC ("Janssen") today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA™ (ibrutinib) to the U.S. Food and Drug Administration (FDA) by its collaboration partner Pharmacyclics, Inc.

8 Apr 2014

Study: VISTA deficiency leads to enhanced immune activation

Researchers at the Geisel School of Medicine at Dartmouth have found that the body's immune system response was enhanced when they disrupted VISTA, a protein that prevents the immune system from overreacting.

8 Apr 2014

PeptiDream develops novel macrocyclic peptide inhibitor for treatment of multiple influenza strains

PeptiDream Inc., a public Tokyo-based biopharmaceutical company ("PeptiDream")( TOKYO:4587) announced today, in collaboration with The Tokyo Metropolitan Institute of Medical Science ("Tokyo Metropolitan Institute") the discovery and development of a novel macrocyclic peptide inhibitor for the treatment of multiple influenza strains.

8 Apr 2014

Research to understand exactly how bleach kills bacteria

Spring cleaning often involves chlorine bleach, which has been used as a disinfectant for hundreds of years. But our bodies have been using bleach's active component, hypochlorous acid, to help clean house for millennia. As part of our natural response to infection, certain types of immune cells produce hypochlorous acid to help kill invading microbes, including bacteria.

8 Apr 2014

Protein News and Research

Further Reading

Novel discovery could lead to new therapy to combat obesity, diabetes

University of Montreal scientists discover molecular details of kissing disease virus attacks

Rice University research targets Parkinson's, Huntington's and other proteasomal diseases

Scientists to develop handheld testing device to provide same day diagnosis from patient's bedside

Research opens new possibilities for blocking runaway cell division in cancer

Research shows blocking DNA repair improves radiation therapy for glioblastomas

New lab at the Nencki Institute conducts research on neurodegenerative diseases

Researcher wins 2014 Abraham White Distinguished Science Award for contributions in treatment of neurological diseases

Herpes simplex viral therapy in conjunction with radiation proves effective in treating malignant gliomas

Study shows critical role of immune system in protecting against viruses and cancer cells

Study provides insights into why alcohol has negative effect on wound healing

Researchers find new molecular targets for aggressive brain tumor

Researchers demonstrate advantages of HOPE fixation strategy

Scientists uncover surprising link between brain development and gene tied to breast cancer

Study shows subpopulations of breast cancer cells cooperate to aid tumor growth

Production of Immutep’s ImmuFact IMP321 starts at WuXi AppTec facilities in China

Janssen submits supplemental New Drug Application for IMBRUVICA to the U.S. FDA

Study: VISTA deficiency leads to enhanced immune activation

PeptiDream develops novel macrocyclic peptide inhibitor for treatment of multiple influenza strains

Research to understand exactly how bleach kills bacteria

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