Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

Adaptimmune today announced that it has been awarded a grant of £2.1 million from the Biomedical Catalyst Fund, managed by the UK’s innovation agency the Technology Strategy Board and the Medical Research Council. The prestigious award will expedite the development of Adaptimmune’s second engineered T cell therapy programme into the clinic in triple negative breast cancer.

26 Mar 2014

HIV and Hepatitis C vaccines now closer to reality

Plans for a new type of DNA vaccine to protect against the deadly HIV and Hepatitis C viruses have taken an important step forward, with University of Adelaide researchers applying for a patent based on groundbreaking new research.

26 Mar 2014

SLU researchers awarded NIH grants to search for a drug to cure hepatitis B

Two grants from the National Institutes of Health will allow Saint Louis University researchers to build on breakthroughs in understanding the hepatitis B virus and begin the search for a drug to cure - not just halt - the illness.

26 Mar 2014

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute, recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died.

26 Mar 2014

TG2 protein is a key mediator in Porphyromonas gingivalis infection, study finds

Scientists at Forsyth, along with a colleague from Northwestern University, have discovered that the protein, Transgultaminase 2 (TG2), is a key component in the process of gum disease. TG2 is widely distributed inside and outside of human cells. The scientists found that blocking some associations of TG2 prevents the bacteria Porphyromonas gingivalis (PG) from adhering to cells. This insight may one day help lead to novel therapies to prevent gum disease caused by PG.

26 Mar 2014

MIT biological engineers trying to adapt MRI to visualize gene activity inside the brains of living animals

Doctors commonly use magnetic resonance imaging (MRI) to diagnose tumors, damage from stroke, and many other medical conditions. Neuroscientists also rely on it as a research tool for identifying parts of the brain that carry out different cognitive functions.

26 Mar 2014

Renal Ventures Management publishes first cookbook of kidney friendly recipes for renal patients

In recognition of Kidney Health Awareness Month, Renal Ventures Management, LLC (RVM), a leading provider of dialysis services for patients suffering from chronic kidney failure, has published its first cookbook of kidney friendly recipes for it renal patients and their families.

25 Mar 2014

Endogenous tissue growth: an interview with Laurent Grandidier, CEO, Xeltis

ETG or Endogenous Tissue Growth is a new therapeutic category in which surgeons use implants designed to allow the body to repair itself by spontaneously growing natural, healthy tissue from the inside without the use of stem cells or animal-derived products.

25 Mar 2014

The Center for Applied Nanotechnology presents a ready-to-use reagent for the detection of poly-histidine tagged proteins in Blot assays

The nano-experts from the Center for Applied Nanotechnology (CAN) GmbH expand their product portfolio by CANdots® Series G - His Detect, which is a ready-to-use reagent for the detection of poly-histidine tagged proteins in Blot assays. It is easy to handle, highly sensitive as well as time saving compared to standard methods available on the market, e.g. ECL.

25 Mar 2014

Researchers receive grants to advance work in prevention of premature birth

Researchers at UT Southwestern Medical Center received grants totaling $600,000 from the March of Dimes Foundation to advance their work in the prevention of premature birth, which affects about one out of nine babies born annually in the U.S. and is the leading cause of newborn death.

25 Mar 2014

Researchers develop mathematical model that provides insights about molecular mechanisms behind virus assembly

Mathematicians at the University of York have joined forces with experimentalists at the University of Leeds to take an important step in discovering how viruses make new copies of themselves during an infection.

25 Mar 2014

Researchers discover novel population of neutrophils that exhibit enhanced microbial killing activity

Case Western Reserve University researchers have discovered a novel population of neutrophils, which are the body's infection control workhorses. These cells have an enhanced microbial killing ability and are thereby better able to control infection.

25 Mar 2014

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

A protein known to promote cancer appears to give the blood vessels strength and shape, researchers report. When yes-associated protein, or YAP, is deleted from vascular smooth muscle cells during development, the protein makes thin-walled blood vessels that over-dilate in response to the usual pressure of blood flow, said Dr. Jiliang Zhou, vascular biologist at the Medical College of Georgia at Georgia Regents University.

25 Mar 2014

Researchers develop one-step analysis for detecting tumor markers in blood

Benign growth, or cancer? Tumor markers in the blood help determine whether the patient is afflicted with a malign tumor and whether it is excreting markers more vigorously - involving highly specific proteins. An increased concentration in the blood provides one indication of the disease for physicians. However, it has been quite expensive in time and effort to detect the markers thus far. This is because all kinds of molecules and proteins are teeming in the blood. To be able to detect a single specific one, doctors must first separate and purify the blood in several steps, and then isolate the marker they are searching for from the rest of the molecules.

25 Mar 2014

NeuroVive Pharmaceutical initiates research collaboration with A1M Pharma

NeuroVive Pharmaceutical AB (publ) and A1M Pharma AB (publ) have announced that the two companies are initiating a research collaboration in mitochondrial medicine. The partnership is governed by a collaboration agreement signed on 21 March 2014.

25 Mar 2014

Agios initiates AG-120 Phase 1 study to evaluate advanced solid tumors with IDH1 mutation

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and inborn errors of metabolism, today announced dose administration for the first patient in a Phase 1 study of AG-120 in patients with advanced solid tumors with an isocitrate dehydrogenase-1 (IDH1) mutation.

25 Mar 2014

Protein News and Research

Further Reading

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

HIV and Hepatitis C vaccines now closer to reality

SLU researchers awarded NIH grants to search for a drug to cure hepatitis B

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

TG2 protein is a key mediator in Porphyromonas gingivalis infection, study finds

MIT biological engineers trying to adapt MRI to visualize gene activity inside the brains of living animals

Renal Ventures Management publishes first cookbook of kidney friendly recipes for renal patients

Endogenous tissue growth: an interview with Laurent Grandidier, CEO, Xeltis

The Center for Applied Nanotechnology presents a ready-to-use reagent for the detection of poly-histidine tagged proteins in Blot assays

Researchers receive grants to advance work in prevention of premature birth

Researchers develop mathematical model that provides insights about molecular mechanisms behind virus assembly

Researchers discover novel population of neutrophils that exhibit enhanced microbial killing activity

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

Researchers develop one-step analysis for detecting tumor markers in blood

NeuroVive Pharmaceutical initiates research collaboration with A1M Pharma

Agios initiates AG-120 Phase 1 study to evaluate advanced solid tumors with IDH1 mutation

New technology gives tool to examine membrane proteins in natural environment of human cell

Low dose injections of artificial properdin provide protection against septic diseases

New research reveals new complexity to nerve cells in brain that could affect future therapies

Study uncovers one way that p53 acts to prevent cancer cell invasion

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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