Myocardial Infarction News and Research

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GlaxoSmithKline response to JAMA article on ICES retrospective analysis

The following is GlaxoSmithKline's response to the retrospective analysis by the Institute for Clinical Evaluative Sciences (ICES) titled "Thiazolidinediones and Cardiovascular Outcomes in Older Patients with Diabetes".

13 Dec 2007

New studies on brain and behavior from the world's leading scientists

The 2007 American College of Neuropsychopharmacology Annual Meeting will feature hundreds of new studies on brain and behavior from the world's leading scientists.

10 Dec 2007

Depression nearly triples the risk of death following a heart attack

...even when accounting for other heart attack risk factors, according to research presented at the American College of Neuropsychopharmacology (ACNP) annual meeting, which showed that among 360 depressed, post myocardial infarction patients followed for more than six years, those who did not recover from their depression in the first six months were more than twice as likely to die.

10 Dec 2007

Approval of Diovan (valsartan) in U.S. for hypertension in children and adolescents

Diovan (valsartan), an angiotensin receptor blocker or ARB, has been approved following a priority review by the U.S. Food and Drug Administration (FDA) for the treatment of high blood pressure in children and adolescents ages six to 16.

4 Dec 2007

Certain infusion therapy after heart attack does not appear to be beneficial, may cause harm

Infusion of a combination therapy consisting of glucose, insulin, and potassium, which was thought could be a beneficial treatment immediately following a heart attack, may increase the risk of heart failure and death in the first 3 days for patients with ST-segment elevation myocardial infarction (STEMI; a certain pattern on an electrocardiogram following a heart attack), according to a study in the November 28 issue of JAMA: The Journal of the American Medical Association.

27 Nov 2007

Non-smokers the big winners when it comes to smoking bans

American scientists have found that heart attacks decreased after a smoking ban was imposed but this only applied to non-smokers.

22 Nov 2007

People with no risk factors for heart disease can still experience heart attacks

An Indiana University study found that after a countywide smoking ban was implemented, hospital admissions for such heart attacks dropped 70 percent for non-smokers -- but not for smokers.

19 Nov 2007

GlaxoSmithKline implements changes to the US product label for Avandia

GlaxoSmithKline announced today that it is implementing changes to the US product label for Avandia(R) (rosiglitazone maleate), based on an extensive and thorough review by the FDA of myocardial ischemia data on Avandia, the most widely studied oral anti-diabetic medicine available.

15 Nov 2007

FDA adds warning for heart attacks to type 2 diabetes drug Avandia

The U.S. Food and Drug Administration announced today that the manufacturer of Avandia (rosiglitazone), a drug used to treat type 2 diabetes, has agreed to add new information to the existing boxed warning in the drug's labeling about potential increased risk for heart attacks.

14 Nov 2007

Nitrite/nitrate-rich foods may help in heart attack survival

Nitrite/nitrate found in vegetables, cured meats and drinking water may help you survive a heart attack and recover quicker, according to a pre-clinical study led by a cardiovascular physiologist at The University of Texas Health Science Center at Houston.

13 Nov 2007

Discovery of new hemoglobin function

A team of researchers from Wake Forest University, the National Institutes of Health and other institutions has discovered a previously undetected chemical process within the oxygen-carrying molecule hemoglobin that could have far-reaching implications for the treatment of cardiovascular diseases.

6 Nov 2007

Getting to hospital quickly once heart attack symptoms appear provides best chance of receiving right treatment

If you go to the hospital within one to two hours of the onset of symptoms of a heart attack, your chances of getting proper treatment are nearly 70 percent greater than those who wait 11 to 12 hours before seeking treatment, according to results presented at the American Heart Association's Scientific Sessions 2007 in Orlando, Fla.

6 Nov 2007

New risk factor for heart attack patients identified

6 Nov 2007

Living kidney donors show no increase in their risk of heart attacks

Living kidney donors show no increase in their risk of heart attacks or other cardiovascular events in the years after donation, according to the largest-ever study of the issue, being presented at the American Society of Nephrology's 40th Annual Meeting and Scientific Exposition in San Francisco.

5 Nov 2007

Anticoagulant bivalirudin following angioplasty in heart attack patients reduces adverse events and bleeding

Late-breaking data presented at TCT 2007, the scientific symposium of the Cardiovascular Research Foundation (CRF), show that the use of the anticoagulant bivalirudin following angioplasty in heart attack patients reduces net adverse clinical events by 24 percent compared to the standard treatment, and significantly reduces major bleeding that occurs after angioplasty by 40 percent.

24 Oct 2007

Coronary heart disease and women

Women who eat a healthy diet, drink moderate amounts of alcohol, are physically active, maintain a healthy weight and do not smoke have a significantly reduced risk of heart attack, according to a report in the October 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

22 Oct 2007

Whole grain breakfast cereals may reduce risk of heart failure in men

Men who consume a higher amount of whole grain breakfast cereals may have a reduced risk of heart failure, according to a report in the October 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

22 Oct 2007

Landmark stent trial to be presented at TCT 2007

The Cardiovascular Research Foundation (CRF) will release results of its landmark research study, HORIZONS AMI (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction) at the nineteenth annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium in Washington, D.C.

16 Oct 2007

Depression among patients with coronary artery disease

Depression has long had a popular link to cardiovascular disease and death. However, only during the last 15 years scientific evidence supporting this common wisdom has been available (Glassman et al., 2007a).

16 Oct 2007

Heart disease of the left main coronary artery is often an inherited condition that clusters in families

Moreover, they discovered that initially healthy siblings of a person with the condition were 2.5 times more likely to go on to develop some form of heart disease than were siblings of a patient with heart disease that did not relate to the left main coronary artery.

4 Oct 2007