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Gene regulation rather than genes make us unique

Once the human genome was sequenced in 2001, the hunt was on for the genes that make each of us unique. But scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and Yale and Stanford Universities in the USA, have found that we differ from each other mainly because of differences not in our genes, but in how they're regulated - turned on or off, for instance.

18 Mar 2010

Forensic high-tech assistant Virtobot used to perform virtual autopsies

Virtobot is the name of the forensic high-tech helpmate used at the University of Bern's Institute of Forensic Medicine to perform virtual autopsies. Developed as part of the National Centre of Competence in Research, Co-Me the industrial robot provides forensic doctors with a high precision, three-dimensional image of cadavers.

18 Mar 2010

New combination drug treatment for parasitic intestinal roundworms shows promise

Several drugs currently in use or in development control parasitic worms in the same way. That concerns health workers In developing countries where reinfestations often require repeated treatments. If worms develop resistance to one drug, the other treatments would likely fail as well.

18 Mar 2010

Berkeley HeartLab adopts GenTegra DNA to support diagnostic genetic testing for cardiovascular disease

GenVault Corporation today announced that Berkeley HeartLab, a subsidiary of Celera Corporation, has adopted GenTegra DNA to preserve and store diagnostic samples for genetic testing related to the management of cardiovascular disease.

18 Mar 2010

NIST and HHS to develop software tools to support health IT testing infrastructure

Fully incorporating modern information technology into the healthcare system promises many benefits, including better quality care, less paperwork and fewer medical errors while reducing unnecessary costs. In any such critical application, however, it's important to ensure that the new technology behaves as expected.

18 Mar 2010

Toxins released by certain microalgae can contaminate seafood and become toxic to humans

Toxins released by certain microalgae can contaminate fish and shellfish which then become toxic to humans. Researchers from CNRS and CEA have, for the first time, identified the mechanisms of action of two of these toxins.

18 Mar 2010

PPD, Southern Research Institute collaborate in pandemic and seasonal influenza vaccine research

PPD and Southern Research Institute today announced they have formed a collaborative agreement in pandemic and seasonal influenza vaccine research and development to provide clients a full spectrum of influenza vaccine development services by collaborating on client bids and projects.

18 Mar 2010

Alzheimer's disease: Gene expression level influences promotion of disorder or protection against development

Using sophisticated techniques that scan the genomes of patients, researchers at the Mayo Clinic campus in Florida have found that a gene appears to either help protect against development of Alzheimer's disease, or promote the disorder depending on the level of gene in the brain.

18 Mar 2010

Enzo Biochem announces supply and distribution agreement between Enzo Life Sciences and Cancer Genetics

Enzo Biochem, Inc., a vertically integrated biotechnology company engaged in the research, development, manufacture, licensing and marketing of innovative health care products, platforms and services based on molecular and cellular technologies, announced today a supply and distribution agreement between Enzo Life Sciences and privately-owned Cancer Genetics Inc., a leading producer of nucleic acid products used in genomic research.

18 Mar 2010

HDC, SPM enter into development and licensing agreements with Quest Diagnostics

Health Discovery Corporation and Smart Personalized Medicine, LLC announced today that they have entered into development and related licensing agreements with Quest Diagnostics Incorporated, the world’s leading provider of diagnostic testing, information and services.

From Quest Diagnostics 17 Mar 2010

Protalix BioTherapeutics commences clinical trial of human acetylcholinesterase for biodefense indications

Protalix BioTherapeutics, Inc. announced today that it has initiated a phase I clinical trial of PRX-105, the Company's plant cell expressed pegylated recombinant human acetylcholinesterase product candidate in development for biodefense indications. The trial is designed to study the safety of PRX-105 by administering a bolus intravenous injection of PRX-105 in healthy volunteers.

17 Mar 2010

Genetic test helps reduce hospitalization rates for heart patients on warfarin

Hospitalization rates for heart patients taking warfarin, the world's most-prescribed blood thinner, dropped by approximately 30 percent when genetic information was available to doctors prescribing the drug, researchers from Medco Health Solutions, Inc.-- in association with the Medco Research Institute™ -- and Mayo Clinic announced today.

17 Mar 2010

Low-income patients with brain tumors are less likely to be referred to specialty hospitals

African-American, Hispanic, and economically disadvantaged patients with brain tumors are significantly less likely to be referred to high-volume hospitals that specialize in neurosurgery than other patients of similar age, the same gender, and with similar comorbidities, according to new research by Johns Hopkins doctors.

17 Mar 2010

Researchers identify a novel way to study species-specific reproductive behavior

Researchers at the California Institute of Technology (Caltech) and the University of California, San Diego (UCSD) have discovered that injecting a simple hormone into leeches creates a novel way to study how hormones and the nervous system work together to produce species-specific reproductive behavior.

17 Mar 2010

Pathway Genomics' personal Genetic Health Report now available

Pathway Genomics Inc., a U.S. based genetic testing company, announced the immediate availability of its personal Genetic Health Report. This customized and innovative personal genetic health report contains information on more than 70 health conditions, including pharmacogenetics (prescription medication response), propensity for complex disease, and carrier status (pre-pregnancy health).

17 Mar 2010

Delphi Screener devices help detect HPV in women

More cases of human papillomavirus (HPV) infection - the major cause of cervical cancer - could be detected if home-testing kits were given to women who cannot attend conventional cervical screening, a Dutch study has found.

17 Mar 2010

Celerus Diagnostics to present Wave RPD totally automated HC staining system at annual USCAP meeting

Celerus Diagnostics will introduce a totally automated immunohistochemistry (IHC) staining system, the much-anticipated Wave RPD, at the United States and Canadian Association of Pathologists (USCAP) annual meeting being held in Washington DC, March 22–24. The new system is the first of its kind, capable of delivering totally automated IHC results in one hour.

17 Mar 2010

Key cellular defect in protein synthesis can lead to cancer susceptibility

UCSF researchers have discovered that a key cellular defect that disturbs the production of proteins in human cells can lead to cancer susceptibility. The scientists also found that a new generation of inhibitory drugs offers promise in correcting this defect.

17 Mar 2010

Tolerx publishes follow-up data from study of otelixizumab therapy for new onset T1DM patients

Tolerx, Inc., today announced the publication in Diabetologia, the journal of the European Association for the Study of Diabetes, of the four-year follow-up clinical data from new onset type 1 diabetes (T1DM) patients (age 12-39) who received a single short course of therapy with otelixizumab (ChAglyCD3).

16 Mar 2010

Blocking RhoA enzyme increases survival in SMA mouse model

Scientists from the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa have identified a promising new approach for developing drugs to treat Spinal muscular atrophy (SMA), the leading inherited cause of death in infants and toddlers. Dr. Rashmi Kothary and his doctoral student Melissa Bowerman have found that an enzyme called RhoA is overly active in a mouse model of the disease and blocking this enzyme can greatly increase survival. The study is published in Human Molecular Genetics.

16 Mar 2010

Laboratory News and Research

Gene regulation rather than genes make us unique

Forensic high-tech assistant Virtobot used to perform virtual autopsies

New combination drug treatment for parasitic intestinal roundworms shows promise

Berkeley HeartLab adopts GenTegra DNA to support diagnostic genetic testing for cardiovascular disease

NIST and HHS to develop software tools to support health IT testing infrastructure

Toxins released by certain microalgae can contaminate seafood and become toxic to humans

PPD, Southern Research Institute collaborate in pandemic and seasonal influenza vaccine research

Alzheimer's disease: Gene expression level influences promotion of disorder or protection against development

Enzo Biochem announces supply and distribution agreement between Enzo Life Sciences and Cancer Genetics

HDC, SPM enter into development and licensing agreements with Quest Diagnostics

Protalix BioTherapeutics commences clinical trial of human acetylcholinesterase for biodefense indications

Genetic test helps reduce hospitalization rates for heart patients on warfarin

Low-income patients with brain tumors are less likely to be referred to specialty hospitals

Researchers identify a novel way to study species-specific reproductive behavior

Pathway Genomics' personal Genetic Health Report now available

Delphi Screener devices help detect HPV in women

Celerus Diagnostics to present Wave RPD totally automated HC staining system at annual USCAP meeting

Key cellular defect in protein synthesis can lead to cancer susceptibility

Tolerx publishes follow-up data from study of otelixizumab therapy for new onset T1DM patients

Blocking RhoA enzyme increases survival in SMA mouse model

Lab Diagnostics and Automation - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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