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Atherosclerotic plaques spread downstream in coronary arteries

In human coronary arteries, atherosclerotic plaques tend to spread downstream because of the changes in blood flow patterns the plaque causes, researchers have found.

16 Nov 2011

Sex during adolescence can have negative effects on body and mood well into adulthood

A new study suggests that sex during adolescence can have lasting negative effects on the body and mood well into adulthood, most likely because the activity occurs when the nervous system is still developing.

16 Nov 2011

Researchers discover human genes that might contribute to ALS

Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, is a universally fatal neurodegenerative disease. Mutations in two related proteins, TDP-43 and FUS, cause some forms of ALS. Specifically, these two proteins are RNA-binding proteins that connect to RNA to regulate the translation of proteins and other cellular functions such as RNA splicing and editing. In a new study, researchers at the Perelman School of Medicine at the University of Pennsylvania discovered additional human genes with properties similar to TDP-43 and FUS that might also contribute to ALS.

16 Nov 2011

Advaxis licenses ISG15 tumor antigen from University of Pennsylvania

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, has exclusively licensed the use of antigen ISG15 in Advaxis' Lm-LLO based immunotherapies from the University of Pennsylvania.

16 Nov 2011

Researchers to begin drug development projects for rare and neglected diseases

Researchers will begin drug development projects for rare and neglected diseases that include potential treatments for a musculoskeletal disorder, a cognitive dysfunction disorder, a virus that affects the central nervous system of newborns, a parasitic worm infection, a form of muscular dystrophy and a rare lung disease.

16 Nov 2011

N.Y. State Senator opens Einstein's new Cognitive Neurophysiology Lab

New York State Senator Jeffrey D. Klein joined administrators and faculty members of Albert Einstein College of Medicine of Yeshiva University last Friday to officially open their new Cognitive Neurophysiology Laboratory.

16 Nov 2011

Study confirms link between CMV and mucoepidermoid carcinoma

An important new study from the Laboratory for Developmental Genetics at USC has confirmed cytomegalovirus (CMV) as a cause of the most common salivary gland cancers. CMV joins a group of fewer than 10 identified oncoviruses - cancer-causing viruses - including HPV.

16 Nov 2011

Type 2 diabetics with low cholesterol may carry residual risk of cardiac events

LipoScience, Inc., an in-vitro diagnostic company advancing patient care in cardiovascular, metabolic and other diseases using an innovative and proprietary platform based on nuclear magnetic resonance (NMR) technology, recognizes a presentation of clinical data which suggests that type 2 diabetics with low non-HDL and low LDL cholesterol may carry residual risk of a cardiac event based on high LDL particle numbers.

16 Nov 2011

InVivo Therapeutics reports net income of $3,067,000 for third quarter 2011

InVivo Therapeutics Holdings Corp., a developer of groundbreaking technologies for the treatment of spinal cord injuries (SCI), today reported financial results for the three and nine months ended September 30, 2011 and provided a business update.

15 Nov 2011

Alcohol-based hand sanitizer helps reduce influenza A in children

A hand and respiratory hygiene program including frequent use of alcohol-based hand sanitizer helps reduce illness caused by influenza A and missed school days in elementary school children, reports a study in the November issue of The Pediatric Infectious Disease Journal. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

15 Nov 2011

NPR: VA is creating medical data 'gold mine'

"Not only do we have all their clinical records - laboratory, vital signs, pharmacy database - we have annual assessments that we will do that we can track people, assessments of depression, PTSD, suicide screening, alcohol and substances, traumatic brain injury," says Dr. Jennifer Hoblyn, who specializes in mental illness at the VA of Palo Alto. The VA will remove the names, so the data are anonymous.

15 Nov 2011

Researchers in Philippines develop machine to quickly detect drug-resistant TB

In this post in the Global Post's "Global Pulse" blog, journalist John Donnelly reports on how a machine developed by researchers at the TB Laboratory at the Lung Center of the Philippines "that can detect multi-drug resistant tuberculosis (MDR-TB) in record time may revolutionize TB treatment."

15 Nov 2011

Prox1 gene plays a critical role in formation and maintenance of lymphatic system

A century after the valves that link the lymphatic and blood systems were first described, St. Jude Children's Research Hospital scientists have detailed how those valves form and identified a gene that is critical to the process.

15 Nov 2011

Kessler Foundation researchers to improve rehabilitation after stroke

Kessler Foundation received a $250,000 stroke research grant from the Wallerstein Foundation for Geriatric Life Improvement. Anna Barrett, MD, director of Stroke Rehabilitation Research at Kessler Foundation, will apply the funds to finding better ways to treat hidden disabilities that often complicate recovery after stroke.

15 Nov 2011

Lentigen, UH Case Medical Center initiate LG631 Phase I trial in glioblastoma

University Hospitals (UH) Case Medical Center, Case Western Reserve University School of Medicine and Lentigen Corporation announced today the initiation of a novel Phase I clinical trial of LG631 gene therapy for the protection of hematopoietic stem cells (HSCs) from the dose limiting toxicity of chemotherapy with Temodar.

15 Nov 2011

Fetal stem cells play an important role in inducing maternal cardiac repair

Researchers from Mount Sinai School of Medicine have discovered the therapeutic benefit of fetal stem cells in helping the maternal heart recover after heart attack or other injury.

14 Nov 2011

Lower glycemic index diet may delay onset of AMD-like lesions

Feeding older mice a lower glycemic index (GI) diet consisting of slowly-digested carbohydrates delays the onset of age-related, sight-threatening retinal lesions, according to a new study from the Laboratory for Nutrition and Vision Research at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University.

14 Nov 2011

Cultured ES cells can self-organize into three-dimensional tissue-like structures

The possibility that functional, three-dimensional tissues and organs may be derived from pluripotent cells, such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), represents one of the grand challenges of stem cell research, but is also one of the fundamental goals of the emerging field of regenerative medicine.

14 Nov 2011

Decision Simulation licenses virtual patient platform from University of Pittsburgh

Decision Simulation LLC, the leading provider of web-based virtual patient platforms that enhance clinical decision-making skills, today announced it has extended its licensing agreement with the University of Pittsburgh.

14 Nov 2011

Great Basin seeks FDA 510(k) approval for C. difficile molecular diagnostic test

Great Basin Corporation, a privately held life sciences company developing sample-to-result molecular diagnostic solutions, today announced it has submitted a 510(k) application to the U.S. Food and Drug Administration (FDA) for its first molecular diagnostic test for Clostridium difficile (C. diff).

14 Nov 2011