Protein C News and Research

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Coating implants with tissue plasminogen activator can prevent biofilm-related infections

Biofilms--mats of bacteria similar to the plaque that grows on teeth--frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can threaten lives or lead to failure of the implants. Antibiotics are impotent against biofilms.

31 Oct 2015

Prkci gene maintains balance in stem cell production

When it comes to stem cells, too much of a good thing isn't wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance of the body.

31 Oct 2015

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

The Ebola virus acts fast. The course of infection, from exposure to recovery, or death, can take as little as two weeks. That may not leave enough time for the immune system to mount an effective response.

31 Oct 2015

RNA profiles of tumor-educated platelets may diagnose cancer, identify potential therapeutic approaches

Analysis of tumor RNA carried in platelets - blood components best known for their role in clotting - may prove to be more useful than other "liquid biopsy" technologies for diagnosing cancer and determining its primary location and potential therapeutic approaches.

31 Oct 2015

Researchers discover key regulator that impacts survival of lymphoma patients

An important regulator that controls the ability of tumour cells to hide from the immune system in lymphoma patients, making them unlikely to respond to standard treatment, has been discovered by scientists at the University of Oxford.

31 Oct 2015

Low-fat diets do not lead to greater weight loss in long term, shows meta-analysis research

Low-fat diets do not lead to greater weight loss in the long term compared to higher-fat diets of similar intensity, according to a large meta-analysis involving more than 68000 adults, published in The Lancet Diabetes & Endocrinology journal.

31 Oct 2015

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

Scientists at the University of Cambridge have identified a new property of essential proteins which, when it malfunctions, can cause the build up, or 'aggregation', of misshaped proteins and lead to serious diseases.

31 Oct 2015

Lack of adequate sleep can interfere with fundamental cellular process

Lack of adequate sleep can do more than just make you tired. It can short-circuit your system and interfere with a fundamental cellular process that drives physical growth, physiological adaptation and even brain activity, according to a new study from the University of Tennessee, Knoxville.

30 Oct 2015

Diet missing soluble fiber promotes inflammation in the intestines, leading to weight gain

Eating too much high-fat, high-calorie food is considered the primary cause of obesity and obesity-related disease, including diabetes. While the excess calories consumed are a direct cause of the fat accumulation, scientists suspect that low-grade inflammation due to an altered gut microbiome may also be involved.

30 Oct 2015

Specialized type of immunotherapy can boost survival from pancreatic cancer

A new study in mice by researchers at Fred Hutchinson Cancer Research Center has found that a specialized type of immunotherapy — even when used without chemotherapy or radiation — can boost survival from pancreatic cancer, a nearly almost-lethal disease, by more than 75 percent. The findings are so promising, human clinical trials are planned within the next year.

30 Oct 2015

Findings could lead to new treatment for ALS, dementia

University of Toronto (U of T) researchers are proposing a new way of understanding Amyotrophic Lateral Sclerosis (ALS), the devastating and incurable neurological disease. Their findings, published today in the journal Neuron, could be a major milestone on the path to a treatment for both ALS and dementia.

30 Oct 2015

Single gene variation may influence obesity in children, adults

A single variation in the gene for brain-derived neurotropic factor (BDNF) may influence obesity in children and adults, according to a new study funded by the National Institutes of Health.

30 Oct 2015

Study reveals mechanism behind protein-related diseases

Dartmouth researchers have found that some proteins turn into liquid droplets on the way to becoming toxic solids implicated in neurodegenerative diseases and other genetic disorders.

30 Oct 2015

Researchers identify molecular switch that can convert unhealthy white fat into energy-burning brown fat

A research team led by UC San Francisco scientists has identified a molecular switch capable of converting unhealthy white fat into healthy, energy-burning brown fat in mice. Drugs that flip this switch rapidly reduced obesity and diabetes risk factors in mice fed a high fat diet.

30 Oct 2015

Scientists one step closer to developing new treatment for inflammatory bowel disease

For patients with inflammatory bowel disease, the possibility of taking a single pill to bring long-lasting relief might seem too good to be true. Scientists at the Lewis Katz School of Medicine at Temple University are on the brink of making that happen, thanks to a recent proof-of-concept study, in which the severity of a form of inflammatory bowel disease in mice was dramatically reduced with one oral dose of a protein isolated from a bacterial biofilm.

30 Oct 2015

President and CEO of Protein Sciences elected as 2015 Fellow of the International Society for Vaccines

Protein Sciences Corporation, the makers of Flublok Influenza Vaccine, announced today that Dr. Manon Cox, President and CEO, was elected as a 2015 Fellow of the International Society for Vaccines (ISV). The ISV is an esteemed organization dedicated to the development, advancement and use of vaccines to prevent and control disease.

30 Oct 2015

Adelaide researchers identify key protein involved in 'super-inflammatory' immune response

Researchers have made another important step in the progress towards being able to block the development of multiple sclerosis (MS) and other autoimmune diseases.

29 Oct 2015

New research shows that autophagy can operate in cell nucleus to guard against start of cancer

Autophagy, literally self-eating or the degradation of unwanted cellular bits and pieces by the cell itself, has been shown for the first time to also work in the cell nucleus. In addition, in this setting it plays a role in guarding against the start of cancer, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

29 Oct 2015

Rutgers Cancer Institute scientist leads phase III trial of FDA-approved viral melanoma therapy

The U.S. Food and Drug Administration has approved a viral melanoma therapy that was the focus of a phase III clinical trial led by Rutgers Cancer Institute of New Jersey Associate Director for Clinical Science and Chief Surgical Officer Howard L. Kaufman, MD, FACS.

29 Oct 2015

Dementia specialists, PET imaging providers can now register to participate in IDEAS Study

Dementia specialists and PET imaging providers can now register to participate in the Imaging Dementia - Evidence for Amyloid Scanning (IDEAS) Study at Ideas-Study.org.

29 Oct 2015

Protein C News and Research

Coating implants with tissue plasminogen activator can prevent biofilm-related infections

Prkci gene maintains balance in stem cell production

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

RNA profiles of tumor-educated platelets may diagnose cancer, identify potential therapeutic approaches

Researchers discover key regulator that impacts survival of lymphoma patients

Low-fat diets do not lead to greater weight loss in long term, shows meta-analysis research

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

Lack of adequate sleep can interfere with fundamental cellular process

Diet missing soluble fiber promotes inflammation in the intestines, leading to weight gain

Specialized type of immunotherapy can boost survival from pancreatic cancer

Findings could lead to new treatment for ALS, dementia

Single gene variation may influence obesity in children, adults

Study reveals mechanism behind protein-related diseases

Researchers identify molecular switch that can convert unhealthy white fat into energy-burning brown fat

Scientists one step closer to developing new treatment for inflammatory bowel disease

President and CEO of Protein Sciences elected as 2015 Fellow of the International Society for Vaccines

Adelaide researchers identify key protein involved in 'super-inflammatory' immune response

New research shows that autophagy can operate in cell nucleus to guard against start of cancer

Rutgers Cancer Institute scientist leads phase III trial of FDA-approved viral melanoma therapy

Dementia specialists, PET imaging providers can now register to participate in IDEAS Study

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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