Protein C News and Research

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GDF10 molecule identified as a key player in repair mechanisms after stroke

Looking at brain tissue from mice, monkeys and humans, scientists have found that a molecule known as growth and differentiation factor 10 (GDF10) is a key player in repair mechanisms following stroke. The findings suggest that GDF10 may be a potential therapy for recovery after stroke.

29 Oct 2015

Upstream Medical Technologies formed to revolutionise accurate diagnosis of heart conditions

A new company that could revolutionise the accurate diagnosis of heart conditions was launched in Christchurch, New Zealand today.

29 Oct 2015

Researchers report new way to help improve vaccines using molecules that direct the immune system

As the days get colder and shorter, we carve jack-o-lanterns and drink pumpkin spice lattes. But one fall tradition can actually keep you healthy: getting your flu shot. Like all vaccines, the flu shot trains the immune system to fend off infection, but some need help to produce the full effect.

29 Oct 2015

New broad-spectrum antibiotic can kill bacteria by punching holes in their membranes

Bacteria have many methods of adapting to resist antibiotics, but a new class of spiral polypeptides developed at the University of Illinois targets one thing no bacterium can live without: an outer membrane.

29 Oct 2015

Liposomal sizing and the Coulter principle: an interview with Professor Melvin E. Klegerman

For about the last 25 years, the cardiology group here have been developing a platform technology for both the diagnosis and treatment of atherosclerosis.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 28 Oct 2015

Researchers identify inherited gene variation associated with pediatric acute lymphoblastic leukemia

Researchers studying two generations of a family affected by pediatric acute lymphoblastic leukemia (ALL) have identified an inherited variation in the ETV6 gene that is associated with an increased risk of developing the disease. St. Jude Children's Research Hospital investigators led the study, which appears in the October 28 issue of the journal Lancet Oncology.

28 Oct 2015

Expectant mothers encouraged to eat balanced diet to reduce obesity risk in unborn child

Overweight and obese women who gain excessive weight during pregnancy may be putting their babies at risk of a lifetime of obesity.

28 Oct 2015

Researchers identify role of cGAS enzyme in autoimmune diseases

Activating an enzyme that sounds an alarm for the body's innate immune system causes two lethal autoimmune diseases in mice, while inhibiting the same enzyme rescues them, UT Southwestern Medical Center researchers report.

28 Oct 2015

Study suggests potential new way to block cancer-causing gene

A new study suggests a potential new way to block one of the most common cancer-causing genes, without causing severe side effects.

28 Oct 2015

Research provides novel insight into potential new therapeutic targets for triple-negative breast cancer

Recent laboratory findings provide novel insight into potential new therapeutic approaches for triple-negative breast cancer, a particularly difficult to treat and aggressive form of the disease.

28 Oct 2015

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

An intestinal patch device containing insulin that can be swallowed in the form of a capsule, in development by researchers at University of California Santa Barbara, has demonstrated efficacy of blood glucose management in diabetic rats. This work is being presented Oct. 27 at the 2015 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in Orlando, Fla. Oct. 25-29.

28 Oct 2015

Motor proteins can stimulate growth of microtubules

Motor proteins that pause at the ends of microtubules and produce pushing forces can also stimulate their growth, according to researchers at Penn State. The proteins' function could be a critical component in understanding cell division and nerve branching and growth.

27 Oct 2015

Changes in lifestyle could reduce Alzheimer's disease risk

Changes in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University's Network Aging Research, who examined the data from two independent epidemiological studies. Carriers of the ApoE4 genetic risk factor for Alzheimer's may be able to reduce their increased risk of cognitive decline by reducing their cholesterol level, especially if they also suffer from cardiovascular disease.

27 Oct 2015

Reducing sugar intake reverses chronic metabolic diseases in children

Reducing consumption of added sugar, even without reducing calories or losing weight, has the power to reverse a cluster of chronic metabolic diseases, including high cholesterol and blood pressure, in children in as little as 10 days, according to a study by researchers at UC San Francisco and Touro University California.

27 Oct 2015

Love hormone may enhance pleasure of social interactions, UCI study finds

The hormone oxytocin, which has been associated with interpersonal bonding, may enhance the pleasure of social interactions by stimulating production of marijuana-like neurotransmitters in the brain, according to a University of California, Irvine study.

27 Oct 2015

Discovery may open new doors to understanding how melanoma grows and spreads

Of the hundreds of genes that can be mutated in a single case of melanoma, only a handful may be true "drivers" of cancer. In research that recently appeared in Nature Genetics, a Weizmann Institute of Science team has now revealed one of the drivers of a particularly deadly subset of melanomas that is seeing a rise in new cases.

27 Oct 2015

U-M study suggests new therapeutic strategy for treating Duchene muscular dystrophy

Every heart beat and step in our daily lives is dependent on the integrity of muscles and the proteins that keep them strong and free of injury as they contract and relax.

27 Oct 2015

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Four tiny segments of RNA appear to play critical roles in controlling cholesterol and triglyceride metabolism. In their report receiving advance online publication in Nature Medicine, a Massachusetts General Hospital-based research team describes finding how these microRNAs could reduce the expression of proteins playing key roles in the generation of beneficial HDL cholesterol, the disposal of artery-clogging LDL cholesterol, control of triglyceride levels and other risk factors of cardiovascular disease.

27 Oct 2015

Researchers develop multiplexed screening approach to study cancer development in mice

In a novel use of the CRISPR/Cas9 system, which can be deployed to switch genes off, researchers from Germany, the UK and Spain have developed a multiplexed screening approach to study and model cancer development in mice. The scientists mutated genes in the adult mouse liver uncovering their cancer-causing roles and determining which combinations of genes cooperate to cause liver cancer.

27 Oct 2015

Unique, tiny protein cage developed to deliver chemotherapy chemicals directly to cancer cells

Washington State University researchers have developed a unique, tiny protein cage to deliver nasty chemotherapy chemicals directly to cancer cells. Direct delivery could improve treatment and lessen what can be horrendous side effects from toxic drugs.

27 Oct 2015

Protein C News and Research

GDF10 molecule identified as a key player in repair mechanisms after stroke

Upstream Medical Technologies formed to revolutionise accurate diagnosis of heart conditions

Researchers report new way to help improve vaccines using molecules that direct the immune system

New broad-spectrum antibiotic can kill bacteria by punching holes in their membranes

Liposomal sizing and the Coulter principle: an interview with Professor Melvin E. Klegerman

Researchers identify inherited gene variation associated with pediatric acute lymphoblastic leukemia

Expectant mothers encouraged to eat balanced diet to reduce obesity risk in unborn child

Researchers identify role of cGAS enzyme in autoimmune diseases

Study suggests potential new way to block cancer-causing gene

Research provides novel insight into potential new therapeutic targets for triple-negative breast cancer

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

Motor proteins can stimulate growth of microtubules

Changes in lifestyle could reduce Alzheimer's disease risk

Reducing sugar intake reverses chronic metabolic diseases in children

Love hormone may enhance pleasure of social interactions, UCI study finds

Discovery may open new doors to understanding how melanoma grows and spreads

U-M study suggests new therapeutic strategy for treating Duchene muscular dystrophy

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Researchers develop multiplexed screening approach to study cancer development in mice

Unique, tiny protein cage developed to deliver chemotherapy chemicals directly to cancer cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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