Protein C News and Research

RSS

Sigma-Aldrich, Sanger Institute partner to manufacture and distribute arrayed lentiviral CRISPR library

Sigma-Aldrich Corporation today announced it has entered into an exclusive agreement with the Wellcome Trust Sanger Institute to manufacture and distribute the Sanger Institute's arrayed lentiviral CRISPR library. The library will be the first of its kind, providing researchers with a collection of individual clones designed to knock out every known human and mouse protein-coding gene using the CRISPR system.

20 Oct 2015

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Ember Therapeutics, Inc., a privately held, New York-based biopharmaceutical company that is developing targeted therapies for osteoarthritis, kidney fibrosis, and other indications using Bone Morphogenetic Protein (BMP)-7, announced today initial results from the Phase II(a) trial of local BMP-7 administration in patients with moderate osteoarthritis of the knee.

20 Oct 2015

Diabetic retinopathy therapy innovations: an interview with Richard Kirk, CEO of Polyphotonix

In the UK there are currently over 3.5 million people who have diabetes, with a growth rate exceeding 280,000 people per year. Diabetic retinopathy is the most common complication of diabetes.

19 Oct 2015

Breakthrough advancements on new molecular mechanism may lead to Parkinson's treatments

More than one million people in the United States are afflicted with Parkinson's disease, a progressive disorder of the brain that affects movement and coordination. The cause is typically unknown, and presently there is no cure for the disease.

19 Oct 2015

UB study sheds light on the root causes of Huntington's disease

We've known for years that the Huntingtin protein (Htt) is responsible for Huntington's disease, a neurodegenerative disorder that diminishes a person's mental and physical abilities.

19 Oct 2015

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center where most of its DNA is stored.

19 Oct 2015

TGen researchers join international scientists in discovering how malaria protein could some day help stop cancer

Researchers at the Translational Genomics Research Institute joined an international team of scientists in discovering how a protein from malaria could some day help stop cancer.

19 Oct 2015

OSU discovery sheds new light on how proteins fold

Biochemists at Oregon State University have made a fundamental discovery about protein structure that sheds new light on how proteins fold, which is one of the most basic processes of life.

19 Oct 2015

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

Neural stem cells transplanted into damaged brain sites in mice dramatically improved both motor and cognitive impairments associated with dementia with Lewy bodies, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

19 Oct 2015

BET protein family plays key role in regulation of normal neuronal development and function

Regulation of a family of brain proteins known as bromodomain and extra-terminal domain containing transcription regulators (BETs) plays a key role in normal cognition and behavior, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published advanced online on September 21 and in print October 19 in The Journal of Experimental Medicine.

19 Oct 2015

CNIO researchers identify molecular mechanisms that determine cancer predisposition in DBA patients

Researchers from the Tumour Suppression Group at the Spanish National Cancer Research Centre, headed by Manuel Serrano, have discovered the molecular mechanisms that determine cancer predisposition in patients with Diamond-Blackfan anaemia (DBA).

18 Oct 2015

New zebrafish study provides insights into causes of congenital heart defects

Researchers working with zebrafish at New Zealand's University of Otago have published a study providing new insights into the causes of the congenital heart defects associated with a rare developmental disorder.

16 Oct 2015

New research raises hope for novel cancer immunotherapy

New research by Dana-Farber Cancer Institute scientists raises the prospect of cancer therapy that works by converting a tumor's best friends in the immune system into its gravest enemies.

16 Oct 2015

Hiroshima University researchers demonstrate how Sendai virus escapes host immune system

A research group at Hiroshima University demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal transduction pathway of interferon gamma.

16 Oct 2015

Protein C News and Research

Sigma-Aldrich, Sanger Institute partner to manufacture and distribute arrayed lentiviral CRISPR library

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Diabetic retinopathy therapy innovations: an interview with Richard Kirk, CEO of Polyphotonix

Breakthrough advancements on new molecular mechanism may lead to Parkinson's treatments

UB study sheds light on the root causes of Huntington's disease

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

TGen researchers join international scientists in discovering how malaria protein could some day help stop cancer

OSU discovery sheds new light on how proteins fold

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

BET protein family plays key role in regulation of normal neuronal development and function

CNIO researchers identify molecular mechanisms that determine cancer predisposition in DBA patients

New zebrafish study provides insights into causes of congenital heart defects

New research raises hope for novel cancer immunotherapy

Hiroshima University researchers demonstrate how Sendai virus escapes host immune system

Analysis of high-throughput sequencing data reveals new genes linked to chronic lymphocytic leukemia

New breakthrough advances our understanding of how brain detects, prevents dehydration

Researchers create high resolution images of telomerase that plays major role in cancer, aging

Study identifies proteins that could help in treating deafness

New COMPASS platform points directly to protein's likely structure

Study shows why cancer anemia therapy stimulates tumor growth

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News