Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

NUS researchers identify molecular switch that makes breast cancer cells more aggressive

A team of scientists from the National University of Singapore (NUS) has established novel insights into the relationship between breast cancer tumour intracellular redox environment and the cancer cells' ability to become invasive.

1 Nov 2016

Researchers identify protein linked to negative effects of senescence

Cellular senescence is a state in which normal healthy cells do not have the ability to divide. Senescence can occur when cancer-causing genes are activated in normal cells or when chemotherapy is used on cancer cells.

1 Nov 2016

Study identifies potential pathway to improve rate at which the body burns calories

Researchers say they have identified a potential pathway in our muscle tissue to improve the rate at which our bodies burn calories.

1 Nov 2016

New study to explore impact of vitamin K supplement on cardiovascular health of obese children

Researchers want to know whether a vitamin K supplement is an effective, inexpensive way to help reduce the cardiovascular risk of obese children.

1 Nov 2016

Two genes linked to increase in immunity to hepatitis C after childbirth, study shows

Alternative forms of two genes are associated with a boost in immunity to hepatitis C after childbirth, a study led by a Nationwide Children's Hospital physician-researcher shows.

31 Oct 2016

Researchers identify two new potential drug targets for treating atherosclerosis

Researchers at Brigham and Women's Hospital have found two new potential drug targets for treating arterial diseases such as atherosclerosis.

31 Oct 2016

Nano-biointeraction and nanopathology

Nanoparticles enter the organism in a number of ways. In most cases through inhalation and ingestion. When inhaled, the majority of them are expelled with the next breath. When ingested, most of them are gotten rid of through feces.

31 Oct 2016

Distinct structures of tau protein aggregates may help determine type of dementia, study shows

The distinct structures of toxic protein aggregates that form in degenerating brains determine which type of dementia will occur, which regions of brain will be affected, and how quickly the disease will spread, according to a study from the Peter O'Donnell Jr. Brain Institute.

31 Oct 2016

Turning off TAZ protein in liver cells reverses fibrosis in mice

Scientists at Columbia University Medical Center have identified a factor in liver cells that is responsible for turning a relatively benign liver condition, present in 30 percent of U.S. adults, into a serious disease that can lead to liver failure.

27 Oct 2016

Researchers develop new blood test for diagnosis of early-stage osteoarthritis

Patients could soon be diagnosed with early-stage arthritis several years before the onset of physical and irreversible symptoms, thanks to a new test developed by researchers at the University of Warwick.

27 Oct 2016

NIH researchers identify novel role for Hsp60 protein in tissue regeneration and wound healing

National Institutes of Health researchers have identified a novel role for a gene known as heat shock protein 60 (Hsp60), finding that it is critical in tissue regeneration and wound healing.

27 Oct 2016

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Even though it's almost impossible to see, computational biophysicist Rommie Amaro is using the Stampede supercomputer at the Texas Advanced Computing Center at The University of Texas at Austin to model the largest atomic level system of the tumor suppression protein p53 to date -- over 1.5 million atoms.

27 Oct 2016

Breakthrough research paves way for developing new asthma treatments

'The study demonstrated for the first time that a protein called PP5 was significantly upregulated in the lungs of severe asthmatic patients compared to healthy controls. We are extremely excited by this paradigm shift observation.' - Dr Yassine Amrani, University of Leicester.

27 Oct 2016

Research could pave way for new approaches to kill antibiotic-resistant E. coli bacteria

Research by bioscientists at the University of Kent and the University of Queensland is expected to pave the way for new approaches to kill bacteria that no longer respond to conventional antibiotics.

27 Oct 2016

How to improve your chromatin immunoprecipitation experiments

Chromatrap® has published a comprehensive Applications Compendium that includes hints and tips to improve your Chromatin Immunoprecipitation (ChIP) experiments, increase the effectiveness of your ChIP-seq library preparation and brings together its latest application notes in one informative document.

From Chromatrap® - Porvair Sciences Ltd 27 Oct 2016

Mitochondria regulates stem cell proliferation in gut epithelium, study shows

What happens in intestinal epithelial cells during a chronic illness? Basic research conducted at the Chair of Nutrition and Immunology at the Technical University of Munich addressed this question by generating a new model system.

27 Oct 2016

TSRI scientists discover key molecular player in inherited disorder and morphine addiction

In a remarkable "two for one" discovery, scientists from the Florida campus of The Scripps Research Institute have illuminated a key molecular player in the addictive effects of morphine in animal models.

27 Oct 2016

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

The study began by taking the medical history of 11 children, all of whom had a disorder due to mycobacteria infections, as the basis. All were discovered to have the same phenotype with the same mutation, which was located in the interferon-gamma (IFNGR) receptor, so the group began to explore what was causing this dysfunction.

27 Oct 2016

Study reveals way to actively reverse anesthetic-induced unconsciousness

The latest study from a Massachusetts General Hospital/Massachusetts Institute of Technology team investigating the mechanisms underlying general anesthesia finds that stimulating a specific group of neurons in mice produces signs of arousal -- including getting on their feet and walking -- even as the animals continue to receive the anesthetic drug isoflurane.

27 Oct 2016

New technique shows promise for therapeutic reversal of food allergies

"This discovery reverses food allergies in mice, and we have many people with allergies volunteering their own cells for us to use in lab testing to move this research forward," said professor John Gordon, lead scientist behind the discovery just published in the current issue of the Journal of Allergy and Clinical Immunology.

27 Oct 2016

Protein News and Research

Further Reading

NUS researchers identify molecular switch that makes breast cancer cells more aggressive

Researchers identify protein linked to negative effects of senescence

Study identifies potential pathway to improve rate at which the body burns calories

New study to explore impact of vitamin K supplement on cardiovascular health of obese children

Two genes linked to increase in immunity to hepatitis C after childbirth, study shows

Researchers identify two new potential drug targets for treating atherosclerosis

Nano-biointeraction and nanopathology

Distinct structures of tau protein aggregates may help determine type of dementia, study shows

Turning off TAZ protein in liver cells reverses fibrosis in mice

Researchers develop new blood test for diagnosis of early-stage osteoarthritis

NIH researchers identify novel role for Hsp60 protein in tissue regeneration and wound healing

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Breakthrough research paves way for developing new asthma treatments

Research could pave way for new approaches to kill antibiotic-resistant E. coli bacteria

How to improve your chromatin immunoprecipitation experiments

Mitochondria regulates stem cell proliferation in gut epithelium, study shows

TSRI scientists discover key molecular player in inherited disorder and morphine addiction

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

Study reveals way to actively reverse anesthetic-induced unconsciousness

New technique shows promise for therapeutic reversal of food allergies

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