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Common medications reduce brain plaques in mice

Multiple drug classes commonly prescribed for common medical conditions are capable of influencing the onset and progression of Alzheimer's disease, according to researchers at The Mount Sinai Medical Center. The findings are published online in the journal PLoS One.

13 Jun 2013

Understanding Phelan-McDermid Syndrome

In the first prospective study of its kind, Seaver Autism Center researchers at the Icahn School of Medicine at Mount Sinai provide new evidence of the severity of intellectual, motor, and speech impairments in a subtype of autism called Phelan-McDermid Syndrome.

12 Jun 2013

2013 World Stem Cell Report to be published as special supplement to journal Stem Cells and Development

The Genetics Policy Institute and Mary Ann Liebert, Inc., publishers have announced that the 2013 World Stem Cell Report will be published as a special supplement to the peer-reviewed journal Stem Cells and Development. Dr. Graham Parker and Bernard Siegel will serve as Co-Editors-in-Chief, joined by Rosario Isasi (McGill University) as Managing Editor.

11 Jun 2013

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

By applying light stimulation to highly specific neurons in the brain, the researchers managed to re-establish normal behaviour in mice that had beforehand presented pathological repetitive behaviour similar to that observed in human patients suffering from obsessive-compulsive disorders.

10 Jun 2013

Discovery of impaired molecular pathway may help treat children with leukemia

Through genetic engineering of laboratory models, researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center have uncovered a vulnerability in the way cancer cells diverge from normal regenerating cells that may help treat children with leukemia as reported in the journal PNAS on June 3, 2013.

7 Jun 2013

HSV-1 exploits immune system receptor to boost infectivity and cause disease

Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an immune system receptor to boost its infectivity and ability to cause disease.

7 Jun 2013

Better understanding of breast milk variability, strategies for optimizing neonatal diet

The composition of breast milk varies from mother to mother, and genetic factors may affect the levels of protective components in breast milk that could influence a newborn's outcomes.

5 Jun 2013

Blocking MHCII action rescues nerve cells from Parkinson's disease mechanisms, researchers find

The same mechanism that lets the immune system mount a massive attack against invading bacteria contributes to the destruction of brain cells as part of Parkinson's disease, according to a study published online today in the Journal of Neuroscience.

5 Jun 2013

Discovery could reveal potential new drug options for malaria treatment

Malaria parasites that develop resistance to the most effective class of anti-malarial drugs may become susceptible to other treatments as a result. The discovery could reveal potential new drug options, which would be essential in the event of resistance to the best anti-malarials.

4 Jun 2013

Genetically engineered immune cells appear to promote healing in mice infected with MS-like disease

Genetically engineered immune cells seem to promote healing in mice infected with a neurological disease similar to multiple sclerosis (MS), cleaning up lesions and allowing the mice to regain use of their legs and tails.

1 Jun 2013

Research gives hope: Patients' immune system could fight glioblastoma multiforme

Research at Lund University in Sweden gives hope that one of the most serious types of brain tumour, glioblastoma multiforme, could be fought by the patients' own immune system.

31 May 2013

Gene therapy techniques show promise in promoting growth of skin, bone and other tissues

Experimental genetic techniques may one day provide plastic and reconstructive surgeons with an invaluable tool-the ability to promote growth of the patient's own tissues for reconstructive surgery.

30 May 2013

Researchers tie traumatic brain injury to toxic form of protein

University of Texas Medical Branch at Galveston researchers have uncovered what may be a key molecular mechanism behind the lasting damage done by traumatic brain injury.

30 May 2013

$2 million grant to provide instrumentation, core facilities devoted to synthetic biology

The Roy J. Carver Charitable Trust has awarded a $2 million grant to the Institute for Genomic Biology at the University of Illinois at Urbana-Champaign. Under the leadership of Principal Investigator Dr. Huimin Zhao and co-Principal Investigator Dr. Christopher Rao, the grant will be disbursed over two years to provide instrumentation and core facilities for a new research theme devoted to the new scientific subdiscipline of synthetic biology.

29 May 2013

Transplantation of human stem cells improves muscle function in rats used to model ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

29 May 2013

Neuroscientists identify key circuit elements that contribute to everyday decision in ACC

You are sitting on your couch flipping through TV channels trying to decide whether to stay put or get up for a snack. Such everyday decisions about whether to "stay" or to "go" are supported by a brain region called the anterior cingulate cortex (ACC), which is part of the prefrontal cortex.

27 May 2013

Research findings may offer new hope to stroke victims

A study by researchers at Henry Ford Hospital found "substantial evidence" that a regenerative process involving damaged nerve fibers in the spinal cord could hold the key to better functional recovery by most stroke victims.

24 May 2013

Novel multiplex immunoassay approach to capture HIV antibodies

Detection of HIV antibodies is used to diagnose HIV infection and monitor trials of experimental HIV/AIDS vaccines. New, more sensitive detection systems being developed use microspheres to capture HIV antibodies and can measure even small amounts of multiple antibodies at one time.

24 May 2013

New approach to genetic engineering reduces time and effort needed to insert genes into bacteria

A new, streamlined approach to genetic engineering drastically reduces the time and effort needed to insert new genes into bacteria, the workhorses of biotechnology, scientists are reporting.

24 May 2013

Scientists bioengineer novel molecule to kill tumour cells

Scientists from Nanyang Technological University and Lund University, Sweden, have bioengineered a novel molecule which has been proven to successfully kill tumour cells.

21 May 2013

Genetic Engineering News and Research

Common medications reduce brain plaques in mice

Understanding Phelan-McDermid Syndrome

2013 World Stem Cell Report to be published as special supplement to journal Stem Cells and Development

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

Discovery of impaired molecular pathway may help treat children with leukemia

HSV-1 exploits immune system receptor to boost infectivity and cause disease

Better understanding of breast milk variability, strategies for optimizing neonatal diet

Blocking MHCII action rescues nerve cells from Parkinson's disease mechanisms, researchers find

Discovery could reveal potential new drug options for malaria treatment

Genetically engineered immune cells appear to promote healing in mice infected with MS-like disease

Research gives hope: Patients' immune system could fight glioblastoma multiforme

Gene therapy techniques show promise in promoting growth of skin, bone and other tissues

Researchers tie traumatic brain injury to toxic form of protein

$2 million grant to provide instrumentation, core facilities devoted to synthetic biology

Transplantation of human stem cells improves muscle function in rats used to model ALS

Neuroscientists identify key circuit elements that contribute to everyday decision in ACC

Research findings may offer new hope to stroke victims

Novel multiplex immunoassay approach to capture HIV antibodies

New approach to genetic engineering reduces time and effort needed to insert genes into bacteria

Scientists bioengineer novel molecule to kill tumour cells

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